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- Aloysius, TA, et al.
(author)
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Plasma Cholesterol- and Body Fat-Lowering Effects of Chicken Protein Hydrolysate and Oil in High-Fat Fed Male Wistar Rats
- 2022
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In: Nutrients. - : MDPI AG. - 2072-6643. ; 14:24
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Journal article (peer-reviewed)abstract
- Rest raw materials provide a new source of bioactive dietary ingredients, and this study aimed to determine the health effects of diets with chicken protein hydrolysate (CPH) and chicken oil (CO) generated from deboned chicken meat. Male Wistar rats (n = 56) were divided into seven groups in three predefined sub-experiments to study the effects of protein source (casein, chicken fillet, pork fillet, and CPH), the dose-effect of CPH (50% and 100% CPH), and the effects of combining CPH and CO. Rats were fed high-fat diets for 12 weeks, and casein and chicken fillet were used as controls in all sub-experiments. While casein, chicken-, or pork fillet diets resulted in similar weight gain and plasma lipid levels, the CPH diet reduced plasma total cholesterol. This effect was dose dependent and accompanied with the reduced hepatic activities of acetyl-CoA carboxylase and fatty acid synthase. Further, rats fed combined CPH and CO showed lower weight gain, and higher hepatic mitochondrial fatty acid oxidation, plasma L-carnitine, short-chain acylcarnitines, TMAO, and acetylcarnitine/palmitoylcarnitine. Thus, in male Wistar rats, CPH and CO lowered plasma cholesterol and increased hepatic fatty acid oxidation compared to whole protein diets, pointing to potential health-beneficial bioactive properties of these processed chicken rest raw materials.
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Framtidens Digitala Lärande i Skolan (FDLIS) : Ett unikt samverkansprojekt
- 2021. - 1
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Editorial collection (peer-reviewed)abstract
- Skolan står inför en stor utmaning i att möta det digitaliserade samhället, där nya former för lärande och kommunikation ständigt utvecklas. Den snabba utvecklingen av det digitala och globala samhället ställer krav på både lärares och elevers kunskaper och förmågor. Samtidigt skapar tekniken nya pedagogiska möjligheter. Det finns ett stort behov av att problematisera hur skolans praktik påverkas och kan vara en del av den av den tekniska utvecklingen.I denna bok presenterar vi ett flertal rapporter från forsknings- och samverkansprojektet Framtidens Digitala Lärande i Skolan (FDLIS). Boken är skriven av både forskare och personal inom skola och förskola, och utgör därmed ett unikt bidrag i att problematisera framtidens digitala lärande i skolan från olika perspektiv.
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| 6. |
- Fransson, Agneta, 1964, et al.
(author)
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Impact of sea-ice processes on the carbonate system and ocean acidification at the ice-water interface of the Amundsen Gulf, Arctic Ocean
- 2013
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In: Journal of Geophysical Research - Oceans. - 0148-0227 .- 2156-2202. ; 118:12, s. 7001-7023
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Journal article (peer-reviewed)abstract
- From sea-ice formation in November 2007 to onset of ice melt in May 2008, we studied the carbonate system in first-year Arctic sea ice, focusing on the impact of calcium-carbonate (CaCO3) saturation states of aragonite (ΩAr) and calcite (ΩCa) at the ice-water interface (UIW). Based on total inorganic carbon (CT) and total alkalinity (AT), and derived pH, CO2, carbonate ion ([CO3 2-]) concentrations and Ω, we investigated the major drivers such as brine rejection, CaCO3 precipitation, bacterial respiration, primary production and CO2-gas flux in sea ice, brine, frost flowers and UIW. We estimated large variability in sea-ice CT at the top, mid, and bottom ice. Changes due to CaCO3 and CO2-gas flux had large impact on CT in the whole ice core from March to May, bacterial respiration was important at the bottom ice during all months, and primary production in May. It was evident that the sea-ice processes had large impact on UIW, resulting in a five times larger seasonal amplitude of the carbonate system, relative to the upper 20 m. During ice formation, [CO2] increased by 30 μmol kg-1, [CO3 2-] decreased by 50 μmol kg-1, and the ΩAr decreased by 0.8 in the UIW due to CO2-enriched brine from solid CaCO3. Conversely, during ice melt, [CO3 2-] increased by 90 μmol kg -1 in the UIW, and Ω increased by 1.4 between March and May, likely due to CaCO3 dissolution and primary production. We estimated that increased ice melt would lead to enhanced oceanic uptake of inorganic carbon to the surface layer. Key Points Evidence of impact of sea-ice dynamics on CO2 system at ice-water interface Larger variability of CO 2 system in upper 2 m than upper 20 m from solid CaCO3 Ice melt promote enhanced oceanic CO2 uptake © 2013. American Geophysical Union. All Rights Reserved.
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| 7. |
- Grauman, Åsa, 1982-, et al.
(author)
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Good general health and lack of family history influence the underestimation of cardiovascular risk : A cross sectional study
- 2021
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In: European Journal of Cardiovascular Nursing. - : Oxford University Press. - 1474-5151 .- 1873-1953. ; 20:7, s. 676-683
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Journal article (peer-reviewed)abstract
- Aims Underestimation of cardiovascular risk may interfere with prevention of cardiovascular diseases (CVDs). We investigate whether general health and family history of myocardial infarction (MI) are associated with underestimation of perceived cardiovascular risk, and if the participants' calculated risk modifies that association.Methods and results The analysis sample consisted of 526 individuals, 50-64 years old, from a population-based cohort study. Information on general health (poor/fairly good, good, and very good/excellent), family history of MI, and self-perceived risk relative to others of similar age and sex were collected though a web-based survey. Participants were categorized into underestimation (n = 162, 31%), accurate estimation (n = 222, 42%), and overestimation (n = 142, 27%) of cardiovascular risk by comparing calculated Systematic Coronary Risk Estimation (SCORE) with self-perceived risk. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for underestimation vs. accurate estimation of cardiovascular risk were computed using logistic regression (n = 384). Very good general health (OR 2.60, 95% CI 1.10-6.16) and lack of family history (OR 2.27, 95% CI 1.24-4.18) were associated with underestimation of cardiovascular risk. The associations were modified by the participants' calculated risk level; the association was stronger for high-risk individuals; without family history OR 22.57 (95% CI 6.17-82.54); with very good/excellent health OR 15.78 (95% CI 3.73-66.87).Conclusion A good general health and the lack of family CVD history can obscure the presence of other risk factors and lead to underestimation of cardiovascular risk, especially for high-risk individuals. It is, therefore, crucial to address the fact that the development of CV disease may be silent and multifactorial.
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| 9. |
- Matsuda, Ryo, et al.
(author)
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Multipotent versus differentiated cell fate selection in the developing Drosophila airways
- 2015
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In: eLIFE. - 2050-084X. ; 4
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Journal article (peer-reviewed)abstract
- Developmental potentials of cells are tightly controlled at multiple levels. The embryonic Drosophila airway tree is roughly subdivided into two types of cells with distinct developmental potentials: a proximally located group of multipotent adult precursor cells (P-fate) and a distally located population of more differentiated cells (D-fate). We show that the GATA-family transcription factor (TF) Grain promotes the P-fate and the POU-homeobox TF Ventral veinless (Vvl/Drifter/U-turned) stimulates the D-fate. Hedgehog and receptor tyrosine kinase (RTK) signaling cooperate with Vvl to drive the D-fate at the expense of the P-fate while negative regulators of either of these signaling pathways ensure P-fate specification. Local concentrations of Decapentaplegic/BMP, Wingless/Wnt, and Hedgehog signals differentially regulate the expression of D-factors and P-factors to transform an equipotent primordial field into a concentric pattern of radially different morphogenetic potentials, which gradually gives rise to the distal-proximal organization of distinct cell types in the mature airway.
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- Mianehrow, Hanieh, et al.
(author)
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Strong reinforcement effects in 2D cellulose nanofibril–graphene oxide (CNF–GO) nanocomposites due to GO-induced CNF ordering
- 2020
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In: Journal of Materials Chemistry A. - 2050-7488 .- 2050-7496. ; 8:34, s. 17608-17620
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Journal article (peer-reviewed)abstract
- Nanocomposites from native cellulose with low 2D nanoplatelet content are of interest as sustainable materials combining functional and structural performance. Cellulose nanofibril–graphene oxide (CNF–GO) nanocomposite films are prepared by a physical mixing–drying method, with a focus on low GO content, the use of very large GO platelets (2–45 μm) and nanostructural characterization using synchrotron X-ray source for WAXS and SAXS. These nanocomposites can be used as transparent coatings, strong films or membranes, as gas barriers or in laminated form. CNF nanofibrils with random in-plane orientation, form a continuous non-porous matrix with GO platelets oriented in-plane. GO reinforcement mechanisms in CNF are investigated, and relationships between nanostructure and suspension rheology, mechanical properties, optical transmittance and oxygen barrier properties are investigated as a function of GO content. A much higher modulus reinforcement efficiency is observed than in previous polymer–GO studies. The absolute values for modulus and ultimate strength are as high as 17 GPa and 250 MPa at a GO content as small as 0.07 vol%. The remarkable reinforcement efficiency is due to improved organization of the CNF matrix; and this GO-induced mechanism is of general interest for nanostructural tailoring of CNF-2D nanoplatelet composites.
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