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| 2. |
- Rosseel, Liesbeth, et al.
(author)
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Contemporary European practice in transcatheter aortic valve implantation: results from the 2022 European TAVI Pathway Registry.
- 2023
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In: Frontiers in cardiovascular medicine. - 2297-055X. ; 10
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Journal article (peer-reviewed)abstract
- A steep rise in the use of transcatheter aortic valve implantation (TAVI) for the management of symptomatic severe aortic stenosis occurred. Minimalist TAVI procedures and streamlined patient pathways within experienced Heart Valve Centres are designed to overcome the challenges of ever-increasing procedural volume.The 2022 European TAVI Pathway Survey aims to describe contemporary TAVI practice across Europe.Between October and December 2022, TAVI operators from 32 European countries were invited to complete an online questionnaire regarding their current practice.Responses were available from 147 TAVI centres in 26 countries. In 2021, the participating centres performed a total number of 27,223 TAVI procedures, with a mean of 185 TAVI cases per centre (median 138; IQR 77-194). Treatment strategies are usually (87%) discussed at a dedicated Heart Team meeting. Transfemoral TAVI is performed with local anaesthesia only (33%), with associated conscious sedation (60%), or under general anaesthesia (7%). Primary vascular access is percutaneous transfemoral (99%) with secondary radial access (52%). After uncomplicated TAVI, patients are transferred to a high-, medium-, or low-care unit in 28%, 52%, and 20% of cases, respectively. Time to discharge is day 1 (12%), day 2 (31%), day 3 (29%), or day 4 or more (28%).Reported adoption of minimalist TAVI techniques is common among European TAVI centres, but rates of next-day discharge remain low. This survey highlights the significant progress made in refining TAVI treatment and pathways in recent years and identifies possible areas for further improvement.
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| 4. |
- Bergshoeff, E. A., et al.
(author)
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A consistent limit of 11D Supergravity
- 2023
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In: Corfu Summer Institute 2022 "School and Workshops on Elementary Particle Physics and Gravity", CORFU 2022. - : Sissa Medialab Srl.
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Conference paper (peer-reviewed)abstract
- Motivated by old and new developments in non-relativistic string theory, we show that there exists a consistent non-relativistic limit of eleven-dimensional supergravity. Before taking the limit we give a short review of the underlying Membrane Newton-Cartan geometry. This geometry is a particular extension of the Newton-Cartan geometry in the sense that the two nondegenerate metrics of Newton-Cartan geometry (one to measure time intervals and another one to measure spatial distances) are replaced by two nondegenerate metrics of rank 3 and rank 8, respectively. An important role in describing this geometry and in the consistency of the limit is played by the so-called intrinsic torsion tensor components. These are the components of the torsion tensor that are independent of the spin-connection. After expanding the action of eleven-dimensional supergravity as a power series of a contraction parameter, we show how the different divergences that arise when taking the limit can be tamed. We furthermore show how the divergences that arise in expanding the supersymmetry rules can be controlled by imposing a supersymmetric set of constraints. This leads to a Membrane Newton-Cartan supergravity theory where the Newton potential can be identified with the component of the 3-form of eleven-dimensional supergravity that points in the three directions corresponding to the rank 3 degenerate metric.
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| 5. |
- Bergshoeff, E. A., et al.
(author)
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Generalized Newton-Cartan geometries for particles and strings
- 2023
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In: Classical and quantum gravity. - : IOP Publishing. - 0264-9381 .- 1361-6382. ; 40:7
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Journal article (peer-reviewed)abstract
- We discuss the generalized Newton-Cartan geometries that can serve as gravitational background fields for particles and strings. In order to enable us to define affine connections that are invariant under all the symmetries of the structure group, we describe torsionful geometries with independent torsion tensors. A characteristic feature of the non-Lorentzian geometries we consider is that some of the torsion tensors are so-called 'intrinsic torsion' tensors. Setting some components of these intrinsic torsion tensors to zero leads to constraints on the geometry. For both particles and strings, we discuss various such constraints that can be imposed consistently with the structure group symmetries. In this way, we reproduce several results in the literature.
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| 6. |
- Chemissany, W., et al.
(author)
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Black holes in supergravity and integrability
- 2010
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In: Journal of High Energy Physics (JHEP). - 1126-6708 .- 1029-8479. ; :9, s. 80-
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Journal article (peer-reviewed)abstract
- Stationary black holes of massless supergravity theories are described by certain geodesic curves on the target space that is obtained after dimensional reduction over time. When the target space is a symmetric coset space we make use of the group-theoretical structure to prove that the second order geodesic equations are integrable in the sense of Liouville, by explicitly constructing the correct amount of Hamiltonians in involution. This implies that the Hamilton-Jacobi formalism can be applied, which proves that all such black hole solutions, including non-extremal solutions, possess a description in terms of a (fake) superpotential. Furthermore, we improve the existing integration method by the construction of a Lax integration algorithm that integrates the second order equations in one step instead of the usual two step procedure. We illustrate this technology with a specific example.
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| 7. |
- De Wilde, J., et al.
(author)
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Is the Community as method approach gender sensitive? : Client and treatment characteristics in European Therapeutic Communities. Results of the BIOMED II (IPTRP) project.
- 2006
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In: International Journal of Social Welfare. - : Wiley. - 1369-6866 .- 1468-2397. ; 15:2, s. 150-161
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Journal article (peer-reviewed)abstract
- The BIOMED II project, ‘Improving Psychiatric Treatment in Residential Programmes for Newly Dependent Groups through Relapse Prevention’, provided a large database of characteristics of men and women in European therapeutic communities (TCs). One of the aims of the project was to improve the treatment of ‘emerging dependency groups’ through better assessment. Although American TC research has shown that there are important differences between men and women that should be taken into account when organising treatment, the BIOMED project failed to report on gender differences. This article tries to fill this gap by presenting an overview of the gender differences in the TC clients and lists the characteristics of the participating European TCs. The two overviews are given for each country separately. Descriptive methods were used. The authors discuss whether the TC programme considers the differences between men and women and whether the ‘community as method’ approach is gender sensitive.
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| 8. |
- Needleman, IG, et al.
(author)
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Improving the effectiveness of tobacco use cessation (TUC)
- 2010
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In: International Dental Journal. - : FDI/World dental press. - 0020-6539 .- 1875-595X. ; 60:1, s. 50-59
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Journal article (peer-reviewed)abstract
- This paper includes an update of a Cochrane systematic review on tobacco use cessation (TUC) in dental settings as well as narrative reviews of possible approaches to TUC and a more detailed discussion of referral for specialist TUC services. On the basis of these reviews we conclude that interventions for tobacco users in the dental setting increase the odds of quitting tobacco. However, the evidence is derived largely from patients using smokeless tobacco. Pharmacotherapy (such as nicotine replacements, bupropion and varenicline) is recommended for TUC in medical settings but has received little assessment in dental applications, although such evidence to date is promising. Whether the dental setting or referral to specialist TUC services is the most effective strategy to help people to quit tobacco use is unclear. An effective specialist service providing best available TUC care alone may not be the answer. Clearly, such services should be both accessible and convenient for tobacco users. Closer integration of specialist services with referrers would also be advantageous in order to guide and support oral health professionals make their referral and to maximise follow-up of referred tobacco users. Future research direction may consider investigating the most effective components of TUC in the dental settings and community-based trials should be a priority. Pharmacotherapy, particularly nicotine replacement therapy, should be more widely examined in dental settings. We also recommend that various models of referral to external and competent in-house TUC specialist services should be examined with both experimental and qualitative approaches. In addition to overall success of TUC, important research questions include facilitators and barriers to TUC in dental settings, preferences for specialist referral, and experiences of tobacco users attempting to quit, with dental professionals or specialist services, respectively.
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