↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Savai R) "

Search: WFRF:(Savai R)

Result 1-4 of 4

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Elwakeel, E, et al. (author) Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis 2022 In: Cancer research. - 1538-7445. ; 82:7, s. 1380-1395 Journal article (peer-reviewed)
2.	Donzelli, J, et al. (author) Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer 2021 In: Journal of extracellular vesicles. - : Wiley. - 2001-3078. ; 10:12, s. e12143- Journal article (peer-reviewed)
3.	Saul, MJ, et al. (author) miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction 2019 In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. - 1530-6860. ; 33:6, s. 6933-6947 Journal article (peer-reviewed)
4.	Zheng, X, et al. (author) Metabolism in tumour-associated macrophages: a quid pro quo with the tumour microenvironment 2020 In: European respiratory review : an official journal of the European Respiratory Society. - : European Respiratory Society (ERS). - 1600-0617. ; 29:157 Journal article (peer-reviewed)abstract Lung cancer is the leading cause of death from cancer worldwide. Recent studies demonstrated that the tumour microenvironment (TME) is pivotal for tumour progression, providing multiple targeting opportunities for therapeutic strategies. As one of the most abundant stromal cell types in the TME, tumour-associated macrophages (TAMs) exhibit high plasticity. Malignant cells alter their metabolic profiles to adapt to the limited availability of oxygen and nutrients in the TME, resulting in functional alteration of TAMs. The metabolic features of TAMs are strongly associated with their functional plasticity, which further impacts metabolic profiling in the TME and contributes to tumourigenesis and progression. Here, we review the functional determination of the TME by TAM metabolic alterations, including glycolysis as well as fatty acid and amino acid metabolism, which in turn are influenced by environmental changes. Additionally, we discuss metabolic reprogramming of TAMs to a tumouricidal phenotype as a potential antitumoural therapeutic strategy.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-4 of 4

Refine your search

Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Savai, R (4); Seeger, W (2); Saul, MJ (2); Thomas, D. (1); Wheelock, CE (1); Bruno, A. (1); show more...; Sala, G. (1); Larsson, K (1); Guenther, A. (1); Jakobsson, PJ (1); Han, YY (1); Stein, S. (1); Zheng, X (1); Idborg, H (1); Korotkova, M (1); Baumann, I. (1); Fleming, I (1); Weigert, A. (1); Popp, R. (1); STEINHILBER, D (1); Donnini, S (1); Pullamsetti, SS (1); Grimminger, F (1); Mansouri, S (1); Terzuoli, E (1); Donzelli, J (1); Proestler, E (1); Riedel, A (1); Nevermann, S (1); Hertel, B (1); Gattenlohner, S (1); Elwakeel, E (1); Bruggemann, M (1); Wagih, J (1); Lityagina, O (1); Elewa, MAF (1); Fromel, T (1); Nicolas, AM (1); Schreiber, Y (1); Gradhand, E (1); Nusing, R (1); Steinmetz-Spah, J (1); Fokas, E (1); Greten, FR (1); Zarnack, K (1); Brune, B (1); Suess, B (1); Contursi, A. (1); Ottinger, SM (1); Raouf, J (1); show less...

University: Karolinska Institutet (4)

Language: English (4)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view