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Träfflista för sökning "WFRF:(Zhao BB) "

Search: WFRF:(Zhao BB)

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  • Kinyoki, DK, et al. (author)
  • Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
  • 2020
  • In: Nature medicine. - : Springer Science and Business Media LLC. - 1546-170X .- 1078-8956. ; 26:5, s. 750-759
  • Journal article (peer-reviewed)abstract
    • A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic.
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  • Callaway, EM, et al. (author)
  • A multimodal cell census and atlas of the mammalian primary motor cortex
  • 2021
  • In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 598:7879, s. 86-102
  • Journal article (peer-reviewed)abstract
    • Here we report the generation of a multimodal cell census and atlas of the mammalian primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network (BICCN). This was achieved by coordinated large-scale analyses of single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved single-cell transcriptomes, morphological and electrophysiological properties and cellular resolution input–output mapping, integrated through cross-modal computational analysis. Our results advance the collective knowledge and understanding of brain cell-type organization1–5. First, our study reveals a unified molecular genetic landscape of cortical cell types that integrates their transcriptome, open chromatin and DNA methylation maps. Second, cross-species analysis achieves a consensus taxonomy of transcriptomic types and their hierarchical organization that is conserved from mouse to marmoset and human. Third, in situ single-cell transcriptomics provides a spatially resolved cell-type atlas of the motor cortex. Fourth, cross-modal analysis provides compelling evidence for the transcriptomic, epigenomic and gene regulatory basis of neuronal phenotypes such as their physiological and anatomical properties, demonstrating the biological validity and genomic underpinning of neuron types. We further present an extensive genetic toolset for targeting glutamatergic neuron types towards linking their molecular and developmental identity to their circuit function. Together, our results establish a unifying and mechanistic framework of neuronal cell-type organization that integrates multi-layered molecular genetic and spatial information with multi-faceted phenotypic properties.
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  • Result 1-10 of 37
Type of publication
journal article (31)
conference paper (3)
research review (1)
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peer-reviewed (32)
other academic/artistic (3)
Author/Editor
Jonas, JB (16)
Mokdad, AH (16)
Singh, JA (16)
Yonemoto, N (16)
Khan, EA (15)
Violante, FS (15)
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Antonio, CAT (14)
Fischer, F (14)
Hay, SI (14)
Miller, TR (14)
Oh, IH (14)
Olusanya, BO (14)
Tran, BX (14)
Yip, P (14)
Murray, CJL (14)
Gupta, R. (13)
Alvis-Guzman, N (13)
Castaneda-Orjuela, C ... (13)
Dandona, L (13)
Dandona, R (13)
Dharmaratne, SD (13)
Fereshtehnejad, SM (13)
Koyanagi, A (13)
Kumar, GA (13)
Mendoza, W (13)
Monasta, L (13)
Nangia, V (13)
Schwebel, DC (13)
Sepanlou, SG (13)
Shaikh, MA (13)
Venketasubramanian, ... (13)
Younis, MZ (13)
Yu, CH (13)
Liu, Y. (12)
Abd-Allah, F (12)
Basu, S (12)
Bedi, N (12)
Cardenas, R (12)
Farzadfar, F (12)
Hafezi-Nejad, N (12)
Hamadeh, RR (12)
Khader, YS (12)
Radfar, A (12)
Ronfani, L (12)
Shibuya, K (12)
Singh, A (12)
Sreeramareddy, CT (12)
Tabares-Seisdedos, R (12)
Vos, T (12)
Wang, YP (12)
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Karolinska Institutet (36)
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Uppsala University (10)
Lund University (10)
University of Gothenburg (4)
Umeå University (3)
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Linköping University (2)
Royal Institute of Technology (1)
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English (37)
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