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1.	Ahmad, T, et al. (author) Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries 2016 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 117:5, s. 601- Journal article (peer-reviewed)
2.	Ahmad, T, et al. (author) In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study 2017 In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. - : Elsevier BV. - 1532-2157 .- 0748-7983. ; 43:12, s. 2324-2332 Journal article (peer-reviewed)
3.	Ahmad, T, et al. (author) Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery 2017 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 119:2, s. 258-266 Journal article (peer-reviewed)
4.	Walton, E, et al. (author) Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa 2019 In: Molecular neurobiology. - : Springer Science and Business Media LLC. - 1559-1182 .- 0893-7648. ; 56:7, s. 5146-5156 Journal article (peer-reviewed)
5.	Hibar, Derrek P., et al. (author) Novel genetic loci associated with hippocampal volume 2017 In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8 Journal article (peer-reviewed)abstract The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (r(g) = -0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.
6.	van Essen, TA, et al. (author) Correction to: Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study 2019 In: Acta neurochirurgica. - : Springer Science and Business Media LLC. - 0942-0940 .- 0001-6268. ; 161:3, s. 451-455 Journal article (other academic/artistic)
7.	Satizabal, Claudia L., et al. (author) Genetic architecture of subcortical brain structures in 38,851 individuals 2019 In: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 51:11, s. 1624- Journal article (peer-reviewed)abstract Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank. We show that variability in subcortical volumes is heritable, and identify 48 significantly associated loci (40 novel at the time of analysis). Annotation of these loci by utilizing gene expression, methylation and neuropathological data identified 199 genes putatively implicated in neurodevelopment, synaptic signaling, axonal transport, apoptosis, inflammation/infection and susceptibility to neurological disorders. This set of genes is significantly enriched for Drosophila orthologs associated with neurodevelopmental phenotypes, suggesting evolutionarily conserved mechanisms. Our findings uncover novel biology and potential drug targets underlying brain development and disease.
8.	Davies, G., et al. (author) Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function 2018 In: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 9:1 Journal article (peer-reviewed)abstract General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16-102) and find 148 genome-wide significant independent loci (P < 5 × 10-8) associated with general cognitive function. Within the novel genetic loci are variants associated with neurodegenerative and neurodevelopmental disorders, physical and psychiatric illnesses, and brain structure. Gene-based analyses find 709 genes associated with general cognitive function. Expression levels across the cortex are associated with general cognitive function. Using polygenic scores, up to 4.3% of variance in general cognitive function is predicted in independent samples. We detect significant genetic overlap between general cognitive function, reaction time, and many health variables including eyesight, hypertension, and longevity. In conclusion we identify novel genetic loci and pathways contributing to the heritability of general cognitive function.
9.	Duncan, L, et al. (author) Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa 2017 In: The American journal of psychiatry. - : American Psychiatric Association Publishing. - 1535-7228 .- 0002-953X. ; 174:9, s. 850-858 Journal article (peer-reviewed)
10.	Yao, SY, et al. (author) Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches 2019 In: Biological psychiatry. - : Elsevier BV. - 1873-2402 .- 0006-3223. ; 86:8, s. 577-586 Journal article (peer-reviewed)

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Result 1-10 of 198

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Type of publication: journal article (168); conference paper (26); book chapter (2); book (1); other publication (1)

Type of content: peer-reviewed (156); other academic/artistic (41); pop. science, debate, etc. (1)

Author/Editor: Andreassen, OA (28); Steen, J (26); Melle, I (23); Djurovic, S (22); Malmstrom, V (21); KLARESKOG, L (20); show more...; Agartz, I (19); Steen, L (18); Steen, NE (17); Espeseth, T (16); Le Hellard, S (16); Steen, B (15); Amara, K (15); Palotie, A (14); Jonsson, EG (13); Israelsson, L (13); Gronwall, C. (11); Rujescu, D (11); Steen, VM (11); Westlye, LT (10); Corvin, A (10); Cichon, S (10); Donohoe, G (10); Westlye, Lars T (9); Widen, E (9); Athanasiu, L (8); Breen, G (8); Agartz, Ingrid (8); Andreassen, Ole A (8); Steen, Stig (8); Ames, D (8); Brodaty, H (8); Dale, AM (8); Thalamuthu, A (8); Wallentin, Lars (8); Djurovic, Srdjan (8); Nyberg, Lars, 1966- (8); Hjell, G (8); Lunding, SH (7); van der Meer, D (7); Andersson, Micael (7); Ehrlich, S (7); Giddaluru, S (7); Heinz, A (7); Schumann, G (7); Franke, B (7); Husted, Steen (7); van der Meer, Dennis (7); Alvarsson, M (7); Lager, I (7); show less...

University: Karolinska Institutet (112); Uppsala University (37); Lund University (30); University of Gothenburg (23); Umeå University (19); Örebro University (12); show more...; Stockholm University (9); Jönköping University (8); Linköping University (5); Royal Institute of Technology (4); Linnaeus University (4); Luleå University of Technology (3); Chalmers University of Technology (3); University of Borås (3); Swedish National Defence College (3); Kristianstad University College (2); Mid Sweden University (1); Högskolan Dalarna (1); show less...

Language: English (192); Swedish (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (82); Natural sciences (13); Social Sciences (11); Humanities (1)

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