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1.	Singh, K. P., et al. (author) Clinical standards for the management of adverse effects during treatment for TB 2023 In: The International Journal of Tuberculosis and Lung Disease. - : International Union Against Tuberculosis and Lung Disease. - 1027-3719 .- 1815-7920. ; 27:7, s. 506-519 Journal article (peer-reviewed)abstract BACKGROUND: Adverse effects (AE) to TB treatment cause morbidity, mortality and treatment interruption. The aim of these clinical standards is to encourage best practise for the diagnosis and management of AE.METHODS: 65/81 invited experts participated in a Delphi process using a 5-point Likert scale to score draft standards.RESULTS: We identified eight clinical standards. Each person commencing treatment for TB should: Standard 1, be counselled regarding AE before and during treatment; Standard 2, be evaluated for factors that might increase AE risk with regular review to actively identify and manage these; Standard 3, when AE occur, carefully assessed and possible allergic or hypersensitiv-ity reactions considered; Standard 4, receive appropriate care to minimise morbidity and mortality associated with AE; Standard 5, be restarted on TB drugs after a serious AE according to a standardised protocol that includes active drug safety monitoring. In addition: Standard 6, healthcare workers should be trained on AE including how to counsel people undertaking TB treatment, as well as active AE monitoring and management; Standard 7, there should be active AE monitoring and reporting for all new TB drugs and regimens; and Standard 8, knowledge gaps identified from active AE monitoring should be systematically addressed through clinical research.CONCLUSION: These standards provide a person -centred, consensus-based approach to minimise the impact of AE TB treatment.
2.	Ahmad, N, et al. (author) Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis 2018 In: Lancet (London, England). - 1474-547X. ; 392:10150, s. 821-834 Journal article (peer-reviewed)
3.	Mitnick, CD, et al. (author) Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda 2016 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 11:5, s. e0155968- Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Lange, C. (2); Singla, R (2); Centis, R (2); D'Ambrosio, L (2); Kim, H. Y. (1); Hu, Y. (1); show more...; Ahmad, N. (1); Lee, M (1); Oren, E (1); Svensson, Elin, 1985 ... (1); Bonnet, M (1); Carvalho, I (1); Bang, D (1); Benedetti, A (1); Lan, ZY (1); Li, PZ (1); Menzies, D (1); Migliori, GB (1); Ndjeka, N (1); Khan, FA (1); Gu, S. (1); Zignol, M (1); Nahid, P (1); de Vries, G (1); Hughes, J (1); Guglielmetti, L (1); Bruchfeld, J (1); Borisov, S. (1); Tabarsi, P (1); Ahuja, SD (1); Akkerman, OW (1); Alffenaar, JWC (1); Anderson, LF (1); Baghaei, P (1); Barry, PM (1); Bastos, ML (1); Behera, D (1); Bisson, GP (1); Boeree, MJ (1); Brode, SK (1); Brust, JCM (1); Cai, Y (1); Caumes, E (1); Cegielski, JP (1); Chan, PC (1); Chan, ED (1); Chang, KC (1); Charles, M (1); Cirule, A (1); Dalcolmo, MP (1); show less...

University: Karolinska Institutet (3); Uppsala University (1)

Language: English (3)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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