1. |
- Hober, Sophia, Professor, 1965-, et al.
(author)
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Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay
- 2021
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In: Clinical & Translational Immunology. - : Wiley. - 2050-0068. ; 10:7
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Journal article (peer-reviewed)abstract
- Objective. The COVID-19 pandemic poses an immense need for accurate, sensitive and high-throughput clinical tests, and serological assays are needed for both overarching epidemiological studies and evaluating vaccines. Here, we present the development and validation of a high-throughput multiplex bead-based serological assay. Methods. More than 100 representations of SARS-CoV-2 proteins were included for initial evaluation, including antigens produced in bacterial and mammalian hosts as well as synthetic peptides. The five best-performing antigens, three representing the spike glycoprotein and two representing the nucleocapsid protein, were further evaluated for detection of IgG antibodies in samples from 331 COVID-19 patients and convalescents, and in 2090 negative controls sampled before 2020. Results. Three antigens were finally selected, represented by a soluble trimeric form and the S1-domain of the spike glycoprotein as well as by the C-terminal domain of the nucleocapsid. The sensitivity for these three antigens individually was found to be 99.7%, 99.1% and 99.7%, and the specificity was found to be 98.1%, 98.7% and 95.7%. The best assay performance was although achieved when utilising two antigens in combination, enabling a sensitivity of up to 99.7% combined with a specificity of 100%. Requiring any two of the three antigens resulted in a sensitivity of 99.7% and a specificity of 99.4%. Conclusion. These observations demonstrate that a serological test based on a combination of several SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.
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2. |
- Melke, Anna, et al.
(author)
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Vår offentliga förvaltning : Samverkan i välfärdspolitiken
- 2024. - 3
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Book (pop. science, debate, etc.)abstract
- Politik och förvaltning är två sidor av demokratin. Den politiska makten används för att styra samhällsutvecklingen utifrån ett ideologiskt synsätt, medan den offentliga förvaltningens uppgift är att tjäna andra, ytterst medborgarna. I detta ligger en unik utmaning: å ena sidan ska folket genom sina valda representanter styra och kontrollera förvaltningen, å andra sidan ska myndigheter och tjänstemän vara självständiga nog att hävda saklighet, opartiskhet och ett etiskt förhållningssätt. Denna bok ger en bild av dessa utmaningar. Den ger också en överblick som gör det lättare att navigera bland alla aktörer. Att hitta rätt bland internationella, statliga, regionala och lokala nivåer är nämligen inte självklart. Detta är en karta som dessutom blivit alltmer splittrad i takt med decentralisering, specialisering och privatisering. I den tredje upplagan av VÅR OFFENTLIGA FÖRVALTNING har lagar och förordningar inom välfärdssektorn uppdaterats, liksom andra viktiga förändringar inom offentlig förvaltning. Även den ökade digitaliseringen och betydelsen av medlemskapet i Nato behandlas. Boken vänder sig till högskolestuderande vid utbildningar i offentlig förvaltning, men också till den som redan arbetar inom sådana verksamheter. Det inkluderar så skilda yrken som kommunikatör, utredare, socionom, arbetsvetare, lärare, arbetsförmedlare, sjukvårdspersonal, polis och miljöinspektör. Boken vänder sig också till förtroendevalda politiker och andra som är intresserade av området. Anna Melke är journalist, fil. dr i offentlig förvaltning och verksam som forskare vid Göteborgsregionen, FoU i Väst. Hon har även medverkat i tidigare upplagor, som initialt författades av Hans Bengtsson. I denna upplaga medverkar två nya författare: Petra Svensson och Sara Svensson, docenter i statsvetenskap och verksamma som lektorer vid Högskolan i Halmstad.
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3. |
- Batory, Agnes, et al.
(författare)
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Regulating Collaboration : The Legal Framework of Collaborative Governance in Ten European Countries
- 2020
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Ingår i: International Journal of Public Administration. - New York : Taylor & Francis. - 0190-0692 .- 1532-4265. ; 43:9, s. 780-789
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Tidskriftsartikel (refereegranskat)abstract
- Many scholars have considered when and why collaboration between government agencies and societal actors occurs. This article argues that a simple but largely overlooked answer to these questions is that a formal legal or administrative requirement to do so is in place. Therefore, the objective is to substantiate whether there are legal requirements to collaborate and in what type of source and context this obligation applies in ten European countries. The main finding is that collaboration is underpinned by an extensive range of legal requirements in Europe, although imposing these requirements is generally not the main objective. © 2019 The Author(s).
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4. |
- Batory, Agnes, et al.
(författare)
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The fuzzy concept of collaborative governance : A systematic review of the state of the art
- 2019
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Ingår i: Central European Journal of Public Policy. - Warsaw : Sciendo. - 1802-4866. ; 13:2, s. 28-39
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Tidskriftsartikel (refereegranskat)abstract
- This article contributes to the consolidation and synthesis of scholarship on collaborative governance by expanding our knowledge of how the term is used in the academic literature and policy documents in a range of European countries. It adds value to the existing reviews of the field by conducting a systematic literature review on a corpus of over 700 article abstracts and a traditional literature review identifying five key analytical dimensions. The article also provides an exploratory analysis of grey literature hitherto outside the purview of researchers and considers the linguistic and cultural connotations that alter the meaning of the term when translated into new contexts in ten EU/EFTA countries. Findings indicate heterogeneity and fuzziness in the way the concept is used. The article argues that explicit positions with respect to five main analytical dimensions and taking into account the national connotations that the term carries across political systems would inject more clarity into the academic discourse. This, in turn, will help policymakers to make informed use of the concept, especially in multi-national policy-making arenas. © 2019 Agnes Batory et al., published by Sciendo 2019.
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5. |
- Batory, Agnes, et al.
(författare)
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The Use and Abuse of Participatory Governance by Populist Governments
- 2019
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Ingår i: Policy and politics (Print). - Bristol : Policy Press. - 0305-5736 .- 1470-8442. ; 47:2, s. 227-244
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Tidskriftsartikel (refereegranskat)abstract
- Populists claim that they alone represent the voice of the people against a corrupt elite. We argue that populist governments augment this claim by appropriating and manipulating the language and methods of participatory governance. Advancing an analytical framework on content, process, effect, resource efficiency and communication dimensions, we illustrate these arguments with the National Consultations in Hungary in 2010–18. Our conclusion for the case study is that these exercises were deeply flawed for securing popular input into policy-making. The implication for scholarship is that participatory governance enthusiasts need to be more aware not just of the uses, but also the abuses, of public input, while scholars of populism should pay more attention to the actual policies and practices populist actors employ to gain or maintain power.
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6. |
- Demidov, Andrey, et al.
(författare)
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Local cross-border cooperation at the European Union's external border : The meaning of local in the European Neighbourhood Policy
- 2013
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Ingår i: Regions and Cohesion. - Brooklyn, NY : Berghahn Books. - 2152-906X .- 2152-9078. ; 3:2, s. 22-46
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Tidskriftsartikel (refereegranskat)abstract
- The article examines a key priority in European Union policy toward the east and south: the effort to turn the external border areas into secure, stable, and prospering regions via support for cross-border cooperation. This features highly in a range of policies brought together under the European Neighbourhood Policy and in the partnership with Russia. The main question asked by the article is if these policies live up to the goal of involving local actors. Based on a content analysis of pro- gram documents and a categorization of project partners by actor type, the article argues that the notion of “local” can be subject to various un- derstandings, but if we understand local versus regional along the lines of the European Nomenclature of Territorial Units for Statistics (NUTS) classification, the policy in practice is undoubtedly tilted toward regional rather than local cross-border cooperation. In addition, the article argues that the four objectives of the European Neighbourhood and Partnership Instrument-Cross Border Cooperation (ENPI-CBC) do not match what could realistically be achieved with the resources available. © 2019 Berghahn Books
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7. |
- Eschweiler, Jennifer, et al.
(författare)
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The Reciprocity Dimension of Solidarity : Insights from Three European Countries
- 2019
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Ingår i: VOLUNTAS - International Journal of Voluntary and Nonprofit Organizations. - New York, NY : Springer. - 0957-8765 .- 1573-7888. ; 30:3, s. 549-561
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Tidskriftsartikel (refereegranskat)abstract
- The article argues that closer attention to how solidarity is understood and expressed in different European contexts can shed light on the conditions for establishing a social and solidarity economy. Drawing on data collected within the H2020 SOLIDUS project, which explores current expressions of European solidarity, the comparative analysis covers three social economy initiatives, each representing a country with different political and economic context. The analysis focuses on solidarity as reciprocity and, in particular, how it is affected by such factors as actor motivations, internal participatory functioning, resource mix and political legitimacy. While further empirical work is needed, the findings suggest that solidarity as reciprocity produced by social and solidarity economy organisations thrives where political institutions are both supportive and trusted, where public funding is accessible, and where partnerships with relatively autonomous social and solidarity economy organisations are genuinely collaborative. © 2019, The Author(s).
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8. |
- Irion, Kristina, et al.
(författare)
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The independence of media regulatory authorities in Europe
- 2019
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This IRIS Special focuses on the independence of regulatory authorities and bodies in the broadcasting and audiovisual media sector in Europe. These entities have proliferated according to the different legal traditions of the respective countries they belong to. They do not, therefore, conform one, single model. Nonetheless, they reflect a common approach of sorts with regard to the institutional set-up of regulatory governance. The independence of these entities is particularly important because it contributes to the broader objective of media independence, which is in itself an essential component of democracy.The creation, status and functioning of these regulatory authorities and bodies were shaped pursuant to the constitutional requirements and/or administrative practices of the countries that established them. As a result, each has distinct characteristics and levels of independence that differ according to where they are located. But when is an authority to be considered independent? The measurement of an entity's independence requires careful analysis of the legal texts setting it up, but also of the practices that are rooted in reality and reflect the sensitivities of the societies in question.This IRIS Special aims to enlighten the reader on the definition of the independence of a regulatory authority or body, on the criteria used to assess its independence, and on the legal framework embodying this independence at the European level, as well as provide analysis of the status and functioning of regulatory authorities and bodies in a selection of nine European countries: Bosnia and Herzegovina, Spain, Hungary, Ireland, Italy, the Netherlands, Poland, Sweden, and Slovenia. This sample reflects the different levels of independence that can be found across Europe. © European Audiovisual Observatory (Council of Europe), Strasbourg, September 2019
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9. |
- Karlsson, Peter, 1970-, et al.
(författare)
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Training high school students in resisting disinformation and conspiracy theories – Preliminary findings and experiences from an ongoing research project
- 2023
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Ingår i: 2023: Book of abstracts.
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Konferensbidrag (refereegranskat)abstract
- This paper draws on findings from an ongoing research project called ”Effects of a multi-module intervention designed to increase critical thinking and the ability to identify misinformation, disinformation, and conspiracy theories in high school students”. The aim of this project is to empirically evaluate an educational intervention consisting of six one-hour sessions. The sessions include traditional lectures regarding critical thinking, misinformation, disinformation, and conspiracy theories but also includes a game (Bad news), and group discussions, all designed to train high school students in critical thinking as well as the capacity to identify disinformation and conspiracy theories. The project combines competences from media and communication studies, psychology, political science, and data communication, and the intervention has so far been implemented in three Swedish high schools. In the paper we discuss preliminary findings and experiences drawn from the first phase of the project. We will also discuss the applicability of the intervention, and challenges that we have identified. © Author/s
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10. |
- Medve-Bálint, Gergő, et al.
(författare)
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Diversity and Development : Policy Entrepreneurship of Euroregional Initiatives in Central and Eastern Europe
- 2013
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Ingår i: Journal of Borderlands Studies. - New York, NY : Routledge. - 0886-5655 .- 2159-1229. ; 28:1, s. 15-31
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Tidskriftsartikel (refereegranskat)abstract
- The article builds on the authors' research into the formation of Euroregions in Central and Eastern Europe, addressing questions that may also be relevant on a broader European scale. Based on our empirical findings, in previous research we demonstrated why some local governments join Euroregions while others abstain. This article takes a further step and aims to discuss what happens once local governments become involved in them. How do motivations and expectations of local governments, as well as the power asymmetries between them, determine the capacity of these small-scale local cross-border collaborative initiatives to act as policy entrepreneurs? We take the three different Euroregional initiatives present in the Komárom–Esztergom region at the Hungarian–Slovakian border as illustrative examples. The empirical data were collected through personal interviews with the representatives of the Euroregions and with the highest political representatives of all local governments that are members on the Hungarian side. We find that differences in membership structure and in the motivational background influence their capacity to act as policy entrepreneurs operationalized as organizational development, diversification of resource base and appropriation of cross-border cooperation activities. We thus rely on a modified version of Markus Perkmann's theoretical framework built around the concept of policy entrepreneurship, but apply it to cases where we are able to control for variations in underlying macro-level conditions, such as politico-administrative or ethno-linguistic settings. The paper, therefore, highlights the differences in the internal dynamics of these initiatives and also challenges the perception of Euroregions as homogeneous institutions. © 2013 Copyright Association for Borderlands Studies.
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