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- Asim, Zeeshan, et al.
(author)
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Significance of Sustainable Packaging: A Case-Study from a Supply Chain Perspective
- 2022
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In: Applied System Innovation. - : MDPI AG. - 2571-5577. ; 5:6
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Journal article (peer-reviewed)abstract
- The present case study-based research provides insights of the current packaging practices with a supply chain perspective and proposed sustainable packaging options that would cut down the environmental impact from supply chain operations at Midas Safety. The case study is based on qualitative research that used semi-structured open-ended interviews and observations to understand the current processes of the packaging and supply chain department of Midas Safety and how they are planning to adapt sustainability to their processes. Considering the current packaging practices, the study aimed to develop improved sustainable packaging practices with a supply chain aspect in order to cut down the negative environmental aspect such as standardization in packaging for all customers, elimination of wood pallets, developing local suppliers, change in packaging design, making the packaging more compact and lightweight, reducing carbon footprint and fuel consumption by encouraging trade through sea instead of air. The results concluded that internal factors such as alternate packaging material (like Mondi’s Aegispaper, Arjowiggins’ and Corrugated Bubble Wrap) along with the suggested sustainable packaging practices discussed above and external factors such as availability of local vendors are important requirements for successful sustainable packaging development.
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| 2. |
- Ellencrona, Karin, et al.
(author)
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Flavivirus NS5 associates with host-cell proteins zonula occludens-1 (ZO-1) and regulating synaptic membrane exocytosis-2 (RIMS2) via an internal PDZ binding mechanism
- 2009
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In: Biological chemistry (Print). - Berlin : Walter de Gruyter. - 1431-6730 .- 1437-4315. ; 390:4, s. 319-323
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Journal article (peer-reviewed)abstract
- Dengue virus (DENV) and tick-borne encephalitis virus (TBEV) are flaviviruses, which can cause lethal hemorrhagic fever and encephalitis, respectively. Here, we demonstrate that the TBEV-NS5 and DENV-NS5 proteins use an internal binding mechanism to target human PDZ proteins. TBEV-NS5 has high affinity to regulating synaptic membrane exocytosis-2 (RIMS2) and Scribble, whereas DENV-NS5 binds primarily to the tight junction protein zonula occludens-1 (ZO-1). Targeting of TBEV-NS5 to the plasma membrane is stabilised by ZO-1; however, DENV-NS5 co-localises with ZO-1 in the nucleus. These interactions have potential important roles in the ability of flaviviruses to manipulate cell proliferation, junction permeability and the interferon pathways.
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