| 1. |
- Ademuyiwa, Adesoji O., et al.
(author)
-
Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
-
In: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
-
Journal article (peer-reviewed)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
|
|
| 2. |
- Falster, Daniel, et al.
(author)
-
AusTraits, a curated plant trait database for the Australian flora
- 2021
-
In: Scientific Data. - : Nature Portfolio. - 2052-4463. ; 8:1
-
Journal article (peer-reviewed)abstract
- We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation. AusTraits contains curated and harmonised individual- and species-level measurements coupled to, where available, contextual information on site properties and experimental conditions. This article provides information on version 3.0.2 of AusTraits which contains data for 997,808 trait-by-taxon combinations. We envision AusTraits as an ongoing collaborative initiative for easily archiving and sharing trait data, which also provides a template for other national or regional initiatives globally to fill persistent gaps in trait knowledge.
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- Alexander, Peter, et al.
(author)
-
Assessing uncertainties in land cover projections
- 2017
-
In: Global Change Biology. - : Wiley. - 1354-1013. ; 23:2, s. 767-781
-
Journal article (peer-reviewed)abstract
- Understanding uncertainties in land cover projections is critical to investigating land-based climate mitigation policies, assessing the potential of climate adaptation strategies and quantifying the impacts of land cover change on the climate system. Here, we identify and quantify uncertainties in global and European land cover projections over a diverse range of model types and scenarios, extending the analysis beyond the agro-economic models included in previous comparisons. The results from 75 simulations over 18 models are analysed and show a large range in land cover area projections, with the highest variability occurring in future cropland areas. We demonstrate systematic differences in land cover areas associated with the characteristics of the modelling approach, which is at least as great as the differences attributed to the scenario variations. The results lead us to conclude that a higher degree of uncertainty exists in land use projections than currently included in climate or earth system projections. To account for land use uncertainty, it is recommended to use a diverse set of models and approaches when assessing the potential impacts of land cover change on future climate. Additionally, further work is needed to better understand the assumptions driving land use model results and reveal the causes of uncertainty in more depth, to help reduce model uncertainty and improve the projections of land cover.
|
|
| 6. |
- Hoyle, Aiden, et al.
(author)
-
Weapons of mass division : Sputnik Latvia's Russophobia narratives and testing the rejectionidentification model in Russian speakers in Latvia
- 2024
-
In: Political Psychology. - 0162-895X .- 1467-9221.
-
Journal article (peer-reviewed)abstract
- The effects of exposure to Russian propaganda have long been feared; however, academic research examining responses is scarce. This study aims to investigate the responses of Russian speakers in Latvia to a narrative propagated by the Kremlin-sponsored media outlet Sputnik Latvia that narrates Latvian government policy as Russophobic. The potential to entrench existing ethnopolitical divisions has been highlighted as a possible effect of Russian speakers consuming this narration. We adopt a comprehensive, mixed-method research approach, where we first provide an analysis of the content of Sputnik Latvia's Russophobia narrative in its recent output. Then, using this analysis, we examine how Russian-speaking participants respond to this content in a preregistered survey experiment and a focus group. Theoretically, we orient around the rejection-identification model. This predicts individuals to generally experience lower well-being after perceiving group-based discrimination, but that embracing the stigmatized identity can help maintain well-being despite this perceived devaluation. Our results showed that even brief exposure to Sputnik Latvia's Russophobia narrative led to higher levels of perceived discrimination and group identification in Russian speakers. However, we found no significant effects on well-being, which deviates from extant literature on discrimination. We discuss the reasons for this and suggest future directions.
|
|
| 7. |
- Jung, Minyong, et al.
(author)
-
The AGORA High-resolution Galaxy Simulations Comparison Project. V. Satellite Galaxy Populations in a Cosmological Zoom-in Simulation of a Milky Way-Mass Halo
- 2024
-
In: Astrophysical Journal. - 0004-637X. ; 964:2
-
Journal article (peer-reviewed)abstract
- We analyze and compare the satellite halo populations at z ∼ 2 in the high-resolution cosmological zoom-in simulations of a 1012 M ⊙ target halo (z = 0 mass) carried out on eight widely used astrophysical simulation codes (Art-I, Enzo, Ramses, Changa, Gadget-3, Gear, Arepo-t, and Gizmo) for the AGORA High-resolution Galaxy Simulations Comparison Project. We use slightly different redshift epochs near z = 2 for each code (hereafter “z ∼ 2”) at which the eight simulations are in the same stage in the target halo’s merger history. After identifying the matched pairs of halos between the CosmoRun simulations and the DMO simulations, we discover that each CosmoRun halo tends to be less massive than its DMO counterpart. When we consider only the halos containing stellar particles at z ∼ 2, the number of satellite galaxies is significantly fewer than that of dark matter halos in all participating AGORA simulations and is comparable to the number of present-day satellites near the Milky Way or M31. The so-called “missing satellite problem” is fully resolved across all participating codes simply by implementing the common baryonic physics adopted in AGORA and the stellar feedback prescription commonly used in each code, with sufficient numerical resolution (≲100 proper pc at z = 2). We also compare other properties such as the stellar mass-halo mass relation and the mass-metallicity relation. Our work highlights the value of comparison studies such as AGORA, where outstanding problems in galaxy formation theory are studied simultaneously on multiple numerical platforms.
|
|
| 8. |
- Locke, Adam E, et al.
(author)
-
Genetic studies of body mass index yield new insights for obesity biology.
- 2015
-
In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 197-401
-
Journal article (peer-reviewed)abstract
- Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.
|
|
| 9. |
- Strawn, Clayton, et al.
(author)
-
The AGORA High-resolution Galaxy Simulations Comparison Project. VI. Similarities and Differences in the Circumgalactic Medium
- 2024
-
In: Astrophysical Journal. - 0004-637X. ; 962:1
-
Journal article (peer-reviewed)abstract
- We analyze the circumgalactic medium (CGM) for eight commonly-used cosmological codes in the AGORA collaboration. The codes are calibrated to use identical initial conditions, cosmology, heating and cooling, and star formation thresholds, but each evolves with its own unique code architecture and stellar feedback implementation. Here, we analyze the results of these simulations in terms of the structure, composition, and phase dynamics of the CGM. We show properties such as metal distribution, ionization levels, and kinematics are effective tracers of the effects of the different code feedback and implementation methods, and as such they can be highly divergent between simulations. This is merely a fiducial set of models, against which we will in the future compare multiple feedback recipes for each code. Nevertheless, we find that the large parameter space these simulations establish can help disentangle the different variables that affect observable quantities in the CGM, e.g., showing that abundances for ions with higher ionization energy are more strongly determined by the simulation’s metallicity, while abundances for ions with lower ionization energy are more strongly determined by the gas density and temperature.
|
|
| 10. |
- Svedberg, Anna, et al.
(author)
-
The effects of formation aids on flow properties of cellulosic fibrous suspensions
-
Other publication (other academic/artistic)abstract
- The effects of high molecular weight anionic polymers on the flow behaviour of fibrous suspensions were studied using phase flow encoded nuclear magnetic resonance imaging (MRI). We examined whether formation improvements by high molecular weight polymers correlate with turbulence damping. Flow imaging measurements and pressure drop analysis were performed for water and fibrous suspensions (0.5 % consistency) with and without polymer added, at different mean velocities (1.0, 1.2 and 1.4 m/s). Our results are consistent with drag reduction of turbulent flows by additives. The results further show how fibres and high molecular weight anionic polymers reduce the drag of turbulent flows, in terms of damping turbulence fluctuations (as determined by signal intensities) and flow profile characteristics. The turbulence damping effect was also manifested through a decrease of pressure drop. When fibres and polymers were used together, we found that the drag was reduced by amounts greater than the sum of the two independent effects. The reinforced effect on drag reduction can be explained by the fact that fibres and polymers act differently with the turbulent flow. The study also reveals the influence of the polymer structure (from linear to highly structured). The overall results indicate that turbulence damping and paper formation improvements by the addition of high molecular weight polymers (Class II formation aids) are strongly correlated. This work can lead to better specification of retention aid systems and design of modern head boxes used for papermaking.
|
|
