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Sökning: WFRF:(Schaefer Christiane)

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1.
  • Raschmann, Simone-Christiane, et al. (författare)
  • Zur Bedeutung der Turfanfunde
  • 2013
  • Ingår i: <em>Wege zum geistigen Erbe der Menschheit. </em>. - Göttingen : Akademie der Wissenschaften zu Göttingen. ; , s. 67-73
  • Bokkapitel (refereegranskat)
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2.
  • Beecham, Ashley H, et al. (författare)
  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
  • 2013
  • Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:11, s. 1353-60
  • Tidskriftsartikel (refereegranskat)abstract
    • Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0 × 10(-4)). In a replication phase, we combined these data with previous genome-wide association study (GWAS) data from an independent 14,802 subjects with multiple sclerosis and 26,703 healthy controls. In these 80,094 individuals of European ancestry, we identified 48 new susceptibility variants (P < 5.0 × 10(-8)), 3 of which we found after conditioning on previously identified variants. Thus, there are now 110 established multiple sclerosis risk variants at 103 discrete loci outside of the major histocompatibility complex. With high-resolution Bayesian fine mapping, we identified five regions where one variant accounted for more than 50% of the posterior probability of association. This study enhances the catalog of multiple sclerosis risk variants and illustrates the value of fine mapping in the resolution of GWAS signals.
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6.
  • Knight, Kevin, et al. (författare)
  • The Copiale Cipher
  • 2011
  • Konferensbidrag (refereegranskat)abstract
    • The Copiale cipher is a 105-page enciphered book dated 1866. We describe the features of the book and the method by which we deciphered it.
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7.
  • Knight, Kevin, et al. (författare)
  • The Secrets of the Copiale Cipher
  • 2011
  • Ingår i: Research into Freemasonry and Fraternalism. - 1757-2460. ; 2:2, s. 314-324
  • Tidskriftsartikel (refereegranskat)abstract
    • The Copiale Cipher is a 105-page, hand-written encrypted manuscript from the mid-eighteenth century. Its code was cracked and the text was deciphered by using modern computational technology combined with philological methods. We describe the book, the features of the text, and give a brief summary of the method by which we deciphered it. Finally, we present the content and the secret society, namely the Oculists, who were hiding behind the cipher. 
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8.
  • Niklasson, Bo, et al. (författare)
  • Development of type 1 diabetes in wild bank voles associated with islet autoantibodies and the novel ljungan virus.
  • 2003
  • Ingår i: International journal of experimental diabesity research. - : Hindawi Limited. ; 4:1, s. 35-44
  • Tidskriftsartikel (refereegranskat)abstract
    • Wild bank voles (Clethrionomys glareolus) may develop diabetes in laboratory captivity. The aim of this study was to test whether bank voles develop type 1 diabetes in association with Ljungan virus. Two groups of bank voles were analyzed for diabetes, pancreas histology, autoantibodies to glutamic acid decarboxylase (GAD65), IA-2, and insulin by standardized radioligand-binding assays as well as antibodies to in vitro transcribed and translated Ljungan virus antigens. Group A represented 101 trapped bank voles, which were screened for diabetes when euthanized within 24 hours of capture. Group B represented 67 bank voles, which were trapped and kept in the laboratory for 1 month before being euthanized. Group A bank voles did not have diabetes. Bank voles in group B (22/67; 33%) developed diabetes due to specific lysis of pancreatic islet beta cells. Compared to nondiabetic group B bank voles, diabetic animals had increased levels of GAD65 (P < .0001), IA-2 (P < .0001), and insulin (P
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9.
  • Odyniec, Pawel, 1976- (författare)
  • Engaging Advaita : Conceptualising liberating knowledge in the face of Western modernity
  • 2018
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • This dissertation is a study of modern Indian philosophy. It examines three engaging articulations of the Advaitic notion of liberating knowledge or brahmajñāna provided by three prominent Indian philosophers of the twentieth century, namely, Badrīnāth Śukla (1898-1988), Krishnachandra Bhattacharyya (1875-1949), and Sarvepalli Radhakrishnan (1888-1975). Particular attention is paid to the existing relation between their distinctive conceptualisations of liberating knowledge and the doxastic attitudes that these authors professed towards the Sanskrit intellectual past of South Asia and the presence of the Western Other.In the main, it argues that the profound differences to be found, on the one hand, in Śukla’s elucidation of this key Advaitic notion and, on the other, in Bhattacharyya’s and Radhakrishnan’s take on the same, betray their commitment to two radically different doxastic attitudes. Classifying these into (a) non-dialogical and (b) dialogical in relation to the Western Other as well as into (c) exegetic and (d) hermeneutic in relation to the Sanskrit intellectual past of South Asia, it contends that, in comparison to the conceptual scheme and the parameters of intelligibility that shaped and underpinned the precolonial Advaitic discourse on brahmajñāna in Sanskrit, there is a certain kind of epistemic discontinuity in the dialogical cum hermeneutic stance taken by Bhattacharyya and Radhakrishnan that is not to be found in the non-dialogical cum exegetic engagement enacted by Śukla. It suggests that this particular sort of discontinuity, absent as it is from Śukla’s elucidation of the process of knowing Brahman, reflects the far-reaching commitment of Krishnachandra Bhattacharyya and Sarvepalli Radhakrishnan to appropriate the precolonial Advaitic notion of liberating knowledge hermeneutically and to conceptualise it in the face of Western modernity, that is, rendering it meaningful in terms and within the parameters of intelligibility of the Western Other in order to contest what they took to be a troublesome predicament of Western modernity.By examining their ways of engaging with the Advaitic notion of liberating knowledge, this dissertation contributes to the on-going debate about the nature and the driving forces of modern Indian philosophy.
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