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Träfflista för sökning "WFRF:(Stafford M) "

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Enumeration	Reference	Cover	Find
1.	2017 swepub:Mat__t
2.	Glasbey, JC, et al. (author) 2021 swepub:Mat__t
3.	Adamina, M, et al. (author) The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study 2022 In: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. - : Wiley. - 1463-1318. ; 24:6, s. 708-726 Journal article (peer-reviewed)
4.	Ong, KL, et al. (author) Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 2023 In: Lancet (London, England). - 1474-547X .- 0140-6736. ; 402:10397, s. 203-234 Journal article (peer-reviewed)
5.	Goetghebuer, T, et al. (author) Time to Switch to Second-line Antiretroviral Therapy in Children With Human Immunodeficiency Virus in Europe and Thailand 2018 In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. - : Oxford University Press (OUP). - 1537-6591. ; 66:4, s. 594-603 Journal article (peer-reviewed)
6.	Hochman, JS, et al. (author) Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial 2019 In: JAMA cardiology. - : American Medical Association (AMA). - 2380-6591 .- 2380-6583. ; 4:3, s. 273-286 Journal article (peer-reviewed)
7.	Van Bavel, JJ, et al. (author) Author Correction: National identity predicts public health support during a global pandemic 2022 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 13:1, s. 1949- Journal article (other academic/artistic)
8.	Postmus, I., et al. (author) Meta-analysis of genome-wide association studies of HDL cholesterol response to statins 2016 In: Journal of Medical Genetics. - : BMJ. - 0022-2593 .- 1468-6244. ; 53:12, s. 835-45 Journal article (peer-reviewed)abstract Background In addition to lowering low density lipoprotein cholesterol (LDL-C), statin therapy also raises high density lipoprotein cholesterol (HDL-C) levels. Interindividual variation in HDL-C response to statins may be partially explained by genetic variation. Methods and results We performed a meta-analysis of genome-wide association studies (GWAS) to identify variants with an effect on statin-induced high density lipoprotein cholesterol (HDL-C) changes. The 123 most promising signals with p<1x10(-4) from the 16 769 statin-treated participants in the first analysis stage were followed up in an independent group of 10 951 statin-treated individuals, providing a total sample size of 27 720 individuals. The only associations of genome-wide significance (p<5x10(-8)) were between minor alleles at the CETP locus and greater HDL-C response to statin treatment. Conclusions Based on results from this study that included a relatively large sample size, we suggest that CETP may be the only detectable locus with common genetic variants that influence HDL-C response to statins substantially in individuals of European descent. Although CETP is known to be associated with HDL-C, we provide evidence that this pharmacogenetic effect is independent of its association with baseline HDL-C levels.
9.	Callaway, EM, et al. (author) A multimodal cell census and atlas of the mammalian primary motor cortex 2021 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 598:7879, s. 86-102 Journal article (peer-reviewed)abstract Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network (BICCN). This was achieved by coordinated large-scale analyses of single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved single-cell transcriptomes, morphological and electrophysiological properties and cellular resolution input–output mapping, integrated through cross-modal computational analysis. Our results advance the collective knowledge and understanding of brain cell-type organization1–5. First, our study reveals a unified molecular genetic landscape of cortical cell types that integrates their transcriptome, open chromatin and DNA methylation maps. Second, cross-species analysis achieves a consensus taxonomy of transcriptomic types and their hierarchical organization that is conserved from mouse to marmoset and human. Third, in situ single-cell transcriptomics provides a spatially resolved cell-type atlas of the motor cortex. Fourth, cross-modal analysis provides compelling evidence for the transcriptomic, epigenomic and gene regulatory basis of neuronal phenotypes such as their physiological and anatomical properties, demonstrating the biological validity and genomic underpinning of neuron types. We further present an extensive genetic toolset for targeting glutamatergic neuron types towards linking their molecular and developmental identity to their circuit function. Together, our results establish a unifying and mechanistic framework of neuronal cell-type organization that integrates multi-layered molecular genetic and spatial information with multi-faceted phenotypic properties.
10.	Lagou, V, et al. (author) Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability 2021 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1, s. 995- Journal article (other academic/artistic)abstract A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21276-3

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Type of publication: journal article (49); conference paper (3); other publication (1); research review (1); book chapter (1)

Type of content: peer-reviewed (48); other academic/artistic (6); pop. science, debate, etc. (1)

Author/Editor: Stafford, J (7); Willerslev, Eske (5); Liu, Yongmei (5); Evans, J. (4); Saavedra, J (4); Rudan, Igor (4); show more...; Rasmussen, Morten (4); van Duijn, Cornelia ... (4); Nielsen, Rasmus (4); Orlando, Ludovic (4); Munroe, Patricia B. (4); Harris, Tamara B (4); Loos, Ruth J F (4); Chen, S. (3); Banerjee, S. (3); Kumar, A. (3); Costa, M. (3); Khan, A. (3); Lee, M (3); Sharma, P. (3); Richards, M. (3); Santos, R. (3); Groop, Leif (3); Lind, Lars (3); McNeill, A (3); Elhadi, M (3); Singh, S (3); Ahmed, A (3); Murphy, C (3); Bianchini, M (3); Baldini, E (3); Martin, E (3); McCarthy, Mark I (3); Ridker, Paul M. (3); Chasman, Daniel I. (3); Scott, A (3); Rotter, Jerome I. (3); Nyberg, Fredrik, 196 ... (3); Olaison, Lars, 1949 (3); Anstrom, Kevin J. (3); Skedung, Lisa (3); Allentoft, Morten E. (3); Rasmussen, Simon (3); Rutland, Mark (3); Palmer, Colin N. A. (3); Hoen, B. (3); Miro, J. M. (3); Gilbert, M. Thomas P ... (3); Jakobsson, Mattias (3); Eiriksdottir, Gudny (3); show less...

University: Karolinska Institutet (26); Uppsala University (14); University of Gothenburg (9); Stockholm University (9); Royal Institute of Technology (7); Lund University (6); show more...; Stockholm School of Economics (3); Kristianstad University College (2); Umeå University (2); Linköping University (2); RISE (2); Linnaeus University (1); Högskolan Dalarna (1); Swedish Museum of Natural History (1); Swedish University of Agricultural Sciences (1); show less...

Language: English (57)

Research subject (UKÄ/SCB): Medical and Health Sciences (19); Natural sciences (17); Social Sciences (8); Engineering and Technology (3); Humanities (2)

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