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- Kullman, Eric, et al.
(author)
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Covered versus uncovered self-expandable nitinol stents in the palliative treatment of malignant distal biliary obstruction: results from a randomized, multicenter study
- 2010
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In: GASTROINTESTINAL ENDOSCOPY. - : Elsevier Science B. V., Amsterdam. - 0016-5107 .- 1097-6779. ; 72:5, s. 915-923
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Journal article (peer-reviewed)abstract
- Background: Covered biliary metal stents have been developed to prevent tumor ingrowth. Previous comparative studies are limited and often include few patients. Objective: To compare differences in stent patency, patient survival, and complication rates between covered and uncovered nitinol stents in patients with malignant biliary obstruction. Design: Randomized, multicenter trial conducted between January 2006 and October 2008. Setting: Ten sites serving a total catchment area of approximately 2.8 million inhabitants. Patients: A total of 400 patients with unresectable distal malignant biliary obstruction. Interventions: ERCP with insertion of covered or uncovered metal stent. Follow-up conducted monthly for symptoms indicating stent obstruction. Main Outcome Measurements: Time to stent failure, survival time, and complication rate. Results: The patient survival times were 116 days (interquartile range 242 days) and 174 days (interquartile range 284 days) in the covered and uncovered stent groups, respectively (P = .320). The first quartile stent patency time was 154 days in the covered stent group and 199 days in the uncovered stent group (P = .326). There was no difference in the incidence of pancreatitis or cholecystitis between the 2 groups. Stent migration occurred in 6 patients (3%) in the covered group and in no patients in the uncovered group (P = .030). Limitations: Randomization was not blinded. Conclusions: There were no significant differences in stent patency time, patient survival time, or complication rates between covered and uncovered nitinol metal stents in the palliative treatment of malignant distal biliary obstruction. However, covered stents migrated significantly more often compared with uncovered stents, and tumor ingrowth was more frequent in uncovered stents.
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| 6. |
- Lööf, Lars, et al.
(author)
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Behandlingsprogram vid ascites. Rekommendationer fran Svensk forening for gastroenterologi och gastrointestinal endoskopi
- 2001
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In: Läkartidningen. - 0023-7205. ; 98:49, s. 5649-5655
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Journal article (peer-reviewed)abstract
- As ascites is related to liver cirrhosis in 80% of the patients, the present therapeutic guidelines are focused on ascites in liver cirrhosis. A combination of spironolactone and furosemide is recommended as first line therapy in patients with mild to moderate ascites and is effective in 90% of patients. In patients with pronounced or tense ascites, first line treatment is total paracentesis with intravenous infusion of human albumin as colloid replacement. Maintenance therapy for the prevention of recurrent ascites is based on spironolactone with or without furosemide. The indications for peritoneovenous shunt, or transjugular intrahepatic stent-shunt (TIPSS), are limited and only recommended in strictly selected patients with refractory ascites. Ascites in liver cirrhosis is a symptom of advanced liver disease, and liver transplantation should always be considered in eligible patients.
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| 7. |
- Rogers, Paul, et al.
(author)
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Moderniserad dagsljusstandard
- 2018
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Reports (other academic/artistic)abstract
- This report is the account of SBUF project 13209 “Moderniserad dagsljusstandard” (Modernized daylight standard). This is a continuation of the SBUF project 12966 “Förstudie dagsljusstandard” (Pre-study daylight standard) published in 2015. SBUF and the Swedish Energy Agency are the two sources of this project’s funding. The task has been to freely describe and interpret history, day-to-day and future development needs for daylight in buildings within the framework of the Swedish National Board of Housing, Building and Planning. The project has been a feasibility study in order to design a proposal on how to proceed towards creating an improved and modernized interpretation of BBR section 6: 322. The ultimate goal is a daylight standard applicable to the construction industry and functioning.
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