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  • Result 1-4 of 4
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1.
  • Kattge, Jens, et al. (author)
  • TRY plant trait database - enhanced coverage and open access
  • 2020
  • In: Global Change Biology. - : Wiley-Blackwell. - 1354-1013 .- 1365-2486. ; 26:1, s. 119-188
  • Journal article (peer-reviewed)abstract
    • Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.
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3.
  • Chng, Kern Rei, et al. (author)
  • Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment
  • 2020
  • In: Nature Medicine. - : Springer Science and Business Media LLC. - 1078-8956 .- 1546-170X. ; 26, s. 941-951
  • Journal article (peer-reviewed)abstract
    • Although disinfection is key to infection control, the colonization patterns and resistomes of hospital-environment microbes remain underexplored. We report the first extensive genomic characterization of microbiomes, pathogens and antibiotic resistance cassettes in a tertiary-care hospital, from repeated sampling (up to 1.5 years apart) of 179 sites associated with 45 beds. Deep shotgun metagenomics unveiled distinct ecological niches of microbes and antibiotic resistance genes characterized by biofilm-forming and human-microbiome-influenced environments with corresponding patterns of spatiotemporal divergence. Quasi-metagenomics with nanopore sequencing provided thousands of high-contiguity genomes, phage and plasmid sequences (>60% novel), enabling characterization of resistome and mobilome diversity and dynamic architectures in hospital environments. Phylogenetics identified multidrug-resistant strains as being widely distributed and stably colonizing across sites. Comparisons with clinical isolates indicated that such microbes can persist in hospitals for extended periods (>8 years), to opportunistically infect patients. These findings highlight the importance of characterizing antibiotic resistance reservoirs in hospitals and establish the feasibility of systematic surveys to target resources for preventing infections. Spatiotemporal characterization of microbial diversity and antibiotic resistance in a tertiary-care hospital reveals broad distribution and persistence of antibiotic-resistant organisms that could cause opportunistic infections in a healthcare setting.
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4.
  • Popp, David, et al. (author)
  • Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser
  • 2017
  • In: CYTOSKELETON. - : WILEY. - 1949-3584 .- 1949-3592. ; 74:12, s. 472-481
  • Journal article (peer-reviewed)abstract
    • A major goal for X-ray free-electron laser (XFEL) based science is to elucidate structures of biological molecules without the need for crystals. Filament systems may provide some of the first single macromolecular structures elucidated by XFEL radiation, since they contain one-dimensional translational symmetry and thereby occupy the diffraction intensity region between the extremes of crystals and single molecules. Here, we demonstrate flow alignment of as few as 100 filaments (Escherichia coli pili, F-actin, and amyloid fibrils), which when intersected by femtosecond X-ray pulses result in diffraction patterns similar to those obtained from classical fiber diffraction studies. We also determine that F-actin can be flow-aligned to a disorientation of approximately 5 degrees. Using this XFEL-based technique, we determine that gelsolin amyloids are comprised of stacked -strands running perpendicular to the filament axis, and that a range of order from fibrillar to crystalline is discernable for individual -synuclein amyloids.
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  • Result 1-4 of 4
Type of publication
journal article (3)
editorial collection (1)
Type of content
peer-reviewed (3)
other academic/artistic (1)
Author/Editor
Thomas, Elisabeth (1)
Franceschini, Amy (1)
Swaine, Michael (1)
Diaz, Sandra (1)
Ostonen, Ivika (1)
Tedersoo, Leho (1)
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Ding, Ke (1)
Bond-Lamberty, Ben (1)
Moretti, Marco (1)
Wang, Feng (1)
Verheyen, Kris (1)
Graae, Bente Jessen (1)
Afshinnekoo, Ebrahim (1)
Bhattacharya, Chandr ... (1)
Castro-Nallar, Eduar ... (1)
Deng, Youping (1)
Desnues, Christelle (1)
Dias-Neto, Emmanuel (1)
Elhaik, Eran (1)
Iraola, Gregorio (1)
Jang, Soojin (1)
Łabaj, Paweł P. (1)
Mason, Christopher E ... (1)
Nagarajan, Niranjan (1)
Suzuki, Haruo (1)
Bhattacharyya, Malay (1)
Robinson, Robert C. (1)
Isaac, Marney (1)
Lewis, Simon L. (1)
Zieminska, Kasia (1)
Phillips, Oliver L. (1)
Jackson, Robert B. (1)
Reichstein, Markus (1)
Hickler, Thomas (1)
Rogers, Alistair (1)
Udekwu, Klas (1)
Manzoni, Stefano (1)
Seuring, Carolin (1)
Pakeman, Robin J. (1)
Poschlod, Peter (1)
Dainese, Matteo (1)
Ruiz-Peinado, Ricard ... (1)
van Bodegom, Peter M ... (1)
Sauter, Nicholas K. (1)
Brewster, Aaron S. (1)
Wellstein, Camilla (1)
Gross, Nicolas (1)
Violle, Cyrille (1)
Björkman, Anne, 1981 (1)
Rillig, Matthias C. (1)
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University
University of Gothenburg (2)
Stockholm University (2)
Umeå University (1)
Uppsala University (1)
Karlstad University (1)
Swedish University of Agricultural Sciences (1)
Language
English (4)
Research subject (UKÄ/SCB)
Natural sciences (3)
Medical and Health Sciences (1)
Humanities (1)

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