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- Chiotellis, Aristeidis, et al.
(författare)
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Novel chemoselective (18)F-radiolabeling of thiol-containing biomolecules under mild aqueous conditions
- 2016
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Ingår i: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; 52:36, s. 6083-6086
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Tidskriftsartikel (refereegranskat)abstract
- We report a novel prosthetic group based on a heterocyclic methylsulfone derivative for the rapid, stable, and chemoselective (18)F-labeling of thiol-containing (bio)molecules under mild aqueous reaction conditions. Compared to established maleimide approaches, the new methodology displays some clear advantages for imaging probe development.
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