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- Saari, Ulla A., et al.
(author)
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Exploring factors influencing the acceptance of social robots among early adopters and mass market representatives
- 2022
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In: Robotics and Autonomous Systems. - : Elsevier. - 0921-8890 .- 1872-793X. ; 151
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Journal article (peer-reviewed)abstract
- When designing social robots, it is crucial to understand the diverse expectations of different kinds of innovation adopters. Different factors influence early adopters of innovations and mass market representatives’ perceptions of the usefulness of social robots. The first aim of the study was to test how applicable the technology acceptance model 3 (TAM3) is in the context of social robots. Participants’ acceptance of social robotics in a workplace environment in the fuzzy front-end (FFE) innovation phase of a robot development project was examined. Based on the findings for the model, we developed a reduced version of the TAM3 that is more applicable for social robots. The second objective was to analyze how early adopters’ and mass market representatives’ acceptance of social robots differs. Quantitative research methods were used. For early adopters, result demonstrability has a significant influence on perceived usefulness of social robots, while for mass market representatives, perceived enjoyment has a more significant influence on perceived usefulness. The findings indicate that users’ innovation adoption style influences the factors that users consider important in the usefulness of social robots. Robot developers should take these into account during the FFE innovation phase.
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- Loid, P, et al.
(author)
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Targeted Exome Sequencing of Genes Involved in Rare CNVs in Early-Onset Severe Obesity
- 2022
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In: Frontiers in genetics. - : Frontiers Media SA. - 1664-8021. ; 13, s. 839349-
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Journal article (peer-reviewed)abstract
- Context: Rare copy number variants (CNVs) have been associated with the development of severe obesity. However, the potential disease-causing contribution of individual genes within the region of CNVs is often not known.Objective: Screening of rare variants in genes involved in CNVs in Finnish patients with severe early-onset obesity to find candidate genes linked to severe obesity.Methods: Custom-made targeted exome sequencing panel to search for rare (minor allele frequency <0.1%) variants in genes affected by previously identified CNVs in 92 subjects (median age 14 years) with early-onset severe obesity (median body mass index (BMI) Z-score + 4.0).Results: We identified thirteen rare heterozygous variants of unknown significance in eleven subjects in twelve of the CNV genes. Two rare missense variants (p.Pro405Arg and p.Tyr232Cys) were found in SORCS1, a gene highly expressed in the brain and previously linked to diabetes risk. Four rare variants were in genes in the proximal 16p11.2 region (a frameshift variant in TAOK2 and missense variants in SEZ6L2, ALDOA and KIF22) and three rare missense variants were in genes in the 22q11.21 region (AIFM3, ARVCF and KLHL22).Conclusion: We report several rare variants in CNV genes in subjects with childhood obesity. However, the role of the individual genes in the previously identified rare CNVs to development of obesity remains uncertain. More studies are needed to understand the potential role of the specific genes within obesity associated CNVs.
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- Schneider, Thomas, et al.
(author)
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Evaluation and control of occupational health risks from nanoparticles
- 2007
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Reports (peer-reviewed)abstract
- Rapid growth in the nanoparticle industry is anticipated in the Nordic countries owing to highly focused national research and investment initiatives. Knowledge on consequences for occupational exposures to engineered nanoparticles and appropriate technical control levels is still limited. This report explores existing knowledge on exposure risks and technical control approaches. The report concludes that data are too limited to allow general conclusions to be drawn regarding risks of exposure to engineered nanoparticles.Engineering techniques for controlling nanoparticle exposure can build on the current knowledge and approaches to control exposure to e.g. welding fume and carbon black. There is a need for improving the quality of information provided in Material Safety Data Sheets.
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- Tossavainen, H, et al.
(author)
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NMR solution structure of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea
- 2003
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In: European Journal of Biochemistry. - : Wiley. - 0014-2956 .- 1432-1033. ; 270:11, s. 2505-2512
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Journal article (peer-reviewed)abstract
- The structure of calerythrin, a prokaryotic 20 kDa calcium-binding protein has been determined by solution NMR spectroscopy. Distance, dihedral angle, J coupling, secondary chemical shift, residual dipolar coupling and radius of gyration restraints reveal four EF-hand motifs arranged in a compact globular structure. A tight turn in the middle of the amino acid sequence brings the two halves, each comprising a pair of EF-hands, close together. The structural similarity between calerythrin and the eukaryotic sarcoplasmic calcium-binding proteins is notable.
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- Tossavainen, Timo, et al.
(author)
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Explorations of Finnish mathematics students' beliefs about the nature of mathematics
- 2017
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In: Far East Journal of Mathematical Education. - : Pushpa Publishing House. - 0973-5631. ; 17:3, s. 105-120
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Journal article (peer-reviewed)abstract
- According to certain surveys made in Germany, mathematics can be seen either as a stagnant structure (formalism-related orientation), a collection of rules, formulas and methods (scheme-related orientation), an active and creative construction process (process-related orientation), or as a method of describing the real world (application- related orientation). We examine how a twenty-item test of students’ orientations for students’ beliefs on the nature of mathematics, which was developed in the German context, translates to the Finnish culture remaining validity. Altogether 310 first-year students from three Finnish universities took part in the study. We apply confirmatory factor analysis to reveal that a slightly modified version the translated questionnaire is applicable also in the Finnish context. Using data collected with the translated questionnaire, we construct a binary regression models to predict students’ choosing between a technical and an ordinary university, and how probability that a student chooses teacher’s study programme slightly decreases if the static view grows stronger in his/her view of mathematics. Further, we see that all four orientations exist almost equally strong in the Finnish students’ beliefs.
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