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| 2. |
- Klasson, Stina, et al.
(author)
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Blood flow dynamics and sensitivity in breasts after reconstruction with DIEP-flap
- 2014
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In: Journal of Plastic Surgery and Hand Surgery. - 2000-656X. ; 48:6, s. 407-411
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Journal article (peer-reviewed)abstract
- A method of breast reconstruction is based on the Deep Inferior Epigastric Perforator (DIEP) technique. Skin and fat are transplanted from the abdomen to the chest; blood vessels are reconnected through microsurgery. Nerves are, however, left unconnected. This study aims to evaluate the blood flow and reinnervation of blood vessels and skin in breasts reconstructed by DIEP flaps without neural repair. In all, DIEP flaps of 10 patients were tested at an average of 16.3 months postoperatively. Blood flow was assessed by PeriScan PIM II System, both before and after indirect heating. Tactile perception threshold was assessed by Semmes-Weinstein monofilament and thermal sensibility by SENSELab MSA Thermotest. The patients' contralateral breasts were used as controls. The blood flow of the flaps was statistically significantly lower than in the control breasts, both before and after indirect heating. The change in blood flow after indirect heating did, however, not significantly differ when comparing the breasts. All flaps regained deep pressure sensibility in all four quadrants. Five patients regained even better sensibility in one of their quadrants. Seven patients regained perception of cold stimuli, five perceived warmth. This study has shown that skin blood flow regulation is present in DIEP flaps 1 year after reconstruction. Blood flow dynamics are very similar to those in the normal breast. There is also a recovery of tactile and thermal sensibility, but this study has not shown any clear parallels between recovery blood flow, tactile sensibility and thermal sensibility.
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| 3. |
- Svensson, Lennart, et al.
(author)
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Investigating measures for transfer function generation for visualization of MET biomedical data
- 2011
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In: WSCG '2011. - Plzen, Czech Republic : Union Agency. - 9788086943824 ; , s. 113-120
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Conference paper (peer-reviewed)abstract
- In this paper, the question of automatically setting transfer functions for volume images is further explored. Morespecifically, the focus is automatic visualization of Molecular Electron Tomography (MET) volume images usingone-dimensional transfer functions. We investigate how well a few general measures based on density, gradient,curvature and connected component information are suited for generating these transfer functions. To assessthis, an expert has set suitable transfer function levels manually and we have studied how these levels relate todifferent characteristics of the selected measures for 29 data sets. We have found that the measures can be used toautomatically generate a transfer function used to visualize MET data, to give the user an approximate view of thecomponents in the image.
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| 4. |
- Svensson, Lennart, et al.
(author)
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ProViz : a tool for explorative 3-D visualization and template matching in electron tomograms
- 2017
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In: Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization. - : Taylor & Francis. - 2168-1163 .- 2168-1171. ; 5:6, s. 446-454
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Journal article (peer-reviewed)abstract
- Visual understanding is a key aspect when studying electron tomography data-sets, aside quantitative assessments such as registration of high-resolution structures. We here present the free software tool ProViz (Protein Visualization) for visualisation and template matching in electron tomograms of biological samples. The ProViz software contains methods and tools which we have developed, adapted and computationally optimised for easy and intuitive visualisation and analysis of electron tomograms with low signal-to-noise ratio. ProViz complements existing software in the application field and serves as an easy and convenient tool for a first assessment and screening of the tomograms. It provides enhancements in three areas: (1) improved visualisation that makes connections as well as intensity differences between and within objects or structures easier to see and interpret, (2) interactive transfer function editing with direct visual result feedback using both piecewise linear functions and Gaussian function elements, (3) computationally optimised template matching and tools to visually assess and interactively explore the correlation results. The visualisation capabilities and features of ProViz are demonstrated on various biological volume data-sets: bacterial filament structures in vitro, a desmosome and the transmembrane cadherin connections therein in situ, and liposomes filled with doxorubicin in solution. The explorative template matching is demonstrated on a synthetic IgG data-set.
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| 5. |
- Svensson, Lennart, et al.
(author)
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Towards automatic visualization of MET biomedical data
- 2010
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In: Rapport / Centrum för bildanalys. - Uppsala : Uppsala University Printers. - 1100-6641. ; , s. 83-86, s. 83-86
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Conference paper (other academic/artistic)abstract
- This work describes a starting point for estimationof parameters when visualizing Molecular ElectronTomography (MET) volumes. The aim is to instantly and automatically produce an initial rendering of the biological molecules in a MET volume. A one-dimensional transfer function with fixed primitives is suggested to highlight the structure and interaction of the molecules. The correlation between manually set parameters by an expert user for these primitives and measures related to topology, gradient and curvature are explored. The work is part of the ProViz project aiming at creating better tools for analysis and hapto-visualization of MET volumes of proteins
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| 6. |
- Arcelli, Carlo, et al.
(author)
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Computing and analysing convex deficiencies to characterise 3D complex objects
- 2005
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In: Image and Vision Computing: Discrete Geometry for Computer Imagery. ; 23:2, s. 203-211
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Journal article (peer-reviewed)abstract
- Entities such as object components, cavities, tunnels and concavities in 3D digital images can be useful in the framework of object analysis. For each object component, we first identify its convex deficiencies, by subtracting the object component from a covering polyhedron approximating the convex hull. Watershed segmentation is then used to decompose complex convex deficiencies into simpler parts, corresponding to individual cavities, concavities and tunnels of the object component. These entities are finally described by means of a representation system accounting for the shape features characterising them.
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| 7. |
- Aronsson, Mattias, et al.
(author)
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Curvature Measurements for fibres in 3D Images of Paper
- 2002
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In: Proceedings SSAB'02 Symposium on Image Analysis. ; , s. 165-168
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Conference paper (other academic/artistic)abstract
- When analysing fibres in paper using computerised image analysis applied to 3D i mages of paper, one measure of interest is the curvature along each individual fibre and how the curvature changes due to interaction with adjacent fibres. Starting from a cu
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| 8. |
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| 9. |
- Axelsson, Maria, et al.
(author)
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3D pore structure characterisation of paper
- 2010
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In: Pattern Analysis and Applications. - : Springer Science and Business Media LLC. - 1433-7541 .- 1433-755X. ; 13:2, s. 159-172
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Journal article (peer-reviewed)abstract
- Pore structure characterisation of paper, using automated image analysis methods, has previously been performed in two-dimensional images. Three dimensional (3D) images have become available and thereby new representations and corresponding measurements are needed for 3D pore structure characterisation. In this article, we present a new pore structure representation, the individual pore-based skeleton, and new quantitative measurements for individual pores in 3D, such as surface area, orientation, anisotropy, and size distributions. We also present measurements for network relations, like tortuosity and connectivity. The data used to illustrate the pore structure representations and corresponding measurements are high resolution X-ray microtomography volume images of a layered duplex board imaged at the European Synchrotron Radiation Facility (ESRF). Quantification of the pore structure is exemplified and the results show that differences in pore structure between the layers in the cardboard can be characterised using the presented methods.
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