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1.	Bojesen, SE, et al. (author) Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer 2013 In: Nature genetics. - New york : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:4, s. 371-384 Journal article (peer-reviewed)
2.	Glubb, DM, et al. (author) Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1 2015 In: American journal of human genetics. - : Elsevier BV. - 1537-6605 .- 0002-9297. ; 96:1, s. 5-20 Journal article (peer-reviewed)
3.	Michailidou, K, et al. (author) Large-scale genotyping identifies 41 new loci associated with breast cancer risk 2013 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:4, s. 353-361 Journal article (peer-reviewed)
4.	Reddy, A, et al. (author) FAVORABLE CLINICAL RESPONSE TO BELIMUMAB AT THREE MONTHS 2013 In: ANNALS OF THE RHEUMATIC DISEASES. - 0003-4967. ; 65, s. S668-S668 Conference paper (other academic/artistic)
5.	Shum, KM, et al. (author) Favorable Response to Belimumab At Three Months. 2012 In: ARTHRITIS AND RHEUMATISM. - 0004-3591. ; 64:10, s. S610-S610 Conference paper (other academic/artistic)
6.	Su, PJ, et al. (author) Circulating Tumour Cells as an Independent Prognostic Factor in Patients with Advanced Oesophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy 2016 In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 6, s. 31423- Journal article (peer-reviewed)abstract The role of circulating tumour cells (CTCs) in advanced oesophageal cancer (EC) patients undergoing concurrent chemoradiotherapy (CCRT) remains uncertain. A negative selection protocol plus flow cytometry was validated to efficiently identify CTCs. The CTC number was calculated and analysed for survival impact. The protocol’s efficacy in CTC identification was validated with a recovery rate of 44.6 ± 9.1% and a coefficient of variation of 20.4%. Fifty-seven patients and 20 healthy donors were enrolled. Initial staging, first response to CRT, and surgery after CRT were prognostic for overall survival, with P values of <0.0001, <0.0001, and <0.0001, respectively. The CTC number of EC patients is significantly higher (P = 0.04) than that of healthy donors. Multivariate analysis for disease-specific progression-free survival showed that surgery after response to CCRT, initial stage, and CTC number (≥21.0 cells/mL) played independent prognostic roles. For overall survival, surgery after CCRT, performance status, initial stage, and CTC number were significant independent prognostic factors. In conclusion, a negative selection plus flow cytometry protocol efficiently detected CTCs. The CTC number before CCRT was an independent prognostic factor in patients with unresectable oesophageal squamous cell carcinoma. Further large-scale prospective studies for validation are warranted.

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Type of publication: journal article (4); conference paper (2)

Type of content: peer-reviewed (4); other academic/artistic (2)

Author/Editor: Jones, M. (3); Miao, H. (3); Zheng, W. (3); Benitez, J. (3); Miller, N (3); Brenner, H (3); show more...; Kang, D. (3); Dennis, J (3); Wang, Q. (3); Ito, H. (3); Blomqvist, C (3); McKay, J (3); Cai, H. (3); Shu, XO (3); Gao, YT (3); Hall, P (3); Humphreys, K (3); Czene, K (3); Lindblom, A (3); Peterlongo, P (3); Anton-Culver, H (3); Giles, GG (3); Milne, RL (3); Signorello, LB (3); Michailidou, K (3); Pita, G (3); Bolla, MK (3); Margolin, S (3); Ashworth, A (3); Orr, N (3); Matsuo, K (3); Iwata, H (3); Hartman, M (3); Tomlinson, I (3); Noh, DY (3); Hopper, JL (3); Southey, MC (3); Teo, SH (3); Yip, CH (3); Brauch, H (3); Bruning, T (3); Hamann, U (3); Dunning, AM (3); Shah, M (3); Andrulis, IL (3); Knight, JA (3); Glendon, G (3); Schmidt, MK (3); Broeks, A (3); Fasching, PA (3); show less...

University: Karolinska Institutet (6); Umeå University (1); Lund University (1)

Language: English (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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