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1.	Asano, T, et al. (author) X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 2021 In: Science immunology. - : American Association for the Advancement of Science (AAAS). - 2470-9468. ; 6:62 Journal article (peer-reviewed)abstract TLR7 and plasmacytoid dendritic cells are essential for type I IFN–dependent immunity to SARS-CoV-2 in the lungs.
2.	Fyhrquist, N, et al. (author) Microbe-host interplay in atopic dermatitis and psoriasis 2019 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 4703- Journal article (peer-reviewed)abstract Despite recent advances in understanding microbial diversity in skin homeostasis, the relevance of microbial dysbiosis in inflammatory disease is poorly understood. Here we perform a comparative analysis of skin microbial communities coupled to global patterns of cutaneous gene expression in patients with atopic dermatitis or psoriasis. The skin microbiota is analysed by 16S amplicon or whole genome sequencing and the skin transcriptome by microarrays, followed by integration of the data layers. We find that atopic dermatitis and psoriasis can be classified by distinct microbes, which differ from healthy volunteers microbiome composition. Atopic dermatitis is dominated by a single microbe (Staphylococcus aureus), and associated with a disease relevant host transcriptomic signature enriched for skin barrier function, tryptophan metabolism and immune activation. In contrast, psoriasis is characterized by co-occurring communities of microbes with weak associations with disease related gene expression. Our work provides a basis for biomarker discovery and targeted therapies in skin dysbiosis.
3.	Fyhrquist, N, et al. (author) Microbe-host interplay in atopic dermatitis and psoriasis 2016 In: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. - 0300-9475. ; 83:5, s. 380-381 Conference paper (other academic/artistic)
4.	Lefevre-Utile, A, et al. (author) Transcriptome-based identification of novel endotypes in adult atopic dermatitis 2022 In: Allergy. - : Wiley. - 1398-9995 .- 0105-4538. ; 77:5, s. 1486-1498 Journal article (peer-reviewed)
5.	Oláh, P, et al. (author) Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation 2022 In: Journal of dermatological science. - 1873-569X. ; 106:3, s. 132-140 Journal article (peer-reviewed)
6.	Olah, P, et al. (author) Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation 2022 In: Journal of dermatological science. - : Elsevier BV. - 1873-569X .- 0923-1811. ; 106:3, s. 132-140 Journal article (peer-reviewed)
7.	Ottman, N, et al. (author) Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites 2021 In: Allergy. - : Wiley. - 1398-9995 .- 0105-4538. ; 76:4, s. 1173-1187 Journal article (peer-reviewed)

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Type of publication: journal article (6); conference paper (1)

Type of content: peer-reviewed (6); other academic/artistic (1)

Author/Editor: Barker, J (5); Kere, J (5); Alenius, H (5); Andersson, B. (5); Fyhrquist, N (5); Olah, P (5); show more...; Homey, B (5); Greco, D (4); Alexander, H (4); Skoog, T (3); Serra, A (2); Weidinger, S (2); Rodriguez, E (2); Zhang, Q. (1); Zhang, Y. (1); Bryceson, YT (1); Hansmann, B. (1); Casanova, JL (1); Abolhassani, H (1); Biondi, A (1); Zhang, P (1); Bergman, P. (1); Katayama, S (1); Novelli, G (1); Hammarstrom, L (1); Yan, L. (1); Khan, T. (1); Notarangelo, LD (1); Pan-Hammarstrom, Q (1); Boisson, B (1); Keles, S (1); Su, HC (1); Bastard, P (1); Materna, M (1); Marr, N (1); Ata, M (1); Al-Ali, F (1); Béziat, V (1); Zhang, SY (1); Karisola, P (1); Brodin, P (1); Lifton, RP (1); Tresoldi, C (1); Smith, CIE (1); Suomela, S (1); Franco, JL (1); Allende, LM (1); Ekwall, Olov, 1968 (1); Sinkko, H (1); van den Bogaard, EH (1); show less...

University: Karolinska Institutet (7); University of Gothenburg (1)

Language: English (7)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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