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- Bosch, Jan, 1967, et al.
(author)
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Pivots and Architectural Decisions: Two Sides of the Same Medal?
- 2013
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In: Eighth International Conference on Software Engineering Advances, ICSEA 2013. October 27, 2013 to October 31, Venice, Italy. - 9781612083049 ; , s. 310-317
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Conference paper (peer-reviewed)abstract
- Software architecture research has gained maturity over the last decades. It focuses on architectural knowledge, documentation, the role of the architect and rationale for the architecture decisions made. It is widely recognized that considering architecture decisions as first class entities helps in designing and maintaining architectures. In the entrepreneurial and new product development space, the lean startup movement is gaining momentum as one of the most notable ways to develop products. During new product development in highly uncertain environments, speed is the most important factor. Speed to get on the market, speed to learn from your customers, but also speed to tackle technological risks. Because the runway for new product development is short, it is important to experiment and make decisions quickly. The pivot plays a crucial role as a business decision for new product development. Both pivots and architectural design decisions can be seen as highly influential aspects for a product. In our research, we investigate what the fields of architecture research and lean startup could learn from each other. We focus our research on the two most important aspects of these movements: the architecture decision and the pivot, and show that they can be seen as two sides of the same medal representing the technical and the business side of the product.
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| 2. |
- Arrhenius, Karine, et al.
(author)
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Suitability of vessels and adsorbents for the short-term storage of biogas/biomethane for the determination of impurities – Siloxanes, sulfur compounds, halogenated hydrocarbons, BTEX
- 2017
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In: Biomass and Bioenergy. - : Elsevier BV. - 0961-9534 .- 1873-2909. ; 105, s. 127-135
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Journal article (peer-reviewed)abstract
- Biogas is a renewable energy source with many different production pathways and various excellent opportunities to use, for example as vehicle fuel (biomethane). Reliable analytical methodologies for assessing the quality of the gas are critical to ensure that the gas can technically and safely be used. An essential part of any procedure aiming to determine the quality is the sampling and the transfer to the laboratory. One of the greatest challenges is then to ensure that the composition of the sample collected does not change between the time of sampling and the analysis. The choice of the sampling vessel to be used must be made only after fully assessing its short-term stability. In this paper, the results from short-term stability studies in different vessels (cylinders, bags and sorbents) are presented for siloxanes, BTEX, halogenated hydrocarbons and sulfur compounds. Storage of dry gas at high pressure (> 6 MPa) appears to be a good alternative however it is currently challenging to find an optimal treatment of the cylinders for all species to be assessed in biogas/biomethane. At lower pressure, adsorption effects on the inner surface of the cylinders have been observed. The use of bags and sorbent tubes also shows limitation. No existing sorbent tubes are sufficiently universal as to trap all possible impurities and high boiling compounds may adsorbed on the inner surface of the bags walls. Moreover, the presence of water when storing biogas most certainly impacts the storage stability of compounds in most vessels. Using at least two sampling methods for a given compound and comparing results will allow taking into account the eventual effects of water vapour, and adsorption on the inner surface of the vessels.
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| 3. |
- De Groot, Natasja M.S., et al.
(author)
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Critical appraisal of technologies to assess electrical activity during atrial fibrillation : a position paper from the European Heart Rhythm Association and European Society of Cardiology Working Group on eCardiology in collaboration with the Heart Rhythm Society, Asia Pacific Heart Rhythm Society, Latin American Heart Rhythm Society and Computing in Cardiology
- 2022
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In: Europace. - : Oxford University Press (OUP). - 1099-5129. ; 24:2, s. 313-330
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Research review (peer-reviewed)abstract
- We aim to provide a critical appraisal of basic concepts underlying signal recording and processing technologies applied for (i) atrial fibrillation (AF) mapping to unravel AF mechanisms and/or identifying target sites for AF therapy and (ii) AF detection, to optimize usage of technologies, stimulate research aimed at closing knowledge gaps, and developing ideal AF recording and processing technologies. Recording and processing techniques for assessment of electrical activity during AF essential for diagnosis and guiding ablative therapy including body surface electrocardiograms (ECG) and endo- or epicardial electrograms (EGM) are evaluated. Discussion of (i) differences in uni-, bi-, and multi-polar (omnipolar/Laplacian) recording modes, (ii) impact of recording technologies on EGM morphology, (iii) global or local mapping using various types of EGM involving signal processing techniques including isochronal-, voltage- fractionation-, dipole density-, and rotor mapping, enabling derivation of parameters like atrial rate, entropy, conduction velocity/direction, (iv) value of epicardial and optical mapping, (v) AF detection by cardiac implantable electronic devices containing various detection algorithms applicable to stored EGMs, (vi) contribution of machine learning (ML) to further improvement of signals processing technologies. Recording and processing of EGM (or ECG) are the cornerstones of (body surface) mapping of AF. Currently available AF recording and processing technologies are mainly restricted to specific applications or have technological limitations. Improvements in AF mapping by obtaining highest fidelity source signals (e.g. catheter-electrode combinations) for signal processing (e.g. filtering, digitization, and noise elimination) is of utmost importance. Novel acquisition instruments (multi-polar catheters combined with improved physical modelling and ML techniques) will enable enhanced and automated interpretation of EGM recordings in the near future.
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| 6. |
- Guido, Rodrigo Capobianco, et al.
(author)
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IEEE Signal Processing Society : Celebrating 75 Years of Remarkable Achievements [From the Guest Editors]
- 2023
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In: IEEE signal processing magazine (Print). - : Institute of Electrical and Electronics Engineers (IEEE). - 1053-5888 .- 1558-0792. ; 40:4, s. 3-6
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Journal article (peer-reviewed)abstract
- It is our great pleasure to introduce the first part of this special issue to you! The IEEE Signal Processing Society (SPS) has completed 75 years of remarkable service to the signal processing community. When the Society was founded in 1948, we couldn't imagine, for instance, how wireless networks of smartphones would be able to connect us easily at all times, or that an image processing algorithm would be able to detect cancer in a few seconds. Those are just simple examples of the immense technological progress over the past 75 years, which became possible thanks in great part to the dedicated work of professional members of the SPS.
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| 8. |
- Harmon, Matthew B.A., et al.
(author)
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Practice of mechanical ventilation in cardiac arrest patients and effects of targeted temperature management : A substudy of the targeted temperature management trial
- 2018
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In: Resuscitation. - : Elsevier BV. - 0300-9572. ; 129, s. 29-36
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Journal article (peer-reviewed)abstract
- Aims: Mechanical ventilation practices in patients with cardiac arrest are not well described. Also, the effect of temperature on mechanical ventilation settings is not known. The aims of this study were 1) to describe practice of mechanical ventilation and its relation with outcome 2) to determine effects of different target temperatures strategies (33 °C versus 36 °C) on mechanical ventilation settings. Methods: This is a substudy of the TTM-trial in which unconscious survivors of a cardiac arrest due to a cardiac cause were randomized to two TTM strategies, 33 °C (TTM33) and 36 °C (TTM36). Mechanical ventilation data were obtained at three time points: 1) before TTM; 2) at the end of TTM (before rewarming) and 3) after rewarming. Logistic regression was used to determine an association between mechanical ventilation variables and outcome. Repeated-measures mixed modelling was performed to determine the effect of TTM on ventilation settings. Results: Mechanical ventilation data was available for 567 of the 950 TTM patients. Of these, 81% was male with a mean (SD) age of 64 (12) years. At the end of TTM median tidal volume was 7.7 ml/kg predicted body weight (PBW)(6.4–8.7) and 60% of patients were ventilated with a tidal volume ≤ 8 ml/kg PBW. Median PEEP was 7.7cmH2O (6.4–8.7) and mean driving pressure was 14.6 cmH2O (±4.3). The median FiO2 fraction was 0.35 (0.30–0.45). Multivariate analysis showed an independent relationship between increased respiratory rate and 28-day mortality. TTM33 resulted in lower end-tidal CO2 (Pgroup = 0.0003) and higher alveolar dead space fraction (Pgroup = 0.003) compared to TTM36, while PCO2 levels and respiratory minute volume were similar between groups. Conclusions: In the majority of the cardiac arrest patients, protective ventilation settings are applied, including low tidal volumes and driving pressures. High respiratory rate was associated with mortality. TTM33 results in lower end-tidal CO2 levels and a higher alveolar dead space fraction compared to TTTM36.
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| 9. |
- Knief, Ulrich, et al.
(author)
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Highly pathogenic avian influenza causes mass mortality in Sandwich Tern Thalasseus sandvicensis breeding colonies across north-western Europe
- 2024
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In: Bird conservation international. - : Cambridge University Press. - 0959-2709 .- 1474-0001. ; 34
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Journal article (peer-reviewed)abstract
- In 2022, highly pathogenic avian influenza (HPAI) A(H5N1) virus clade 2.3.4.4b became enzootic and caused mass mortality in Sandwich TernThalasseus sandvicensis and other seabird species across north-western Europe. We present data on the characteristics of the spread of the virus between and within breeding colonies and the number of dead adult Sandwich Terns recorded at breeding sites throughout north-western Europe. Within two months of the first reported mortalities, 20,531 adult Sandwich Terns were found dead, which is >17% of the total north-western European breeding population. This is probably an under-representation of total mortality, as many carcasses are likely to have gone unnoticed and unreported. Within affected colonies, almost all chicks died. After the peak of the outbreak, in a colony established by late breeders, 25.7% of tested adults showed immunity to HPAI subtype H5. Removal of carcasses was associated with lower levels of mortality at affected colonies. More research on the sources and modes of transmission, incubation times, effective containment, and immunity is urgently needed to combat this major threat for colonial seabirds.
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