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Träfflista för sökning "WFRF:(Stamatopoulos A.) "

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  • Chatzikonstantinou, T, et al. (author)
  • COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study
  • 2021
  • In: Leukemia. - : Springer Science and Business Media LLC. - 1476-5551 .- 0887-6924. ; 35:12, s. 3444-3454
  • Journal article (peer-reviewed)abstract
    • Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to Coronavirus disease 2019 (COVID-19) due to age, disease, and treatment-related immunosuppression. We aimed to assess risk factors of outcome and elucidate the impact of CLL-directed treatments on the course of COVID-19. We conducted a retrospective, international study, collectively including 941 patients with CLL and confirmed COVID-19. Data from the beginning of the pandemic until March 16, 2021, were collected from 91 centers. The risk factors of case fatality rate (CFR), disease severity, and overall survival (OS) were investigated. OS analysis was restricted to patients with severe COVID-19 (definition: hospitalization with need of oxygen or admission into an intensive care unit). CFR in patients with severe COVID-19 was 38.4%. OS was inferior for patients in all treatment categories compared to untreated (p < 0.001). Untreated patients had a lower risk of death (HR = 0.54, 95% CI:0.41–0.72). The risk of death was higher for older patients and those suffering from cardiac failure (HR = 1.03, 95% CI:1.02–1.04; HR = 1.79, 95% CI:1.04–3.07, respectively). Age, CLL-directed treatment, and cardiac failure were significant risk factors of OS. Untreated patients had a better chance of survival than those on treatment or recently treated.
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  • Result 1-10 of 125
Type of publication
journal article (99)
conference paper (22)
research review (3)
other publication (1)
Type of content
peer-reviewed (68)
other academic/artistic (57)
Author/Editor
Stamatopoulos, K (89)
Ghia, P (57)
Agathangelidis, A (39)
Pospisilova, S (37)
Davi, F (35)
Anagnostopoulos, A (31)
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Rosenquist, R. (29)
Davis, Z (27)
Belessi, C (27)
Scarfo, L (26)
Oscier, D. (26)
Hadzidimitriou, A (24)
Stamatopoulos, Kosta ... (24)
Rosenquist, Richard (21)
Chatzidimitriou, A (21)
Plevova, K. (19)
Rossi, D (18)
Campo, E (17)
Darzentas, N (16)
Chiorazzi, N (16)
Langerak, AW (14)
Stalika, E. (14)
Gaidano, G. (14)
Stilgenbauer, S. (14)
Mansouri, L. (13)
Mansouri, Larry (13)
Giudicelli, V (13)
Psomopoulos, F (13)
Baliakas, Panagiotis (13)
Minga, E. (12)
Xochelli, A. (12)
Sutton, Lesley-Ann (12)
Sutton, LA (12)
Sutton, L. A. (11)
Panagiotidis, P. (11)
Nguyen-Khac, F. (11)
Juliusson, G (10)
Smedby, KE (10)
Rosenquist, Richard ... (10)
Catherwood, M. (9)
Schuh, A (9)
Puiggros, A. (9)
Kotaskova, J. (9)
Delgado, J. (8)
Vlachonikola, E (8)
Ranghetti, P (8)
Chatzouli, M. (8)
Trentin, L. (8)
Parker, H. (8)
Athanasiadou, A. (8)
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University
Karolinska Institutet (83)
Uppsala University (56)
Lund University (4)
Umeå University (3)
Örebro University (1)
Linköping University (1)
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Linnaeus University (1)
RISE (1)
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Language
English (125)
Research subject (UKÄ/SCB)
Medical and Health Sciences (47)
Natural sciences (6)
Engineering and Technology (1)

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