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Träfflista för sökning "WFRF:(Pfeiffer R. F.) "

Search: WFRF:(Pfeiffer R. F.)

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1.
  • Aad, G, et al. (author)
  • 2015
  • swepub:Mat__t
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2.
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:2
  • Journal article (peer-reviewed)
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3.
  • Mishra, A, et al. (author)
  • Diminishing benefits of urban living for children and adolescents' growth and development
  • 2023
  • In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 615:7954, s. 874-883
  • Journal article (peer-reviewed)abstract
    • Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified.
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6.
  • Delios, A., et al. (author)
  • Examining the generalizability of research findings from archival data
  • 2022
  • In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 119:30
  • Journal article (peer-reviewed)abstract
    • This initiative examined systematically the extent to which a large set of archival research findings generalizes across contexts. We repeated the key analyses for 29 original strategic management effects in the same context (direct reproduction) as well as in 52 novel time periods and geographies; 45% of the reproductions returned results matching the original reports together with 55% of tests in different spans of years and 40% of tests in novel geographies. Some original findings were associated with multiple new tests. Reproducibility was the best predictor of generalizability-for the findings that proved directly reproducible, 84% emerged in other available time periods and 57% emerged in other geographies. Overall, only limited empirical evidence emerged for context sensitivity. In a forecasting survey, independent scientists were able to anticipate which effects would find support in tests in new samples. 
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7.
  • Tierney, W., et al. (author)
  • A creative destruction approach to replication : Implicit work and sex morality across cultures
  • 2021
  • In: Journal of Experimental Social Psychology. - : Elsevier BV. - 0022-1031 .- 1096-0465. ; 93
  • Journal article (peer-reviewed)abstract
    • How can we maximize what is learned from a replication study? In the creative destruction approach to replication, the original hypothesis is compared not only to the null hypothesis, but also to predictions derived from multiple alternative theoretical accounts of the phenomenon. To this end, new populations and measures are included in the design in addition to the original ones, to help determine which theory best accounts for the results across multiple key outcomes and contexts. The present pre-registered empirical project compared the Implicit Puritanism account of intuitive work and sex morality to theories positing regional, religious, and social class differences; explicit rather than implicit cultural differences in values; self-expression vs. survival values as a key cultural fault line; the general moralization of work; and false positive effects. Contradicting Implicit Puritanism's core theoretical claim of a distinct American work morality, a number of targeted findings replicated across multiple comparison cultures, whereas several failed to replicate in all samples and were identified as likely false positives. No support emerged for theories predicting regional variability and specific individual-differences moderators (religious affiliation, religiosity, and education level). Overall, the results provide evidence that work is intuitively moralized across cultures.
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8.
  • Åsman, Barbro, et al. (author)
  • The ATLAS Level-1 Calorimeter Trigger : PreProcessor implementation and performance
  • 2012
  • In: Journal of Instrumentation. - 1748-0221. ; 7
  • Journal article (peer-reviewed)abstract
    • The PreProcessor system of the ATLAS Level-1 Calorimeter Trigger (L1Calo) receives about 7200 analogue signals from the electromagnetic and hadronic components of the calorimetric detector system. Lateral division results in cells which are pre-summed to so-called Trigger Towers of size 0.1 x 0.1 along azimuth (phi) and pseudorapidity (eta). The received calorimeter signals represent deposits of transverse energy. The system consists of 124 individual PreProcessor modules that digitise the input signals for each LHC collision, and provide energy and timing information to the digital processors of the L1Calo system, which identify physics objects forming much of the basis for the full ATLAS first level trigger decision. This paper describes the architecture of the PreProcessor, its hardware realisation, functionality, and performance.
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9.
  • Santangelo, James S., et al. (author)
  • Global urban environmental change drives adaptation in white clover
  • 2022
  • In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 375
  • Journal article (peer-reviewed)abstract
    • Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural dines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale.
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10.
  • Palmer, Nicholette D, et al. (author)
  • A genome-wide association search for type 2 diabetes genes in African Americans.
  • 2012
  • In: PloS one. - San Francisco : Public Library of Science (PLoS). - 1932-6203. ; 7:1, s. e29202-
  • Journal article (peer-reviewed)abstract
    • African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of this study was to identify genes associated with T2DM in the African American population. We performed a Genome Wide Association Study (GWAS) using the Affymetrix 6.0 array in 965 African-American cases with T2DM and end-stage renal disease (T2DM-ESRD) and 1029 population-based controls. The most significant SNPs (n = 550 independent loci) were genotyped in a replication cohort and 122 SNPs (n = 98 independent loci) were further tested through genotyping three additional validation cohorts followed by meta-analysis in all five cohorts totaling 3,132 cases and 3,317 controls. Twelve SNPs had evidence of association in the GWAS (P<0.0071), were directionally consistent in the Replication cohort and were associated with T2DM in subjects without nephropathy (P<0.05). Meta-analysis in all cases and controls revealed a single SNP reaching genome-wide significance (P<2.5×10(-8)). SNP rs7560163 (P = 7.0×10(-9), OR (95% CI) = 0.75 (0.67-0.84)) is located intergenically between RND3 and RBM43. Four additional loci (rs7542900, rs4659485, rs2722769 and rs7107217) were associated with T2DM (P<0.05) and reached more nominal levels of significance (P<2.5×10(-5)) in the overall analysis and may represent novel loci that contribute to T2DM. We have identified novel T2DM-susceptibility variants in the African-American population. Notably, T2DM risk was associated with the major allele and implies an interesting genetic architecture in this population. These results suggest that multiple loci underlie T2DM susceptibility in the African-American population and that these loci are distinct from those identified in other ethnic populations.
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  • Result 1-10 of 52
Type of publication
journal article (47)
research review (2)
reports (1)
conference paper (1)
Type of content
peer-reviewed (46)
other academic/artistic (5)
Author/Editor
Pfeiffer, P (6)
Pfeiffer, F (5)
van Laarhoven, HWM (5)
Liu, B. (4)
Hanna, GB (4)
Smyth, E (4)
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Lind, Lars (4)
Nilsson, M (4)
Roviello, F. (4)
Griffiths, EA (4)
Piessen, G (4)
Liakakos, T (4)
D'Ugo, D (4)
Thomas, M (4)
Markar, S (4)
Schneiderman, Justin ... (4)
van Hillegersberg, R (4)
Lordick, F. (4)
Alsina, M. (4)
Haustermans, K. (4)
Obermannová, R. (4)
Pfeiffer, Christoph, ... (4)
Pera, M (4)
Van Cutsem, E (4)
Rosati, R (4)
Bruns, CJ (4)
Nafteux, P (4)
Gockel, I (4)
Pfeiffer, Andreas F ... (4)
Cervantes, A. (4)
Pfeiffer, T. (4)
Nordsmark, M. (4)
Verheij, M. (4)
van Sandick, JW (4)
Slingerland, M. (4)
Kolodziejczyk, P (4)
Guckenberger, M (4)
Wijnhoven, B (4)
de Manzoni, G (4)
Pfeiffer, M. (4)
Castoro, C (4)
Moehler, M (4)
Kroese, TE (4)
Deseyne, PRAJ (4)
Elme, A (4)
Adenis, A (4)
Gani, C (4)
Bencivenga, M (4)
Jeene, P (4)
Berbee, M (4)
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University
Karolinska Institutet (23)
Lund University (16)
Uppsala University (11)
University of Gothenburg (9)
Chalmers University of Technology (6)
Umeå University (5)
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Stockholm University (5)
Royal Institute of Technology (4)
Stockholm School of Economics (3)
Mid Sweden University (1)
University of Skövde (1)
Swedish University of Agricultural Sciences (1)
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Language
English (52)
Research subject (UKÄ/SCB)
Medical and Health Sciences (20)
Natural sciences (15)
Engineering and Technology (6)
Social Sciences (3)
Humanities (1)

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