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1.
  • Wild, W., et al. (author)
  • Millimetron—a large Russian-European submillimeter space observatory
  • 2009
  • In: Experimental Astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 23:1, s. 221-244
  • Journal article (peer-reviewed)abstract
    • Millimetron is a Russian-led 12 m diameter submillimeter and far-infrared space observatory which is included in the Space Plan of the Russian Federation for launch around 2017. With its large collecting area and state-of-the-art receivers, it will enable unique science and allow at least one order of magnitude improvement with respect to the Herschel Space Observatory. Millimetron will be operated in two basic observing modes: as a single-dish observatory, and as an element of a ground-space very long baseline interferometry (VLBI) system. As single-dish, angular resolutions on the order of 3 to 12 arc sec will be achieved and spectral resolutions of up to a million employing heterodyne techniques. As VLBI antenna, the chosen elliptical orbit will provide extremely large VLBI baselines (beyond 300,000 km) resulting in micro-arc second angular resolution.
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2.
  • Wiedner, M.C., et al. (author)
  • Heterodyn receiver for the Origins Space Telescope concept 2
  • 2018
  • In: Proceedings of SPIE - The International Society for Optical Engineering. - : SPIE. - 0277-786X .- 1996-756X. ; 10698
  • Conference paper (peer-reviewed)abstract
    • The Origins Space Telescope (OST) is a NASA study for a large satellite mission to be submitted to the 2020 Decadal Review. The proposed satellite has a fleet of instruments including the HEterodyne Receivers for OST (HERO). HERO is designed around the quest to follow the trail of water from the ISM to disks around protostars and planets. HERO will perform high-spectral resolution measurements with 2x9 pixel focal plane arrays at any frequency between 468GHz to 2,700GHz (617 to 111 μm). HERO builds on the successful Herschel/HIFI heritage, as well as recent technological innovations, allowing it to surpass any prior heterodyne instrument in terms of sensitivity and spectral coverage.
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3.
  • Wiedner, M.C., et al. (author)
  • Heterodyne Receiver for Origins
  • 2021
  • In: Journal of Astronomical Telescopes, Instruments, and Systems. - 2329-4221 .- 2329-4124. ; 7:1
  • Journal article (peer-reviewed)abstract
    • The Heterodyne Receiver for Origins (HERO) is the first detailed study of a heterodyne focal plane array receiver for space applications. HERO gives the Origins Space Telescope the capability to observe at very high spectral resolution (R = 107) over an unprecedentedly large far-infrared (FIR) wavelengths range (111 to 617 μm) with high sensitivity, with simultaneous dual polarization and dual-frequency band operation. The design is based on prior successful heterodyne receivers, such as Heterodyne Instrument for the Far-Infrared/Herschel, but surpasses it by one to two orders of magnitude by exploiting the latest technological developments. Innovative components are used to keep the required satellite resources low and thus allowing for the first time a convincing design of a large format heterodyne array receiver for space. HERO on Origins is a unique tool to explore the FIR universe and extends the enormous potential of submillimeter astronomical spectroscopy into new areas of astronomical research.
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4.
  • Smirnov, A. V., et al. (author)
  • The Current Stage of Development of the Receiving Complex of the Millimetron Space Observatory
  • 2012
  • In: Radiophysics and Quantum Electronics (English Translation of Izvestiya Vysshikh Uchebnykh Zavedenii, Radiofizika). - : Springer Science and Business Media LLC. - 0033-8443 .- 1573-9120. ; 54:8-9, s. 557-568
  • Journal article (peer-reviewed)abstract
    • We present an overview of the state of the onboard receiving complex of the Millimetron space observatory in the development phase of its preliminary design. The basic parameters of the onboard equipment planned to create and required for astrophysical observations are considered. A review of coherent and incoherent detectors, which are central to each receiver of the observatory, is given. Their characteristics and limiting parameters feasible at the present level of technology are reported.
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5.
  • Barkhof, J., et al. (author)
  • ALMA Band 2 Receiver Automated Test System
  • 2022
  • In: 32nd International Symposium of Space Terahertz Technology, ISSTT 2022.
  • Conference paper (peer-reviewed)abstract
    • As part of the ALMA Band 2 project, an automated test system was developed to fully qualify state-of-the-art Band 2 receivers, based on heritage of the Band 9 and Band 5 productions. The RF range of this receiver is 67 - 116 GHz, with a goal IF band of 4-18 GHz. Each receiver will undergo a thorough acceptance testing to verify its operation and performance prior to delivery. The core of the test system are a single-cartridge test cryostat, a dual-channel intermediate frequency signal processor, a vector near-field test system, and script-based measurement and control software that enables automated testing. We present details of the test system and measurement results of the first Band 2 receivers.
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6.
  • Belitsky, Victor, 1955, et al. (author)
  • ALMA Band 2 Cold Cartridge Assembly Design
  • 2022
  • In: 32nd International Symposium of Space Terahertz Technology, ISSTT 2022.
  • Conference paper (peer-reviewed)abstract
    • As part of the ALMA development, we present the design of the ALMA Band 2 Cold Cartridge Assembly (CCA). The Band 2 is the last band that completes the suit of the 10 receiver channels of ALMA. The originally planned ALMA Band 2 receiver cartridge should cover the RF band of 67 - -90 GHz. The recent progress in technology, optics, OMT design and mm-wave amplifiers, however allowed to implement receiver that has an extended RF band up to 116 GHz. Furthermore, the Band 2 receiver pursues 2SB layout and provides 4-18 GHz IF band for two sidebands in a dual-polarization configuration. Here, we describe the design of the Band 2 CCA that includes optics, amplifier assembly, internal RF transport, mechanics and cryogenics. The downconverter part and performances are described elsewhere.
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7.
  • Belitsky, Victor, 1955, et al. (author)
  • SEPIA - A new single pixel receiver at the APEX telescope
  • 2018
  • In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 612
  • Journal article (peer-reviewed)abstract
    • Context. We describe the new Swedish-ESO PI Instrument for APEX (SEPIA) receiver, which was designed and built by the Group for Advanced Receiver Development (GARD), at Onsala Space Observatory (OSO) in collaboration with ESO. It was installed and commissioned at the APEX telescope during 2015 with an ALMA Band 5 receiver channel and updated with a new frequency channel (ALMA Band 9) in February 2016. Aim. This manuscript aims to provide, for observers who use the SEPIA receiver, a reference in terms of the hardware description, optics and performance as well as the commissioning results. Methods. Out of three available receiver cartridge positions in SEPIA, the two current frequency channels, corresponding to ALMA Band 5, the RF band 158-211 GHz, and Band 9, the RF band 600-722 GHz, provide state-of-the-art dual polarization receivers. The Band 5 frequency channel uses 2SB SIS mixers with an average SSB noise temperature around 45 K with IF (intermediate frequency) band 4-8 GHz for each sideband providing total 4 × 4 GHz IF band. The Band 9 frequency channel uses DSB SIS mixers with a noise temperature of 75-125 K with IF band 4-12 GHz for each polarization. Results. Both current SEPIA receiver channels are available to all APEX observers.
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8.
  • Wiedner, M.C., et al. (author)
  • A Proposed Heterodyne Receiver for the Origins Space Telescope
  • 2018
  • In: IEEE Transactions on Terahertz Science and Technology. - 2156-342X .- 2156-3446. ; 8:6, s. 558-571
  • Journal article (peer-reviewed)abstract
    • The HEterodyne Receiver for the Origins Space Telescope (HERO) is a proposed design for a heterodyne focal plane array for a large space mission. The Origins Space Telescope (OST) is one of the four missions selected to be studied by NASA for the 2020 Astronomy and Astrophysics Decadal survey. HERO is designed to observe the trail of water from the interstellar medium (ISM) to disks around protostars. In Concept 1, HERO provides continuous frequency coverage from 468 to 2700 GHz in five bands and a sixth band to cover 4700 GHz. Most bands include 2 × 64 pixels providing at least an order of magnitude higher mapping speeds than available with today's instruments. Receiver sensitivities are expected to be close to the quantum limit. HERO Concept 2, highly constrained by cost and denoted Little-HERO, includes four bands with continuous coverage from 486 to 2700 GHz and with focal plane arrays having only 2 × 9 pixels per band. Both of these THz receiver concepts will be described and the designs will be motivated by the science drivers, the space craft constraints and the latest technological developments. The HERO design builds on the highly successful Herschel/Heterodyne Instrument for the Far-Infrared, on Stratospheric Observatory for Far-Infrared Astronomy/upGREAT and many other heterodyne receivers, but surpasses these in terms of frequency coverage, array size and sensitivity, thanks to the latest technical advances. HERO can be considered an example of a new generation of heterodyne focal plane arrays for future space missions.
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9.
  • Wiedner, M.C., et al. (author)
  • The origins space telescope and the heterodyne receiver for origins (HERO)
  • 2019
  • In: ISSTT 2019 - 30th International Symposium on Space Terahertz Technology, Proceedings Book. ; , s. 204-207
  • Conference paper (peer-reviewed)abstract
    • The Origins Space Telescope is one of four large mission concept studies carried out by NASA for the 2020 Decadal survey. Origins is a far-infrared telescope designed to understand the evolution of galaxies and black holes, to follow the trail of water from protostars to habitable planets and to search for biosignatures in the atmospheres of exoplanets. The Heterodyne Receiver for Origins (HERO) is the high spectral resolution receiver. It is the first heterodyne array receiver designed to fly on a satellite and an example for possible future focal plane arrays for space. HERO has focal plane arrays with nine pixels in two polarization. HERO covers a large frequency range between 486 and 2700 GHz in only 4 frequency bands, requiring local oscillators with fractional bandwidth of 45%. HERO uses the best superconducting mixers with noise temperatures between 1 and 3 hf/k and an intermediate bandwidth of 6 to 8 GHz. HERO can carry out dual polarization and dual-frequency observations. The major challenges for the HERO design are the low cooling power and the low electrical power available on a spacecraft, which impact the choice of the cryogenic amplifiers and backends. SiGe cryogenic amplifiers with a consumption of less than 0.5 mW, as well as CMOS spectrometers with a power consumption below 2W are the baseline for HERO. The development plan includes broadband (45%) multiplier-amplifier chains, low noise mixers (1-3 hf/k), low-power consuming (< 05.mW) cryogenic amplifiers and low-power consuming spectrometer backends (< 2W).
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11.
  • Baryshev, M, et al. (author)
  • Unfolded protein response is involved in the pathology of human congenital hypothyroid goiter and rat non-goitrous congenital hypothyroidism
  • 2004
  • In: Journal of molecular endocrinology. - : Bioscientifica. - 0952-5041 .- 1479-6813. ; 32:3, s. 903-920
  • Journal article (peer-reviewed)abstract
    • The unfolded protein response (UPR) is an intracellular signaling pathway that regulates the protein folding and processing capacity of the endoplasmic reticulum (ER). The UPR is induced by the pharmacological agents that perturb ER functions but is also activated upon excessive accumulation of the mutant secretory proteins that are unable to attain correct three-dimensional structure and are thus retained in the ER. Such defects in intracellular protein transport underlie the development of a number of phenotypically diverse inherited pathologies, termed endoplasmic reticulum storage diseases (ERSD). We have studied UPR development in two similar ERSDs, human congenital goiter caused by the C1264R and C1996S mutations in the thyroglobulin (Tg) gene and non-goitrous congenital hypothyroidism in rdw dwarf rats determined by the G2320R Tg mutation. In both cases, these mutations rendered Tg incapable of leaving the ER. A major ER chaperone immunoglobulin-binding protein (BiP), and a novel putative escort chaperone endoplasmic reticulum protein 29 KDa (ERp29) were found to be associated with Tg, which might be interpreted as the contribution of the quality control machinery to the previously shown retention of Tg in the ER. We have extended our earlier observations of ER chaperone induction with the identification of the additional ER (ERp29, ERp72, calreticulin, protein disulfide isomerase (PDI)), cytoplasmic (heat shock protein (HSP)70, HSP90) and mitochondrial (mtHSP70) upregulated chaperones and folding enzymes. Activation of the transcriptional arm of UPR, as judged by the appearance of the spliced (active) form of X-box binding protein (XBP1) and processed activating transcription factor 6 (ATF6) transcription factors was suggested to contribute to the overexpression of the ER chaperones. The processing of ATF6 was observed in both human and rat tissues with Tg mutations. Whereas, in human tissues, weak splicing of XBP1 mRNA was detected only in the C1264R mutant, all rat thyroids including wild-type contained significant amounts of the spliced form of XBP1 as opposed to human liver and rat brain tissues, implying the existence of a previously unknown tissue-specific regulation of XBP1 processing.
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20.
  • Tan, B. K., et al. (author)
  • Investigation of the performance of an SIS mixer with Nb-AlN-NBN tunnel junctions in the 780-950 GHz frequency band
  • 2018
  • In: 2018 29th IEEE International Symposium on Space Terahertz Technology, ISSTT 2018. ; , s. 139-142
  • Conference paper (peer-reviewed)abstract
    • In this paper, we present preliminary measured performance of an SIS mixer employing a Nb/AIN/NbN tunnel junction in the frequency range of 780-950 GHz range. The mixer design is an upgrade of the Carbon Heterodyne Array of the Max-Planck-Institute Plus (CHAMP+) mixer, coupled with an easy to fabricate smooth-walled horn. The noise temperature of the mixer is measured using the standard Y-factor method, but all the RF optics is enclosed in the cryostat. We use a rotating mirror in the cryostat to switch between a room temperature load and a 4 K blackbody load. With this method, we have measured a noise temperature of 330 K around 850 GHz, corrected for a mismatch between a reduced height rectangular waveguide at the input of the mixer block and a full height waveguide at the output of the horn. To remove this mismatch we now plan to redesign a new mixer chip with a full-height waveguide back-piece. The expected performance of the new mixer chip is also reported.
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