| 1. |
- Ren, Mengying, et al.
(author)
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Concentration-Response Relationship between PM2.5 and Daily Respiratory Deaths in China : A Systematic Review and Metaregression Analysis of Time-Series Studies
- 2017
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In: BioMed Research International. - : Hindawi Publishing Corporation. - 2314-6133 .- 2314-6141.
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Research review (peer-reviewed)abstract
- The association between the particulate matters with aerodynamic diameter <= 2.5.mu m (PM2.5) and daily respiratory deaths, particularly the concentration-response pattern, has not been fully examined and established in China. We conducted a systematic review of time-series studies to compile information on the associations between PM2.5 concentration and respiratory deaths and used metaregression to assess the concentration-response relationship. Out of 1,957 studies screened, eleven articles in English and two articles in Chinese met the eligibility criteria. For single-day lags, per 10 mu g/m(3) increase in PM2.5 concentration was associated with 0.30 [95% confidence interval (CI): 0.10, 0.50] percent increase in daily respiratory deaths; for multiday lags, the corresponding increase in respiratory deaths was 0.69 (95% CI: 0.55, 0.83) percent. Difference in the effects was observed between the northern cities and the south cities in China. No statistically significant concentration-response relationship between PM2.5 concentrations and their effects was found. With increasingly wider location coverage for PM2.5 data, it is crucial to further investigate the concentration-response pattern of PM2.5 effects on respiratory and other cause-specific mortality for the refinement and adaptation of global and national air quality guidelines and targets.
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| 2. |
- Fang, Sisai, et al.
(author)
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Rate-based cell range expansion for mmWave massive MIMO enabled two-tier HetNets
- 2018
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In: 2018 24th Asia-Pacific Conference on Communications, APCC 2018. ; , s. 275-279
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Conference paper (peer-reviewed)abstract
- This paper presents a Rate-based Cell Range Expansion (CRE) for mmWave massive Multiple Input Multiple Output (MIMO) enabled two-tier heterogeneous networks (Het-Nets) where macro base stations (BSs) operate at sub-6 GHz and small BSs operate at mmWave band. We design a new user association scheme with the consideration of disparities between macro BSs and small BSs, chiefly bandwidths combined with Signal to Interference plus Noise Ratio (SINR), although conventional CRE provides a fixed Cell Selection Offset (CSO) for all user equipments (UEs). A downlink model is put forth to analyze the performance of the proposed Rate-based CRE. Our scheme consists of two parts: CRE between small cells and CRE between macro cells and small cells. We also investigate the proposed method by evaluating the average user throughput and cell edge user throughput. System-level computer simulation results such as average user throughput and 5-percentile user throughput are provided. The results confirm that the proposed method can improve the average user throughput compared with the conventional CRE scheme and maintain the cell edge user throughput for such multi-frequency cooperative networks. Thus, this scheme is an effective solution for user association in 5G mmWave HetNets.
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| 3. |
- Han, Mengying, et al.
(author)
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ChemHub: a knowledgebase of functional chemicals for synthetic biology studies
- 2021
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In: Bioinformatics. - : Oxford University Press (OUP). - 1367-4803 .- 1367-4811 .- 1460-2059. ; 37:22, s. 4275-4276
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Journal article (peer-reviewed)abstract
- The field of synthetic biology lacks a comprehensive knowledgebase for selecting synthetic target molecules according to their functions, economic applications and known biosynthetic pathways. We implemented ChemHub, a knowledgebase containing >90 000 chemicals and their functions, along with related biosynthesis information for these chemicals that was manually extracted from >600 000 published studies by more than 100 people over the past 10 years.
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| 4. |
- Zhang, Dachuan, et al.
(author)
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FRCD: A comprehensive food risk component database with molecular scaffold, chemical diversity, toxicity, and biodegradability analysis
- 2020
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In: Food Chemistry. - : Elsevier BV. - 0308-8146 .- 1873-7072. ; 318
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Journal article (peer-reviewed)abstract
- The presence of natural toxins, pesticide residues, and illegal additives in food products has been associated with a range of potential health hazards. However, no systematic database exists that comprehensively includes and integrates all research information on these compounds, and valuable information remains scattered across numerous databases and extensive literature reports. Thus, using natural language processing technology, we curated 12,018 food risk components from 152,737 literature reports, 12 authoritative databases, and numerous related regulatory documents. Data on molecular structures, physicochemical properties, chemical taxonomy, absorption, distribution, metabolism, excretion, toxicity properties, and physiological targets within the human body were integrated to afford the comprehensive food risk component database (FRCD, http://www.rxnfinder.org/frcd/). We also analyzed the molecular scaffold and chemical diversity, in addition to evaluating the toxicity and biodegradability of the food risk components. The FRCD could be considered a highly promising tool for future food safety studies.
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