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1.	Thery, C, et al. (author) Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines 2018 In: Journal of extracellular vesicles. - : Wiley. - 2001-3078. ; 7:1, s. 1535750- Journal article (peer-reviewed)
2.	Crowley, S. D., et al. (author) Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis 2009 In: J Clin Invest. - 1558-8238 .- 1558-8238 .- 0021-9738. ; 119:4, s. 943-53 Journal article (peer-reviewed)abstract Studies in humans and animal models indicate a key contribution of angiotensin II to the pathogenesis of glomerular diseases. To examine the role of type 1 angiotensin (AT1) receptors in glomerular inflammation associated with autoimmune disease, we generated MRL-Faslpr/lpr (lpr) mice lacking the major murine type 1 angiotensin receptor (AT1A); lpr mice develop a generalized autoimmune disease with glomerulonephritis that resembles SLE. Surprisingly, AT1A deficiency was not protective against disease but instead substantially accelerated mortality, proteinuria, and kidney pathology. Increased disease severity was not a direct effect of immune cells, since transplantation of AT1A-deficient bone marrow did not affect survival. Moreover, autoimmune injury in extrarenal tissues, including skin, heart, and joints, was unaffected by AT1A deficiency. In murine systems, there is a second type 1 angiotensin receptor isoform, AT1B, and its expression is especially prominent in the renal glomerulus within podocytes. Further, expression of renin was enhanced in kidneys of AT1A-deficient lpr mice, and they showed evidence of exaggerated AT1B receptor activation, including substantially increased podocyte injury and expression of inflammatory mediators. Administration of losartan, which blocks all type 1 angiotensin receptors, reduced markers of kidney disease, including proteinuria, glomerular pathology, and cytokine mRNA expression. Since AT1A-deficient lpr mice had low blood pressure, these findings suggest that activation of type 1 angiotensin receptors in the glomerulus is sufficient to accelerate renal injury and inflammation in the absence of hypertension.
3.	Woolf, Anthony D., et al. (author) Clinical advances – from bench to bedside 2020 In: Best Practice and Research: Clinical Rheumatology. - : Elsevier BV. - 1521-6942. ; 34:5 Research review (peer-reviewed)
4.	Mobarrez, F, et al. (author) Increased levels of microvesicles containing nuclear molecules and immunoglobulins in patients with systemic lupus erythematosus 2016 In: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. - 0300-9742. ; 45, s. 38-39 Conference paper (other academic/artistic)
5.	Mobarrez, F, et al. (author) Microvesicles Containing Nucleic Acids and Expressing Immunoglobulins and HMGB1 Are Abundant in Patients with Systemic Lupus Erythematosus 2015 In: ARTHRITIS & RHEUMATOLOGY. - 2326-5191. ; 67 Conference paper (other academic/artistic)
6.	Mobarrez, F., et al. (author) The Expression Of Microparticles In The Blood Of Patients With Systemic Lupus Erythematosus (SLE) : Phenotypic Characterization And Clinical Associations 2016 In: Clinical and Experimental Rheumatology. - 0392-856X .- 1593-098X. ; 34:4, s. S70-S70 Journal article (peer-reviewed)
7.	Mobarrez, F, et al. (author) The Expression of Mitochondrial Molecules in Microparticle Immune Complexes in the Blood of Patients with Systemic Lupus Erythematosus 2017 In: ARTHRITIS & RHEUMATOLOGY. - 2326-5191. ; 69 Conference paper (other academic/artistic)

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Type of publication: conference paper (3); journal article (3); research review (1)

Type of content: peer-reviewed (4); other academic/artistic (3)

Author/Editor: Gunnarsson, I (4); Svenungsson, E (4); Mobarrez, F (4); Gustafsson, J (3); Wallen, H (3); Zickert, A (3); show more...; Chen, S. (1); Jenster, G (1); Antoniou, A (1); Park, J (1); Sharma, S. (1); Kim, H. S. (1); Yin, H. (1); Das, S. (1); Rak, J. (1); Schneider, R. (1); Krause, M. (1); Moller, A (1); Larsson, Anders (1); Ortiz, A (1); Weiss, DJ (1); Leszczynska, A. (1); Ostrowski, M. (1); Xu, J (1); Sahoo, S. (1); Buch, S (1); Nejsum, P (1); Ruiz, P (1); Gabrielsson, S (1); Lötvall, Jan, 1956 (1); Cheng, L (1); Shiba, K (1); Wheelock, AM (1); Woolf, Anthony D (1); Zheng, L (1); Kaur, S (1); Scott, A (1); Nawaz, Muhammad (1); Witwer, KW (1); Hunt, S (1); Chen, CC (1); Gardiner, C (1); Akesson, Kristina E. (1); Lim, R (1); Mullier, F (1); Baharvand, H (1); Huber, V. (1); Zhao, ZZ (1); Anderson, JD (1); Ivanova, A (1); show less...

University: Karolinska Institutet (5); University of Gothenburg (2); Uppsala University (2); Lund University (2)

Language: English (7)

Research subject (UKÄ/SCB): Medical and Health Sciences (4); Natural sciences (1)

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