| 1. |
- Rodrigues, Dario B., et al.
(author)
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Radiofrequency and microwave hyperthermia in cancer treatment
- 2021
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In: Principles and Technologies for Electromagnetic Energy Based Therapies. ; , s. 281-311
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Book chapter (other academic/artistic)abstract
- Hyperthermia therapy involves mild heating (40-44°C) that has been shown to be a potent enhancer of radiation and chemotherapy. Microwave (MW) and radiofrequency (RF) hyperthermia devices provide a variety of heating approaches that can treat most cancers regardless of their size and depth. This review introduces the physics of MW/RF hyperthermia, the current state-of-the-art systems for both local and regional heating, and recent advancements in hyperthermia treatment planning and guidance using real-time magnetic resonance imaging. The clinical evidence from clinical trials involving RF/MW hyperthermia as an adjuvant for radiation and chemotherapy is reviewed to show that adequate heating can be obtained with state-of-the-art systems. These studies strongly support the use of adjuvant hyperthermia as it significantly improves curative and palliative clinical outcomes. We anticipate that recent technology advances will improve the treatment delivery and reduce its complexity, as pivotal components for expanding the use of hyperthermia at medical and radiation oncology centers and enhancing cancer therapy.
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| 2. |
- Tesarik, Jan, et al.
(author)
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Non-invasive Thermometry During Hyperthermia Using Differential Microwave Imaging Approach
- 2021
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In: 2021 15TH EUROPEAN CONFERENCE ON ANTENNAS AND PROPAGATION (EUCAP). - 2164-3342.
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Conference paper (peer-reviewed)abstract
- The evaluation of non-invasive microwave thermometry using a differential microwave imaging approach is investigated in an experimental setup. The setup consists of a monopole microwave tomographic system, a muscle phantom, and a circulation/heating system. The saline solution is used as the heated medium inside the muscle phantom. Based on Born Approximation and regularization by TSVD we reconstructed the distribution of both dielectric parameters, relative permittivity and electrical conductivity inside the investigation area. A promising agreement between measured and reconstructed electrical conductivity was achieved and some specifics for future improvement of microwave thermometry were identified.
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| 4. |
- Dobsicek Trefna, Hana, 1979, et al.
(author)
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Time-reversal focusing in microwave hyperthermia for deep-seated tumors
- 2010
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In: Physics in Medicine and Biology. - : IOP Publishing. - 0031-9155 .- 1361-6560. ; 55:8, s. 2167-2185
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Journal article (peer-reviewed)abstract
- A fast beam-forming method for hyperthermia treatment of deep-seated tumors is described and verified. The approach is based on the time-reversal characteristics of Maxwell equations. The basic principle of the method is coupling of the electromagnetic modeling of the system with the actual application. In this modeling the wavefront of the source is propagated through a patient-specific model from a virtual antenna placed in the tumor of the model. The simulated radiated field is then captured using a computer model of the surrounding antenna system. The acquired amplitudes and phases are then used in the real antenna system. The effectiveness of this procedure is demonstrated by calculating the power absorption distribution using FDTD electromagnetic simulations of a realistic 2D breast model as well as a 2D neck model. Several design parameters, i.e. number of antennas, operating frequency and dimensions, have been evaluated by performance indicators. The promising results suggest that the development of this technique is pursued further.
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| 6. |
- Fojtik, Pavel, et al.
(author)
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Technical recommendations for thyroid dose rate measurements made by members of the public
- 2019
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In: Radiation Measurements. - : Elsevier BV. - 1350-4487. ; 128
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Journal article (peer-reviewed)abstract
- Technical recommendations in respect of the thyroid dose rate measurements potentially carried out by members of the public in case of nuclear power plant accident are elaborated based on theoretical considerations and practical experiences with instruments offered to the public for “radioactivity measurements”. Practical advices are given on how to make and interpret the measurements as simply and reliably as possible. The recommendations should be conveyed to the interested individuals and groups by radiation protection professionals.
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