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Träfflista för sökning "WFRF:(Wallberg Anders) "

Search: WFRF:(Wallberg Anders)

  • Result 1-10 of 47
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  • Adrian Meredith, Jenny, 1971-, et al. (author)
  • Design and synthesis of novel P2 substituents in diol-based HIV protease inhibitors
  • 2010
  • In: European Journal of Medicinal Chemistry. - : Elsevier BV. - 0223-5234 .- 1768-3254. ; 45:1, s. 160-170
  • Journal article (peer-reviewed)abstract
    • The synthesis and SAR of HIV-1 protease inhibitors containing novel P2 structural elements are presented. The inhibitors were designed having hydrogen bond accepting P2 substituents to probe potential favorable interactions to Asp-29/Asp-30 of the HIV-1 protease backbone utilizing inhibitor 3 as a model template. Several inhibitors were synthesized from an L-Val methyl amide P2 motif by appending hydrogen bonding moieties from either the isopropyl side-chain or from the methyl amide portion. The most promising inhibitors 4a and 4e displayed K-i values of 1.0 nM and 0.7 nM respectively and EC50 values in the MT4 cell-based assay of 0.17 mu M and 0.33 mu M respectively, a slight loss in potency compared to lead inhibitor 3. These inhibitors were also tested against an HIV protease inhibitor resistant strain carrying the M461, V82F, and 184V mutations. Inhibitors 4a and 4e displayed a 3 and 4 fold change respectively compared with HIV wild type, whereas lead inhibitor 3 showed a higher 9 fold change. This study further demonstrate the chemical tractability of the approach where various P2 substituents can be introduced in just one chemical step from lactone 21 enabling facile modifications of the overall properties in this inhibitor class.
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  • Arkell, Anders, et al. (author)
  • Extraction of Lignin from Kraft Black Liquor by Membrane Filtration
  • 2014
  • In: [Host publication title missing]. ; , s. 219-220
  • Conference paper (other academic/artistic)abstract
    • Lignin from black liquor in the kraft pulping process is a potential raw material for production of renewable chemicals and fuels. However, an efficient extraction method for the lignin from the black liquor is needed. Therefore, two new processes have been designed, which both utilize membrane filtration for the isolation of lignin from the kraft black liquor. The first one includes precipitation and filtration for the production of a solid lignin, while the second involves a base-catalysed reaction and organic-solvent extraction for the production of a precursor for liquid fuels.
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  • Arkell, Anders, et al. (author)
  • Increasing flux by back-pulsing in the microfiltration of milk
  • 2015
  • In: International Dairy Journal. - : Elsevier BV. - 0958-6946. ; 41, s. 23-25
  • Journal article (peer-reviewed)abstract
    • Milk with extended shelf-life can be produced by microfiltration (MF) and pasteurisation in a cascade arrangement. In a previous study, we have shown that back-pulsing can be used to reduce the energy requirement in the MF of defatted milk. In this study, the influence of back-pulsing on MF was investigated at higher milk fluxes than in a prior study. The MF experiments were performed in constant-flux mode. The operational time until a certain pressure build-up was used as a measure of the performance. Fluxes between 350 and 500 L m−2 h−1 were investigated, with and without back-pulsing (frequencies ranging from 6 to 0.2 min−1). It was shown that the fouling rate was strongly dependent on the permeate flux; higher flux leading to a higher fouling rate. Improved MF performance was found using back-pulsing at a flux of 350 L m−2 h−1, while at higher fluxes, back-pulsing impaired the performance.
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  • Result 1-10 of 47
Type of publication
journal article (22)
conference paper (15)
reports (5)
book chapter (3)
book (2)
Type of content
peer-reviewed (31)
other academic/artistic (15)
pop. science, debate, etc. (1)
Author/Editor
Wallberg, Anders (15)
Wallberg, Ola (15)
Hallberg, Anders (11)
Samuelsson, Bertil (11)
Wallberg, Hans (11)
Arkell, Anders (9)
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Larhed, Mats (6)
Unge, Torsten (6)
Jönsson, Ann-Sofi (5)
Olsson, Johanna (5)
Al-Rudainy, Basel (4)
Vrang, Lotta (3)
Ahlgren, Serina (3)
Hansson, Per-Anders (3)
Sandgren, Mats (3)
Stigsson, Lars (3)
Wallberg-Jonsson, So ... (3)
Rydberg, Annika (2)
Abrahamsson, Lena (2)
Veibäck, Torgny (2)
Ekbom, Anders (2)
Fernlund, Eva (2)
Wahren-Herlenius, Ma ... (2)
Theander, Elke (2)
Jansson, Katarina (2)
Rosenquist, Åsa (2)
Alfredsson, Lars (2)
Winqvist, Ola (2)
Karlsson Potter, Han ... (2)
Johansson, Åsa (2)
Salomonsson, Stina (2)
Sonesson, Sven-Erik (2)
Classon, Björn (2)
Kvarnström, Ingemar (2)
Ambrosi, Aurelie (2)
Zeffer, Elisabeth (2)
Dzikaite, Vijole (2)
Bergman, Gunnar (2)
Skogh, Thomas (2)
Mellander, Mats (2)
Fored, Michael (2)
Gadler, Fredrik (2)
Eliasson, Hakan (2)
Ohman, Annika (2)
Lundstrom, Ulla (2)
Kallberg, Henrik (2)
Jonzon, Anders (2)
Bullock, Adrian (2)
Ayesa, Susana (2)
Passoth, Volkmar (2)
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University
Lund University (17)
Uppsala University (12)
RISE (10)
Södertörn University (3)
University of Gothenburg (2)
Luleå University of Technology (2)
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Stockholm University (2)
Linköping University (2)
Karolinska Institutet (2)
Swedish University of Agricultural Sciences (2)
Umeå University (1)
Högskolan Dalarna (1)
Blekinge Institute of Technology (1)
IVL Swedish Environmental Research Institute (1)
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Language
English (41)
Swedish (5)
Undefined language (1)
Research subject (UKÄ/SCB)
Engineering and Technology (16)
Natural sciences (11)
Medical and Health Sciences (11)
Social Sciences (3)
Agricultural Sciences (1)

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