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- Thomas, HS, et al.
(author)
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- 2019
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swepub:Mat__t
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4. |
- Abdullah, Jakaria, et al.
(author)
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Towards a Tool : TIMES-Pro for Modeling, Analysis, Simulation and Implementation of Cyber-Physical Systems
- 2017
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In: MODELS, ALGORITHMS, LOGICS AND TOOLS. - Cham : SPRINGER INTERNATIONAL PUBLISHING AG. - 9783319631219 - 9783319631202 ; , s. 623-639
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Conference paper (peer-reviewed)abstract
- We consider a Cyber-Physical System (CPS) as a network of components that are either physical plants with continuous behaviors or discrete controllers. To build CPS's in a systematic manner, the TIMES-Pro tool is designed to support modeling, analysis and code generation for real-time simulation and final deployment. In this paper, we present our decisions in designing the modeling language, the tool architecture and features of TIMES-Pro, and also a case study to demonstrate its applicability.
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5. |
- Guan, Nan, et al.
(author)
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Scalable timing analysis with refinement
- 2015
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In: Tools and Algorithms for the Construction and Analysis of Systems. - Berlin, Heidelberg : Springer. - 9783662466803 ; , s. 3-18
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Conference paper (peer-reviewed)
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7. |
- Vallejo-Vaz, Antonio J., et al.
(author)
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Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration
- 2016
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In: Atherosclerosis Supplements. - : ELSEVIER IRELAND LTD. - 1567-5688 .- 1878-5050. ; 22
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Journal article (peer-reviewed)abstract
- Background: The potential for global collaborations to better inform public health policy regarding major non-hypercholesterolaemia (FH), a common genetic disorder associated with premature cardiovascular disease, is yet to be reliably ascertained using similar approaches. The European Atherosclerosis Society FH Studies Collaboration (EAS FHSC) is a new initiative of international stakeholders which will help establish a global FH registry to generate large-scale, robust data on the burden of FH worldwide. Methods: The EAS FHSC will maximise the potential exploitation of currently available and future FH data (retrospective and prospective) by bringing together regional/national/international data sources with access to individuals with a clinical and/or genetic diagnosis of heterozygous or homozygous FH. A novel bespoke electronic platform and FH Data Warehouse will be developed to allow secure data sharing, validation, cleaning, pooling, harmonisation and analysis irrespective of the source or format. Standard statistical procedures will allow us to investigate cross-sectional associations, patterns of real-world practice, trends over time, and analyse risk and outcomes (e.g. cardiovascular outcomes, all-cause death), accounting for potential confounders and subgroup effects. Conclusions: The EAS FHSC represents an excellent opportunity to integrate individual efforts across the world to tackle the global burden of FH. The information garnered from the registry will help reduce gaps in knowledge, inform best practices, assist in clinical trials design, support clinical guidelines and policies development, and ultimately improve the care of FH patients. (C) 2016 Elsevier Ireland Ltd.
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