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- Niemi, MEK, et al.
(author)
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- 2021
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swepub:Mat__t
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- Kanai, M, et al.
(author)
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- 2023
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swepub:Mat__t
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- Dewa Ayu Ratna Dewanti, I., et al.
(author)
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Bones, scales of Upeneus sulphureus and Osphronemus gouramy increase adhesion and decrease IL-1β expression on monocytes against Streptococcus mutans
- 2020
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In: Annals of Tropical Medicine and Public Health. - : Wolters Kluwer. - 1755-6783 .- 0974-6005. ; 23:8, s. 1253-1258
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Journal article (peer-reviewed)abstract
- Adhesion and IL-1β on cells imunocompetent are important to prevent the spread of Streptococcus mutans infection to the systemic. One of the efforts is to use bones, fish scales Upeneus sulphureus and Osphronemus gouramy, they suspected contain of immunomodulator components. This study aims to analyze the effect of bone, scales of U. sulphureus and O. gouramy on adhesion activity and IL-1β expression on monocytes against S. mutans. This in vivo experimental study using the post test only control group design. Peripheral blood that has been layered with ficoll hypaque, then it added HBSS, Fungizone and Penstripe. The cells were placed in well microtiter plate, then they treated according to groups. Adhesion was stained with Giemza, IL-1β was stained with immunocytochemical. Cells were counted under a light microscope with magnification 400 times per 100 cells. The data obtained were analyzed using ANOVA followed by LSD test. Post test only design and the data obtained were analyzed using ANOVA followed by LSD test. There were no significant differences (p < 0.05) between Bones and scales. They both increase the adhesion of S. mutans and decrease the expression of IL-1β in monocytes. Bone and scales U. ulphureus and O. gouramy increase the recognition of monocytes to S. mutans and inhibit the spread of infection to systemic.
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