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Sökning: WFRF:(Simunic B.)

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  • Keramidas, Michail E., et al. (författare)
  • Respiratory muscle endurance training : Effect on normoxic and hypoxic exercise performance
  • 2010
  • Ingår i: European Journal of Applied Physiology. - : Springer Science and Business Media LLC. - 1439-6319 .- 1439-6327. ; 108:4, s. 759-769
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to investigate the effect of respiratory muscle endurance training on endurance exercise performance in normoxic and hypoxic conditions. Eighteen healthy males were stratified for age and aerobic capacity; and randomly assigned either to the respiratory muscle endurance training (RMT = 9) or to the control training group (CON = 9). Both groups trained on a cycle-ergometer 1 h day(-1), 5 days per week for a period of 4 weeks at an intensity corresponding to 50% of peak power output. Additionally, the RMT group performed a 30-min specific endurance training of respiratory muscles (isocapnic hyperpnea) prior to the cycle ergometry. Pre, Mid, Post and 10 days after the end of training period, subjects conducted pulmonary function tests (PFTs), maximal aerobic tests in normoxia ((V) over dotO(2max)NOR), and in hypoxia ((V) over dotO(2max)HYPO; F(I)O(2) = 0.12); and constant-load tests at 80% of (V) over dotO(2max)NOR in normoxia (CLT(NOR)), and in hypoxia (CLT(HYPO)). Both groups enhanced (V) over dotO(2max)NOR (CON: +13.5%; RMT: +13.4%), but only the RMT group improved (V) over dotO(2max)HYPO Post training (CON: -6.5%; RMT: +14.2%). Post training, the CON group increased peak power output, whereas the RMT group had higher values of maximum ventilation. Both groups increased CLT(NOR) duration (CON: +79.9%; RMT: +116.6%), but only the RMT group maintained a significantly higher CLT(NOR) 10 days after training (CON: +56.7%; RMT: +91.3%). CLT(HYPO) remained unchanged in both groups. Therefore, the respiratory muscle endurance training combined with cycle ergometer training enhanced aerobic capacity in hypoxia above the control values, but did not in normoxia. Moreover, no additional effect was obtained during constant-load exercise.
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  • Mekjavic, I.B., et al. (författare)
  • Altitude Acclimatization
  • 2008
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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  • Mekjavic, I.B., et al. (författare)
  • Evaluation of hypoxic training protocols
  • 2009
  • Ingår i: Aviation, Space and Environmental Medicine. - 0095-6562 .- 1943-4448. ; 80:3, s. 289-289
  • Tidskriftsartikel (refereegranskat)abstract
    • Acute exposure to high altitude impairs performance, both aerobic and psychomotor. Consequently preparation of personnel to be deployed to high attitude regions should incorporate a programme of altitude acclimatisation.  The aim of the present study was to evaluate the effect of several training programmes on sea level and altitude performance: Live low-Train High (LL-TH), Intermittent Hypoxic Training (IHT), Respiratory Muscle Training (RMT), and Sleep High-Train Low (SH-TL).
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  • Rittweger, Jörn, et al. (författare)
  • Bone loss in the lower leg during 35 days of bed rest is predominantly from the cortical compartment
  • 2009
  • Ingår i: Bone. - : Elsevier BV. - 8756-3282 .- 1873-2763. ; 44:4, s. 612-618
  • Tidskriftsartikel (refereegranskat)abstract
    • Immobilization-induced bone loss is usually greater in the epiphyses than in the diaphyses. The larger fraction of trabecular bone in the epiphyses than in the diaphyses offers an intuitive explanation to account for this phenomenon. However, recent evidence contradicts this notion and suggests that immobilization-induced bone loss from the distal tibia epiphysis is mainly from the cortical compartment. The aim of this study was to establish whether this pattern of bone loss was a general rule during immobilization. We monitored various skeletal sites with different tissue composition during 5 weeks of immobilization. Ten healthy male volunteers with mean age of 24.3 years (SD 2.6 years) underwent strict horizontal bed rest. Bone scans were obtained during baseline data collection, at the end of bed rest and after 14 days of recovery by peripheral Quantitative Computed Tomography (pQCT). Sectional images were obtained from the distal tibia epiphysis (at 4% of the tibia's length), from the diaphysis (at 38%), from the proximal metaphysis (at 93%) and from the proximal epiphysis (at 98%), as well as from the distal femur epiphysis (at 4% of the femur's length) and from the patella. Relative bone losses were largest at the patella, where they amounted to -3.2% (SD 1.8%, p<0.001) of the baseline values, and smallest at the tibia diaphysis, where they amounted to -0.7% (SD 1.0%, p=0.019). The relative losses were generally larger from cortical than from trabecular compartments (p=0.004), and whilst all skeletal sites depicted such cortical losses, substantial trabecular losses were found only from the proximal tibia epiphysis. Results confirm that the differential losses from the various skeletal sites cannot be explained on the basis of trabecular vs. cortical tissue composition differences, but that endocortical circumference can account for the different amounts of bone loss in the tibia. The present study therefore supports the suggestion of the subendocortical layer as a transitional zone, which can readily be transformed into trabecular bone in response to immobilization. The latter will lead to cortical thinning, a factor that has been associated with the risk of fracture and with osteoarthritis.
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