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  • Inoue, Juliana, et al. (author)
  • Plasmodium falciparum Plasmepsin 2 Duplications, West Africa
  • 2018
  • In: Emerging Infectious Diseases. - : Centers for Disease Control and Prevention. - 1080-6040 .- 1080-6059. ; 24:8, s. 1591-1593
  • Journal article (peer-reviewed)abstract
    • Dihydroartemisinin/piperaquine (DHA/PPQ) is increasingly deployed as antimalaria drug in Africa. We report the detection in Mali of Plasmodium falciparum infections carrying plasmepsin 2 duplications (associated with piperaquine resistance) in 7/65 recurrent infections within 2 months after DHA/PPQ treatment. These findings raise concerns about the long-term efficacy of DHA/PPQ treatment in Africa.
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