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- Adeback, Petra, et al.
(author)
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Children exposed to a natural disaster: psychological consequences eight years after 2004 tsunami
- 2018
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In: Nordic Journal of Psychiatry. - : TAYLOR & FRANCIS LTD. - 0803-9488 .- 1502-4725. ; 72:1, s. 75-81
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Research review (peer-reviewed)abstract
- Background: There is a need for studies that follow up children and adolescents for many years post disaster since earlier studies have shown that exposure during natural disasters constitutes a risk factor for poor psychological health.Aims: The main aim was to examine whether there was an association between severity of exposures during a natural disaster experienced in childhood or adolescence and posttraumatic stress symptoms, psychological distress, self-rated health, diagnosis of depression, anxiety or worry, thoughts about or attempted suicide, physical symptoms or daily functioning eight years later in young adulthood. A second aim was to compare psychological distress and self-rated health of exposed young adults with a matched population-based sample.Method: Young adults, who experienced the 2004 tsunami as children between 10 and 15 years of age, responded to a questionnaire eight years post disaster. The results were compared to a matched population sample.Results: The results showed that the likelihood for negative psychological outcomes was higher for those who had been exposed to several types of exposures during this natural disaster.Conclusions: The negative psychological impact on children and adolescents can still be present eight years post-disaster and seems to have association with the type of exposure; loss, physical presence and subjective experience. It is important for clinicians, who meet young adults seeking help, to be conscious about the impact as long as eight years post disaster and to be aware of possible clinical implications associated with severity of exposures.
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- Grander, Martin, 1978-
(author)
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Segmentering i bostadsbeståndet 2013-2017 : Utveckling av bostadsbestånd, demografi och socioekonomiska indikatorer i riket och storstäderna, med fördjupningar i Malmö och Göteborg
- 2020
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Reports (other academic/artistic)abstract
- Denna rapport, utarbetad inom ramen för forskningsprogrammet Nyttan med allmännyttan i praktiken samt forskningsprojektet Allmännyttan och blandningspolitikens praktik (Formas 2018-00063) vid Malmö universitets forskningsmiljö Studier i boende och välfärd (http://www.mau.se/sbv), presenterar en beskrivning och analys av befolkningsutvecklingen och förändringar i bostadsbeståndet mellan åren 2013–2017. Närmare bestämt studeras utvecklingen av bostadsbeståndet samt den demografiska förändringen och utvecklingen av befolkningens socioekonomiska förutsättningar per upplåtelseform i Sverige samt i storstadskommunerna Stockholm, Göteborgoch Malmö. Särskilda fördjupningar görs i Göteborg och Malmö. Syftet med texten är att utifrån de statistiska underlagen belysa och diskutera de olika upplåtelseformernas roll och funktion på lokala bostadsmarknader i demografisk förändring, med särskilt fokus på den allmännyttiga bostadssektorn.Rapporten pekar på en kraftig inkomstsegmentering mellan upplåtelseformerna, det vill säga att olika upplåtelseformer får alltmer ensartad sammansättning av hushåll när det gäller disponibel inkomst. Hyresrätten – och specifikt allmännyttan – blir i allt högre utsträckning en boendeform för hushåll med låga inkomster, medan inkomsterna i bostadsrätt och egnahem ökar betydligt mer än den generella utvecklingen. Denna utveckling i allmännyttan har pågått under en längre tid, men accentueras under perioden 2013–2017, där allmännyttan får en allt större andel hushåll inkomstfattiga. Nästan vartannat hushåll i allmännyttan har låg köpkraft. Samtidigt ser vi att andelen hushåll med hög köpkraft koncentreras i bostadsrätt. Vidare ökar segmenteringen mellan allmännyttig och privat hyresrätt kontinuerligt, vilket i praktiken innebär att den så kallade integrerade hyresmarknaden, där privata och allmännyttiga hyresvärdar konkurrerar om samma hyresgäster, alltmer framstår som en idealbild.
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- Timmusk, Sirje
(author)
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Studies of immunoglobulin light chains in rainbow trout (Oncorhynchus mykiss): new insight into the evolution of immunoglobulin genes
- 2002
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Doctoral thesis (other academic/artistic)abstract
- In this thesis, the structure and the expression of immunoglobulin (Ig) light chain genes were studied in rainbow trout and including an evolutionary perspective. A novel Ig light chain locus (IgL2) was identified and characterized. As an expansion of this study, the genomic organization of two Ig light chains was settled in genomic clones, some putative transcription regulatory elements were identified and the expression of L1 and L2 was studied in several tissues. In order to study expression of L1 and L2 at the protein level, monoclonal antibodies were generated, using DNA immunization. The contribution of different IgL isotypes in the antibody response against a fish rhabdovirus was investigated. This study demonstrated that the variability of L1 and L2 was modified in different manners. Genomic clones for a third trout light chain (IgL3) were isolated, and the sequence of the putative promoter regions of the three isotypes were compared. The L1 and L3 promoters have a classical Ig promoter structure (i.e. with TATA-box, E-box, and octamer) whereas the L2 promoter lacks the typical features of an Ig promoter. The IgL2 promoter region contained a κ-Y motif and an E-box. Cell transfection studies using different deletion constructs demonstrated that the κ-Y element drives the transcriptional activity of L2 promoter. Both the L1 and L2 promoters can cooperate with a B cell specific enhancer from cod, suggesting that common transcription factors are used.L1 is most similar to the κ isotype found in mammals whereas L2 shows many features that deviate from this branch and the λ branch and forms a separate branch. The similarity between the L1C and L2C of trout Ig is about 30%. Thus, a sequence comparison of L1C regions with L3C regions shows a continuous transition in identity percentages, whereas the L2C appears not closely related to any C segment from another isotype. These results pave the way for a comprehensive understanding of the evolution, regulation and functions of light chains in a primitive vertebrate the rainbow trout, and other fish species.
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