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1.	Domenici, MR, et al. (author) Neuronal adenosine A2A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease 2018 In: Purinergic signalling. - : Springer Science and Business Media LLC. - 1573-9546 .- 1573-9538. ; 14:3, s. 235-243 Journal article (peer-reviewed)
2.	Agid, Y, et al. (author) How can drug discovery for psychiatric disorders be improved? 2007 In: Nature reviews. Drug discovery. - : Springer Science and Business Media LLC. - 1474-1776 .- 1474-1784. ; 6:3, s. 189-201 Journal article (peer-reviewed)
3.	Blaveri, E, et al. (author) Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours 2010 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 5:9, s. e12596- Journal article (peer-reviewed)
4.	Carboni, L, et al. (author) Depression-Associated Gene Negr1-Fgfr2 Pathway Is Altered by Antidepressant Treatment 2020 In: Cells. - : MDPI AG. - 2073-4409. ; 9:8 Journal article (peer-reviewed)abstract The Negr1 gene has been significantly associated with major depression in genetic studies. Negr1 encodes for a cell adhesion molecule cleaved by the protease Adam10, thus activating Fgfr2 and promoting neuronal spine plasticity. We investigated whether antidepressants modulate the expression of genes belonging to Negr1-Fgfr2 pathway in Flinders sensitive line (FSL) rats, in a corticosterone-treated mouse model of depression, and in mouse primary neurons. Negr1 and Adam10 were the genes mostly affected by antidepressant treatment, and in opposite directions. Negr1 was down-regulated by escitalopram in the hypothalamus of FSL rats, by fluoxetine in the hippocampal dentate gyrus of corticosterone-treated mice, and by nortriptyline in hippocampal primary neurons. Adam10 mRNA was increased by nortriptyline administration in the hypothalamus, by escitalopram in the hippocampus of FSL rats, and by fluoxetine in mouse dorsal dentate gyrus. Similarly, nortriptyline increased Adam10 expression in hippocampal cultures. Fgfr2 expression was increased by nortriptyline in the hypothalamus of FSL rats and in hippocampal neurons. Lsamp, another IgLON family protein, increased in mouse dentate gyrus after fluoxetine treatment. These findings suggest that Negr1-Fgfr2 pathway plays a role in the modulation of synaptic plasticity induced by antidepressant treatment to promote therapeutic efficacy by rearranging connectivity in corticolimbic circuits impaired in depression.
5.	Carboni, L, et al. (author) Early-life stress and antidepressants modulate peripheral biomarkers in a gene-environment rat model of depression 2010 In: Progress in neuro-psychopharmacology & biological psychiatry. - : Elsevier BV. - 1878-4216 .- 0278-5846. ; 34:6, s. 1037-1048 Journal article (peer-reviewed)
6.	Carboni, L, et al. (author) Proteomic analysis of hippocampus and frontal cortex in a rat model of depression with gene-environment interaction and antidepressant treatment 2006 In: EUROPEAN NEUROPSYCHOPHARMACOLOGY. - 0924-977X. ; 16, s. S336-S337 Conference paper (other academic/artistic)
7.	Chiodi, V, et al. (author) Striatal adenosine-cannabinoid receptor interactions in rats over-expressing adenosine A2A receptors 2016 In: Journal of neurochemistry. - : Wiley. - 1471-4159 .- 0022-3042. ; 136:5, s. 907-917 Journal article (peer-reviewed)
8.	Eriksson, TM, et al. (author) Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration 2012 In: Molecular psychiatry. - : Springer Science and Business Media LLC. - 1476-5578 .- 1359-4184. ; 17:2, s. 173-184 Journal article (peer-reviewed)
9.	Eriksson, TM, et al. (author) Glutamatergic deficits and differential antidepressant regulation in rat model of depression 2011 In: EUROPEAN NEUROPSYCHOPHARMACOLOGY. - 0924-977X. ; 21, s. S410-S410 Conference paper (other academic/artistic)
10.	Fuxe, K, et al. (author) Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease 2003 In: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 1526-632X .- 0028-3878. ; 61:11 Suppl 6, s. S19-23 Journal article (peer-reviewed)

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Result 1-10 of 28

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Type of publication: journal article (20); conference paper (8)

Type of content: peer-reviewed (20); other academic/artistic (8)

Author/Editor: Popoli, M (20); Mathe, AA (13); Mallei, A (12); Racagni, G (10); Fuxe, K (8); Musazzi, L (8); show more...; Popoli, P (8); El Khoury, A (7); Domenici, E (7); Carboni, L (7); Giambelli, R (7); FERRE, S (6); Mathe, A (4); Pezzola, A (4); Barbiero, VS (4); Rowan, MJ (4); Svenningsson, P (3); Ogren, SO (3); Spedding, M (3); Torvinen, M (3); Piubelli, C (3); Tardito, D (3); Ryan, BK (3); Li, L. (2); Schaefer, J. (2); Papadopoulos, N (2); Agnati, LF (2); Franco, R (2); Eriksson, TM (2); Lauria, M (2); Gruber, SHM (2); Bader, M (2); Aitchison, KJ (2); Terasmaa, A (2); Razzoli, M (2); Muller, CE (2); Gruber, S (2); Chiodi, V (2); Ferrante, A (2); Armida, M (2); Domenici, MR (2); Gruber, SH (2); Delagrange, P (2); Reggio, R (2); Vogelstein, B (2); Ptak, J (2); Anwyl, R (2); Kinde, I. (2); Silliman, N. (2); Dobbyn, L. (2); show less...

University: Karolinska Institutet (27); University of Gothenburg (1)

Language: English (28)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

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