1. |
- Kristanl, Matej, et al.
(author)
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The Seventh Visual Object Tracking VOT2019 Challenge Results
- 2019
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In: 2019 IEEE/CVF INTERNATIONAL CONFERENCE ON COMPUTER VISION WORKSHOPS (ICCVW). - : IEEE COMPUTER SOC. - 9781728150239 ; , s. 2206-2241
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Conference paper (peer-reviewed)abstract
- The Visual Object Tracking challenge VOT2019 is the seventh annual tracker benchmarking activity organized by the VOT initiative. Results of 81 trackers are presented; many are state-of-the-art trackers published at major computer vision conferences or in journals in the recent years. The evaluation included the standard VOT and other popular methodologies for short-term tracking analysis as well as the standard VOT methodology for long-term tracking analysis. The VOT2019 challenge was composed of five challenges focusing on different tracking domains: (i) VOT-ST2019 challenge focused on short-term tracking in RGB, (ii) VOT-RT2019 challenge focused on "real-time" short-term tracking in RGB, (iii) VOT-LT2019 focused on long-term tracking namely coping with target disappearance and reappearance. Two new challenges have been introduced: (iv) VOT-RGBT2019 challenge focused on short-term tracking in RGB and thermal imagery and (v) VOT-RGBD2019 challenge focused on long-term tracking in RGB and depth imagery. The VOT-ST2019, VOT-RT2019 and VOT-LT2019 datasets were refreshed while new datasets were introduced for VOT-RGBT2019 and VOT-RGBD2019. The VOT toolkit has been updated to support both standard short-term, long-term tracking and tracking with multi-channel imagery. Performance of the tested trackers typically by far exceeds standard baselines. The source code for most of the trackers is publicly available from the VOT page. The dataset, the evaluation kit and the results are publicly available at the challenge website(1).
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2. |
- Feng, Hongliang, et al.
(author)
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Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study
- 2023
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In: Nature Communications. - : Springer Nature. - 2041-1723. ; 14:1
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Journal article (peer-reviewed)abstract
- There is a growing interest in the role of timing of daily behaviors in improving health. However, little is known about the optimal timing of physical activity to maximize health benefits. We perform a cohort study of 92,139 UK Biobank participants with valid accelerometer data and all-cause and cause-specific mortality outcomes, comprising over 7 years of median follow-up (638,825 person-years). Moderate-to-vigorous intensity physical activity (MVPA) at any time of day is associated with lower risks for all-cause, cardiovascular disease, and cancer mortality. In addition, compared with morning group (>50% of daily MVPA during 05:00-11:00), midday-afternoon (11:00-17:00) and mixed MVPA timing groups, but not evening group (17:00-24:00), have lower risks of all-cause and cardiovascular disease mortality. These protective associations are more pronounced among the elderly, males, less physically active participants, or those with preexisting cardiovascular diseases. Here, we show that MVPA timing may have the potential to improve public health.
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3. |
- Jia, Xiaoyu, et al.
(author)
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Chemical and Structural Engineering of Gelatin-Based Delivery Systems for Therapeutic Applications : A Review
- 2024
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In: Biomacromolecules. - : American Chemical Society (ACS). - 1525-7797 .- 1526-4602. ; 25:2, s. 564-589
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Research review (peer-reviewed)abstract
- As a biodegradable and biocompatible protein derived from collagen, gelatin has been extensively exploited as a fundamental component of biological scaffolds and drug delivery systems for precise medicine. The easily engineered gelatin holds great promise in formulating various delivery systems to protect and enhance the efficacy of drugs for improving the safety and effectiveness of numerous pharmaceuticals. The remarkable biocompatibility and adjustable mechanical properties of gelatin permit the construction of active 3D scaffolds to accelerate the regeneration of injured tissues and organs. In this Review, we delve into diverse strategies for fabricating and functionalizing gelatin-based structures, which are applicable to gene and drug delivery as well as tissue engineering. We emphasized the advantages of various gelatin derivatives, including methacryloyl gelatin, polyethylene glycol-modified gelatin, thiolated gelatin, and alendronate-modified gelatin. These derivatives exhibit excellent physicochemical and biological properties, allowing the fabrication of tailor-made structures for biomedical applications. Additionally, we explored the latest developments in the modulation of their physicochemical properties by combining additive materials and manufacturing platforms, outlining the design of multifunctional gelatin-based micro-, nano-, and macrostructures. While discussing the current limitations, we also addressed the challenges that need to be overcome for clinical translation, including high manufacturing costs, limited application scenarios, and potential immunogenicity. This Review provides insight into how the structural and chemical engineering of gelatin can be leveraged to pave the way for significant advancements in biomedical applications and the improvement of patient outcomes.
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4. |
- Jin, Xinyi, et al.
(author)
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Association of accelerometer-measured sleep duration and different intensities of physical activity with incident type 2 diabetes in a population-based cohort study.
- 2023
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In: Journal of Sport and Health Science. - : Elsevier BV. - 2095-2546 .- 2213-2961.
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Journal article (peer-reviewed)abstract
- PURPOSE: The aim of the current study was to investigate the association of accelerometer-measured sleep duration and different intensities of physical activity (PA) with the risk of incident type 2 diabetes in a population-based prospective cohort study.METHODS: Altogether, 88,000 participants (mean age = 62.2 ± 7.9 years, mean ± SD) were included from the UK Biobank. Sleep duration (short: <6 h/day; normal: 6-8 h/day; long: >8 h/day) and PA of different intensities were measured using a wrist-worn accelerometer over a 7-day period between 2013 and 2015. PA was classified according to the median or World Health Organization-recommendation: total volume of PA (high, low), moderate-to-vigorous PA (MVPA) (recommended, not recommended), and light-intensity PA (high, low). Incidence of type 2 diabetes was ascertained using hospital records or death registries.RESULTS: During a median follow-up of 7.0 years, 1615 incident type 2 diabetes cases were documented. Compared with normal sleep duration, short (hazard ratio (HR) = 1.21, 95% confidence interval (95%CI): 1.03-1.41) but not long sleep duration (HR = 1.01, 95%CI: 0.89-1.15) was associated with excessive type 2 diabetes risk. This increased risk among short sleepers seems to be protected against by PA. Compared with normal sleepers with high or recommended PA, short sleepers with low volume of PA (HR = 1.81, 95%CI: 1.46-2.25), not recommended (below the World Health Organization-recommended level of) moderate-to-vigorous PA (HR = 1.92, 95%CI: 1.55-2.36), or low light-intensity PA (HR = 1.49, 95%CI: 1.13-1.90) had a higher risk of type 2 diabetes, while short sleepers with a high volume of PA (HR = 1.14, 95%CI: 0.88-1.49), recommended moderate-to-vigorous PA (HR = 1.02, 95%CI: 0.71-1.48), or high light-intensity PA (HR = 1.14, 95%CI: 0.92-1.41) did not.CONCLUSION: Accelerometer-measured short but not long sleep duration was associated with a higher risk of incident type 2 diabetes. A higher level of PA, regardless of intensity, potentially ameliorates this excessive risk.
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5. |
- Li, Hongliang, et al.
(author)
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Catalytic performance and characterization of Al2O3-supported Pt-Co catalyst coatings for preferential CO oxidation in a micro-reactor
- 2010
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In: Applied Catalysis A. - : Elsevier BV. - 0926-860X .- 1873-3875. ; 387:1-2, s. 215-223
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Journal article (peer-reviewed)abstract
- Platinum-cobalt (Pt-Co) catalyst coatings are studied for preferential oxidation of carbon monoxide (PROX) ill hydrogen-rich gas streams. Experimental results show a role for cobalt in improving catalytic activity. The most active catalyst coating can decrease carbon monoxide concentrations from 1% to a value of less than 10 ppm for GHSV values ranging from 40,000 to 120,000 ml g(-1) h(-1). This catalyst coating can work at a wide window of operation ill terms of temperature. Transmission electron microscopy, selected-area electron diffraction, and diffuse reflectance infrared Fourier transform spectroscopy show that the addition of Co forms Pt3Co intermetallic compounds and slightly increases the average particle size. In situ laser Raman spectroscopy reveals the co-existence of Co metal and its oxides on the catalyst surface, due to gradual oxidation of Co by gas phase oxygen within the initial stage of the PROX reaction. The promotional effect of Co during PROX is confirmed and ascribed to this Pt3Co intermetallic compound and the synergetic effect of Co-0 and Co chi+. The high accessibility of the reactant to Pt3Co species appears favorable and crucial for PROX.
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6. |
- Wang, Xiaoyu, et al.
(author)
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Associations of Insomnia With Insulin Resistance Traits : A Cross-sectional and Mendelian Randomization Study
- 2023
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In: Journal of Clinical Endocrinology and Metabolism. - : Endocrine Society. - 0021-972X .- 1945-7197. ; 108:8, s. e574-e582
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Journal article (peer-reviewed)abstract
- Context: Insomnia is associated with insulin resistance (IR) in observational studies; however, whether insomnia is causally associated with IR remains unestablished.Objective: This study aims to estimate the causal associations of insomnia with IR and its related traits.Methods: In primary analyses, multivariable regression (MVR) and 1-sample Mendelian randomization (1SMR) analyses were performed to estimate the associations of insomnia with IR (triglyceride-glucose index and triglyceride to high-density lipoprotein cholesterol [TG/HDL-C] ratio) and its related traits (glucose level, TG, and HDL-C) in the UK Biobank. Thereafter, 2-sample MR (2SMR) analyses were used to validate the findings from primary analyses. Finally, the potential mediating effects of IR on the pathway of insomnia giving rise to type 2 diabetes (T2D) were examined using a 2-step MR design.Results: Across the MVR, 1SMR, and their sensitivity analyses, we found consistent evidence suggesting that more frequent insomnia symptoms were significantly associated with higher values of triglyceride-glucose index (MVR, beta = 0.024, P < 2.00E-16; 1SMR, beta = 0.343, P < 2.00E-16), TG/HDL-C ratio (MVR, beta = 0.016, P = 1.75E-13; 1SMR, beta = 0.445, P < 2.00E-16), and TG level (MVR, beta = 0.019 log mg/dL, P < 2.00E-16, 1SMR: beta = 0.289 log mg/dL, P < 2.00E-16) after Bonferroni adjustment. Similar evidence was obtained by using 2SMR, and mediation analysis suggested that about one-quarter (25.21%) of the association between insomnia symptoms and T2D was mediated by IR.Conclusions: This study provides robust evidence supporting that more frequent insomnia symptoms are associated with IR and its related traits across different angles. These findings indicate that insomnia symptoms can be served as a promising target to improve IR and prevent subsequent T2D.
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7. |
- Wang, Yanan, et al.
(author)
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The radio detection and accretion properties of the peculiar nuclear transient AT 2019avd
- 2023
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In: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 520:2, s. 2417-2435
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Journal article (peer-reviewed)abstract
- AT 2019avd is a nuclear transient detected from infrared to soft X-rays, though its nature is yet unclear. The source has shown two consecutive flaring episodes in the optical and the infrared bands, and its second flare was covered by X-ray monitoring programs. During this flare, the UVOT/Swift photometries revealed two plateaus: one observed after the peak and the other one appeared similar to 240 d later. Meanwhile, our NICER and XRT/Swift campaigns show two declines in the X-ray emission, one during the first optical plateau and one 70-90 d after the optical/UV decline. The evidence suggests that the optical/UV could not have been primarily originated from X-ray reprocessing. Furthermore, we detected a timelag of similar to 16-34 d between the optical and UV emission, which indicates the optical likely comes from UV reprocessing by a gas at a distance of 0.01-0.03 pc. We also report the first VLA and VLBA detection of this source at different frequencies and different stages of the second flare. The information obtained in the radio band - namely a steep and a late-time inverted radio spectrum, a high brightness temperature and a radio-loud state at late times - together with the multiwavelength properties of AT 2019avd suggests the launching and evolution of outflows such as disc winds or jets. In conclusion, we propose that after the ignition of black hole activity in the first flare, a super-Eddington flaring accretion disc formed and settled to a sub-Eddington state by the end of the second flare, associated with a compact radio outflow.
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8. |
- Ying, Qianwen, et al.
(author)
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Highly stable measurement for nanoparticle extinction cross section by analyzing aperture-edge blurriness
- 2021
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In: Optics Express. - : Optical Society of America. - 1094-4087. ; 29:11, s. 16323-16333
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Journal article (peer-reviewed)abstract
- In order to stabilize the extinction cross section measurement of a single nanoparticle, we propose to analyze the blurriness parameter of aperture edge images in real time, which provides a feedback to lock the sample position. Unlike the conventional spatial modulation spectroscopy (SMS) technique, a probe beam experiences both the spatial modulation by a piezo stage and the temporal modulation by a chopper. We experimentally demonstrate that the measurement uncertainty is one order magnitude less than that in the previous report. The proposed method can be readily implemented in conventional SMS systems and can help to achieve high stability for sensing based on light extinction by a single nanoparticle, which alleviate the impact from laboratory environment and increase the experimental sensitivity.
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9. |
- Ying, Qianwen, et al.
(author)
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Highly stable measurement for nanoparticle extinction cross section by analyzing aperture-edge blurriness
- 2021
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In: Optics Express. - : Optical Society of America. - 1094-4087. ; 29:11, s. 16323-16323
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Journal article (peer-reviewed)abstract
- In order to stabilize the extinction cross section measurement of a single nanoparticle, we propose to analyze the blurriness parameter of aperture edge images in real time, which provides a feedback to lock the sample position. Unlike the conventional spatial modulation spectroscopy (SMS) technique, a probe beam experiences both the spatial modulation by a piezo stage and the temporal modulation by a chopper. We experimentally demonstrate that the measurement uncertainty is one order magnitude less than that in the previous report. The proposed method can be readily implemented in conventional SMS systems and can help to achieve high stability for sensing based on light extinction by a single nanoparticle, which alleviate the impact from laboratory environment and increase the experimental sensitivity.
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10. |
- Yu, Xinhai, et al.
(author)
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Pt-Co catalyst-coated channel plate reactor for preferential CO oxidation
- 2011
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In: International journal of hydrogen energy. - : Elsevier BV. - 0360-3199 .- 1879-3487. ; 36:5, s. 3778-3788
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Journal article (peer-reviewed)abstract
- To achieve preferential CO oxidation, a Pt-Co catalyst-coated channel plate reactor (CCPR) was produced via conventional mechanical milling and catalyst coating. The proposed reactor performed well under a wide range of operating temperatures and provided satisfactory results at low temperatures (CO concentrations of 1-10 ppm at 413-443 K and 1-50 ppm at 413-453 K). In the proposed CCPR, significant deactivation was not observed during continuous operation for 100 h. In addition, the reactor exhibited excellent tolerance to undesirable conditions, including reaction temperature runaway and feeding stream failure. Characterisation results indicated that the catalytic activity of the proposed CCPR was high due to the formation of Pt3Co intermetallic compounds and nanoscale metal particles. The capacity per channel of the proposed CCPR was approximately 50-100 times greater than those of conventional microchannel reactors; thus, problems associated with excessive reactors were significantly reduced. In general, the results indicated that CCPR has great potential in the small-scale production of hydrogen for fuel cells.
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