| 1. |
|
|
| 2. |
- Ayub, Rabia, et al.
(author)
-
High-Value Chemicals from Electrocatalytic Depolymerization of Lignin : Challenges and Opportunities
- 2022
-
In: International Journal of Molecular Sciences. - : MDPI. - 1661-6596 .- 1422-0067. ; 23:7
-
Journal article (peer-reviewed)abstract
- Lignocellulosic biomass is renewable and one of the most abundant sources for the production of high-value chemicals, materials, and fuels. It is of immense importance to develop new efficient technologies for the industrial production of chemicals by utilizing renewable resources. Lignocellulosic biomass can potentially replace fossil-based chemistries. The production of fuel and chemicals from lignin powered by renewable electricity under ambient temperatures and pressures enables a more sustainable way to obtain high-value chemicals. More specifically, in a sustainable biorefinery, it is essential to valorize lignin to enhance biomass transformation technology and increase the overall economy of the process. Strategies regarding electrocatalytic approaches as a way to valorize or depolymerize lignin have attracted significant interest from growing scientific communities over the recent decades. This review presents a comprehensive overview of the electro-catalytic methods for depolymerization of lignocellulosic biomass with an emphasis on untargeted depolymerization as well as the selective and targeted mild synthesis of high-value chemicals. Elec-trocatalytic cleavage of model compounds and further electrochemical upgrading of bio-oils are discussed. Finally, some insights into current challenges and limitations associated with this approach are also summarized. © 2022 by the authors.
|
|
| 3. |
- Raheel, Ahmad, et al.
(author)
-
SYNTHESIS, ANTIMICROBIAL ACTIVITY, UREASE INHIBITION AND MOLECULAR DOCKING STUDIES OF NEW PROLINE LINKED THIOUREA DERIVATIVES
- 2020
-
In: Revue roumaine de chimie. - : Romanian Academy - Revue Roumaine De Chimie. - 0035-3930. ; 65:9, s. 783-788
-
Journal article (peer-reviewed)abstract
- A series of new thiourea based carboxylic acids (I-a-I-e) were synthesized and characterized by elemental analysis, FTIR and NMR (H-1 and C-13) spectroscopy. They were preliminary bioassayed for their antibacterial, anifungal and urease inhibition activities. Molecular docking simulations were carried out to determine the probable binding mode of the synthesized compounds. The bioassay results showed that some of titled compounds exhibited encouraging results.
|
|
| 4. |
- Raheel, Kiran, et al.
(author)
-
Design and Performance Evaluation of Orthogonally Polarized Corporate Feed MIMO Antenna Array for Next-Generation Communication System
- 2024
-
In: IEEE Access. - : Institute of Electrical and Electronics Engineers (IEEE). - 2169-3536. ; 12, s. 30382-30397
-
Journal article (peer-reviewed)abstract
- This study presents a novel, compact, diamond-shaped Multiple Input Multiple Output (MIMO) antenna system for 5G wireless communication. The proposed MIMO antenna system encompasses an array configuration, with each array unit comprising two antenna elements. The array elements are then orthogonally oriented making it a dual-port MIMO antenna system. The system is printed on a commercially available Rogers 5880, characterized by a permittivity ( epsilon(r) ) of 2.2 and a loss tangent (tan( delta) ) of 0.0009. The overall dimensions of the MIMO antenna system are 26 x 16 x 0.254 mm(3), operating in an mm-wave band with a frequency spectrum spanning from 26.2 to 34.2 GHz. The single antenna element exhibited a gain of 3.8 dBi and is then improved up to 7.6 dBi with two elements array arrangement. The system exhibited satisfactory MIMO characteristics with a maximum diversity gain of 10 dB, an envelope correlation coefficient of less than 0.0005, and an impressive 25 dB isolation between the antenna elements. Moreover, the proposed MIMO antenna array consistently maintained a radiation efficiency exceeding 90% across the entire desired frequency spectrum. Measurements were conducted with fabricated prototypes to validate the simulation results and were found in good agreement. The remarkable features of the proposed MIMO antenna system, such as compact size, wide bandwidth, good efficiency, and satisfactory gain values make it a promising candidate for 5G millimeter-wave wireless communication networks.
|
|
| 5. |
- Taj, Muhammad Babar, et al.
(author)
-
Exploring novel fluorine-rich fuberidazole derivatives as hypoxic cancer inhibitors : Design, synthesis, pharmacokinetics, molecular docking, and DFT evaluations
- 2023
-
In: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 18:2
-
Journal article (peer-reviewed)abstract
- Sixteen fuberidazole derivatives as potential new anticancer bioreductive prodrugs were prepared and characterized. The in vitro anticancer potential was examined to explore their cytotoxic properties by employing apoptosis, DNA damage, and proliferation tests on chosen hypoxic cancer cells. Eight substances (Compound 5a, 5c, 5d, 5e, 5g, 5h, 5i, and 5m) showed promising cytotoxicity values compared to the standard control. The potential of compounds was also examined through in silico studies (against human serum albumin), including chem-informatics, to understand the structure-activity relationship (SAR), pharmacochemical strength, and the mode of interactions responsible for their action. The DFT calculations revealed that only the 5b compound showed the lowest ΔET (2.29 eV) while 5i showed relatively highest βtot (69.89 x 10–31 esu), highest αave (3.18 x 10–23 esu), and dipole moment (6.49 Debye). This study presents a novel class of fuberidazole derivatives with selectivity toward hypoxic cancer cells.
|
|
