↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Vickers J) "

Search: WFRF:(Vickers J)

Result 1-10 of 121

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	2021 swepub:Mat__t
2.	2019 Journal article (peer-reviewed)
3.	Arndt, D. S., et al. (author) STATE OF THE CLIMATE IN 2017 2018 In: Bulletin of The American Meteorological Society - (BAMS). - : American Meteorological Society. - 0003-0007 .- 1520-0477. ; 99:8, s. S1-S310 Research review (peer-reviewed)
4.	Kotfis, K, et al. (author) A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit 2019 In: Journal of critical care. - : Elsevier BV. - 1557-8615 .- 0883-9441. ; 51, s. 122-132 Journal article (peer-reviewed)
5.	Halliday, A, et al. (author) Status update and interim results from the asymptomatic carotid surgery trial-2 (ACST-2) 2013 In: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. - : Elsevier BV. - 1532-2165. ; 46:5, s. 510-518 Journal article (peer-reviewed)
6.	Bancroft, EK, et al. (author) Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study 2014 In: European urology. - : Elsevier BV. - 1873-7560 .- 0302-2838. ; 66:3, s. 489-499 Journal article (peer-reviewed)
7.	Mikropoulos, C, et al. (author) Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition 2018 In: British journal of cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 118:6, s. e17- Journal article (peer-reviewed)
8.	Mikropoulos, C, et al. (author) Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition 2018 In: British journal of cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 118:2, s. 266-276 Journal article (peer-reviewed)
9.	Page, EC, et al. (author) Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers 2019 In: European urology. - : Elsevier BV. - 1873-7560 .- 0302-2838. ; 76:6, s. 831-842 Journal article (peer-reviewed)
10.	Sheikh, A., et al. (author) Enterotoxigenic Escherichia coli Degrades the Host MUC2 Mucin Barrier To Facilitate Critical Pathogen-Enterocyte Interactions in Human Small Intestine 2022 In: Infection and Immunity. - : American Society for Microbiology. - 0019-9567 .- 1098-5522. ; 90:2 Journal article (peer-reviewed)abstract Enterotoxigenic Escherichia coli (ETEC) isolates are genetically diverse pathological variants of E. coli defined by the production of heat-labile (LT) and/or heat-stable (ST) toxins. ETEC strains are estimated to cause hundreds of millions of cases of diarrheal illness annually. However, it is not clear that all strains are equally equipped to cause disease, and asymptomatic colonization with ETEC is common in low- to middle-income regions lacking basic sanitation and clean water where ETEC are ubiquitous. Recent molecular epidemiology studies have revealed a significant association between strains that produce EatA, a secreted autotransporter protein, and the development of symptomatic infection. Here, we demonstrate that LT stimulates production of MUC2 mucin by goblet cells in human small intestine, enhancing the protective barrier between pathogens and enterocytes. In contrast, using explants of human small intestine as well as small intestinal enteroids, we show that EatA counters this host defense by engaging and degrading the MUC2 mucin barrier to promote bacterial access to target enterocytes and ultimately toxin delivery, suggesting that EatA plays a crucial role in the molecular pathogenesis of ETEC. These findings may inform novel approaches to prevention of acute diarrheal illness as well as the sequelae associated with ETEC and other pathogens that rely on EatA and similar proteases for efficient interaction with their human hosts. © 2022 American Society for Microbiology. All rights reserved.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-10 of 121

Refine your search

Type of publication: journal article (112); research review (5); conference paper (3)

Type of content: peer-reviewed (117); other academic/artistic (3)

Author/Editor: Lilja, Hans (66); Carlsson, Sigrid, 19 ... (27); Ulmert, David (18); Bjartell, Anders (17); Roobol, Monique J (12); Pettersson, Kim (10); show more...; Hugosson, Jonas, 195 ... (8); Vertosick, Emily A (8); Assel, Melissa (8); Björk, Thomas (7); Stattin, Pär (7); Manjer, Jonas (6); Taylor, A (5); Carlsson, Sigrid V (5); Becker, Charlotte (5); Kirk, J. (4); Davidson, R. (4); Cook, J. (4); Friedman, E. (4); Castro, E (4); Johansson, Robert (4); Taylor, L. (4); Nilsson, Peter (4); Harris, M. (4); Häggström, Christel (4); Teo, SH (4); Lubinski, J (4); Berglund, Göran (4); Liljegren, A (4); Evans, DG (4); Falconer, A (4); Gronberg, H (4); Kote-Jarai, Z (4); Cybulski, C (4); Wokolorczyk, D (4); Teixeira, MR (4); Hamdy, FC (4); Eeles, RA (4); Nicolai, N (4); McGrath, J (4); Andrews, L (4); Brady, AF (4); Johannsson, O (4); Rennert, G. (4); Domchek, S. (4); Walker, L. (4); Izatt, L. (4); Oosterwijk, JC (4); Brewer, C (4); Donaldson, A (4); show less...

University: Lund University (74); University of Gothenburg (42); Karolinska Institutet (14); Uppsala University (10); Umeå University (8); Chalmers University of Technology (2); show more...; Kristianstad University College (1); Halmstad University (1); Stockholm University (1); Örebro University (1); Swedish Museum of Natural History (1); show less...

Language: English (121)

Research subject (UKÄ/SCB): Medical and Health Sciences (104); Natural sciences (8); Engineering and Technology (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view