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- Lupattelli, A., et al.
(author)
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Medication use in pregnancy: a cross-sectional, multinational web-based study
- 2014
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In: BMJ Open. - : BMJ. - 2044-6055. ; 4:2
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Journal article (peer-reviewed)abstract
- Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants Pregnant women and new mothers with children less than 1year of age. Primary and secondary outcome measures Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.
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- Rieutord, M, et al.
(author)
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A simulation of solar convection at supergranulation scale
- 2002
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In: Nuovo Cimento C. Colloquia on Physics. - 1124-1896. ; 25:5-6, s. 523-528
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Journal article (peer-reviewed)abstract
- We present here numerical simulations of surface solar convection which cover a box of 30 x 30 x 3.2 Mm(3) with a resolution of 315 x 315 x 82, which is used to investigate the dynamics of scales larger than granulation. No structure resembling supergranulation is present; possibly higher Reynolds numbers (i.e. higher numerical resolution), or magnetic fields, or greater depth are necessary. The results also show interesting aspects of granular dynamics which are briefly presented, like extensive p-mode ridges in the k-w diagram and a ringlike distribution of horizontal vorticity around granules. At large scales, the horizontal velocity is much larger than the vertical velocity and the vertical motion is dominated by p-mode oscillations.
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