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1.	Niemi, MEK, et al. (author) 2021 swepub:Mat__t
2.	Kanai, M, et al. (author) 2023 swepub:Mat__t
3.	Ong, KL, et al. (author) Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 2023 In: Lancet (London, England). - 1474-547X .- 0140-6736. ; 402:10397, s. 203-234 Journal article (peer-reviewed)
4.	Dewa Ayu Ratna Dewanti, I., et al. (author) Bones, scales of Upeneus sulphureus and Osphronemus gouramy increase adhesion and decrease IL-1β expression on monocytes against Streptococcus mutans 2020 In: Annals of Tropical Medicine and Public Health. - : Wolters Kluwer. - 1755-6783 .- 0974-6005. ; 23:8, s. 1253-1258 Journal article (peer-reviewed)abstract Adhesion and IL-1β on cells imunocompetent are important to prevent the spread of Streptococcus mutans infection to the systemic. One of the efforts is to use bones, fish scales Upeneus sulphureus and Osphronemus gouramy, they suspected contain of immunomodulator components. This study aims to analyze the effect of bone, scales of U. sulphureus and O. gouramy on adhesion activity and IL-1β expression on monocytes against S. mutans. This in vivo experimental study using the post test only control group design. Peripheral blood that has been layered with ficoll hypaque, then it added HBSS, Fungizone and Penstripe. The cells were placed in well microtiter plate, then they treated according to groups. Adhesion was stained with Giemza, IL-1β was stained with immunocytochemical. Cells were counted under a light microscope with magnification 400 times per 100 cells. The data obtained were analyzed using ANOVA followed by LSD test. Post test only design and the data obtained were analyzed using ANOVA followed by LSD test. There were no significant differences (p < 0.05) between Bones and scales. They both increase the adhesion of S. mutans and decrease the expression of IL-1β in monocytes. Bone and scales U. ulphureus and O. gouramy increase the recognition of monocytes to S. mutans and inhibit the spread of infection to systemic.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Brown, J. (2); Clark, A. (2); Cole, S. (2); Davies, M. (2); Endo, M. (2); Erdmann, J. (2); show more...; Fox, H. (2); Hasegawa, Y. (2); Hughes, G. (2); Jackson, M. (2); Jackson, P. (2); Karthik, K. (2); Lee, H. (2); Lewis, A. (2); Maeno, T. (2); Saleem, M. (2); Suzuki, Y. (2); Walker, R. (2); Wang, C. (2); White, S. (2); Williams, S. (2); Wilson, A. (2); Wright, M. (2); Wu, Y. (2); Yamada, M. (2); Nagata, K. (2); Davidson, N. (2); Dobson, E. (2); Harvey, A. (2); Lange, C. (2); Oliveira, M. (2); Rose, A. (2); Davies, E. (2); Grau, N. (2); Haider, S. (2); Tokunaga, K. (2); Suzuki, S (2); Gupta, A. (2); Robinson, M. (2); Dennis, C. (2); Marshall, R. (2); Smith, M. (2); Martin, J. (2); Mbarek, H (2); Davies, G (2); Harris, C (2); Kumar, S (2); Brown, A. (2); Brown, E. (2); Clark, M. (2); show less...

University: Karolinska Institutet (2); University of Gothenburg (1); Linnaeus University (1); Högskolan Dalarna (1)

Language: English (4)

Research subject (UKÄ/SCB): Natural sciences (1); Medical and Health Sciences (1)

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