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Search: WFRF:(Wong Piu)

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  • Hattangadi, Shilpa M., et al. (author)
  • From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications
  • 2011
  • In: Blood. - : American Society of Hematology. - 1528-0020 .- 0006-4971. ; 118:24, s. 6258-6268
  • Research review (peer-reviewed)abstract
    • This article reviews the regulation of production of RBCs at several levels. We focus on the regulated expansion of burst-forming unit-erythroid erythroid progenitors by glucocorticoids and other factors that occur during chronic anemia, inflammation, and other conditions of stress. We also highlight the rapid production of RBCs by the coordinated regulation of terminal proliferation and differentiation of committed erythroid colony-forming unit-erythroid progenitors by external signals, such as erythropoietin and adhesion to a fibronectin matrix. We discuss the complex intracellular networks of coordinated gene regulation by transcription factors, chromatin modifiers, and miRNAs that regulate the different stages of erythropoiesis. (Blood. 2011;118(24):6258-6268)
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  • Result 1-1 of 1
Type of publication
research review (1)
Type of content
peer-reviewed (1)
Author/Editor
Flygare, Johan (1)
Lodish, Harvey F. (1)
Hattangadi, Shilpa M ... (1)
Wong, Piu (1)
Zhang, Lingbo (1)
University
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2011 (1)

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