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  • Savitski, Mikhail M., et al. (author)
  • Backbone carbonyl group basicities are related to gas-phase fragmentation of peptides and protein folding
  • 2007
  • In: Angewandte Chemie International Edition. - : Wiley. - 1433-7851 .- 1521-3773. ; 46:9, s. 1481-1484
  • Journal article (peer-reviewed)abstract
    • A strong correlation is found between the propensity of individual amino acids to induce peptide-bond cleavage in the gas phase (PAA-XX) and their structure-forming propensity (PS, red) and H-bond-accepting propensity (PH, blue). Thus, the same fundamental parameter, carbonyl group basicity, governs the formation of secondary protein structures in solution and directs fragmentation in the gas phase. (Graph Presented).
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Zubarev, Roman A (1)
Kjeldsen, Frank (1)
Savitski, Mikhail M (1)
Nielsen, Michael L (1)
Garbuzynskiy, Sergiy ... (1)
Galzitskaya, Oxana V ... (1)
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Surin, Alexey K. (1)
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University
Uppsala University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2007 (1)

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