1. |
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2. |
- Beal, Jacob, et al.
(author)
-
Robust estimation of bacterial cell count from optical density
- 2020
-
In: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
-
Journal article (peer-reviewed)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
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3. |
- Kanoni, Stavroula, et al.
(author)
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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
- 2022
-
In: Genome biology. - : Springer Science and Business Media LLC. - 1474-760X .- 1465-6906 .- 1474-7596. ; 23:1
-
Journal article (peer-reviewed)abstract
- Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery.To expand our understanding of the underlying biological pathways and mechanisms controlling blood lipid levels, we leverage a large multi-ancestry meta-analysis (N=1,654,960) of blood lipids to prioritize putative causal genes for 2286 lipid associations using six gene prediction approaches. Using phenome-wide association (PheWAS) scans, we identify relationships of genetically predicted lipid levels to other diseases and conditions. We confirm known pleiotropic associations with cardiovascular phenotypes and determine novel associations, notably with cholelithiasis risk. We perform sex-stratified GWAS meta-analysis of lipid levels and show that 3-5% of autosomal lipid-associated loci demonstrate sex-biased effects. Finally, we report 21 novel lipid loci identified on the X chromosome. Many of the sex-biased autosomal and X chromosome lipid loci show pleiotropic associations with sex hormones, emphasizing the role of hormone regulation in lipid metabolism.Taken together, our findings provide insights into the biological mechanisms through which associated variants lead to altered lipid levels and potentially cardiovascular disease risk.
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4. |
- Sampson, Joshua N., et al.
(author)
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Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types
- 2015
-
In: Journal of the National Cancer Institute. - : Oxford University Press (OUP). - 0027-8874 .- 1460-2105. ; 107:12
-
Journal article (peer-reviewed)abstract
- Background: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites. Methods: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients. We apply novel mixed model methodology (GCTA) to this GWAS data to estimate the heritability of individual cancers, as well as the proportion of heritability attributable to cigarette smoking in smoking-related cancers, and the genetic correlation between pairs of cancers. Results: GWAS heritability was statistically significant at nearly all sites, with the estimates of array-based heritability, h(l)(2), on the liability threshold (LT) scale ranging from 0.05 to 0.38. Estimating the combined heritability of multiple smoking characteristics, we calculate that at least 24% (95% confidence interval [CI] = 14% to 37%) and 7% (95% CI = 4% to 11%) of the heritability for lung and bladder cancer, respectively, can be attributed to genetic determinants of smoking. Most pairs of cancers studied did not show evidence of strong genetic correlation. We found only four pairs of cancers with marginally statistically significant correlations, specifically kidney and testes (rho = 0.73, SE = 0.28), diffuse large B-cell lymphoma (DLBCL) and pediatric osteosarcoma (rho = 0.53, SE = 0.21), DLBCL and chronic lymphocytic leukemia (CLL) (rho = 0.51, SE = 0.18), and bladder and lung (rho = 0.35, SE = 0.14). Correlation analysis also indicates that the genetic architecture of lung cancer differs between a smoking population of European ancestry and a nonsmoking Asian population, allowing for the possibility that the genetic etiology for the same disease can vary by population and environmental exposures. Conclusion: Our results provide important insights into the genetic architecture of cancers and suggest new avenues for investigation.
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5. |
- Ablikim, M., et al.
(author)
-
Branching fraction measurement of J/ψ→KSKL and search for J/ψ→KSKS
- 2017
-
In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
-
Journal article (peer-reviewed)abstract
- Using a sample of 1.31 x 10(9) J/Psi events collected with the BESIII detector at the BEPCII collider, we study the decays of J/Psi -> KSKL and KSKS. The branching fraction of J/Psi -> KSKL is determined to be B(J/Psi -> KSKL) = (1.93 +/- 0.01 (stat) +/- 0.05 (syst)) x 10(-4), which significantly improves on previous measurements. No clear signal is observed for the J/Psi -> KSKS process, and the upper limit at the 95% confidence level for its branching fraction is determined to be B(J/Psi -> KSKS) < 1.4 x 10(-8), which improves on the previous searches by 2 orders in magnitude and reaches the order of the Einstein-Podolsky-Rosen expectation.
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6. |
- Ablikim, M., et al.
(author)
-
Evidence for e+e−→γηc(1S) at center-of-mass energies between 4.01 and 4.60 GeV
- 2017
-
In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:5
-
Journal article (peer-reviewed)abstract
- We present first evidence for the process e(+)e(-) -> gamma eta(c)(1S) at six center-of-mass energies between 4.01 and 4.60 GeV using data collected by the BESIII experiment operating at BEPCII. We measure the Born cross section at each energy using a combination of twelve eta(c)(1S) decay channels. We also combine all six energies under various assumptions for the energy-dependence of the cross section. If the process is assumed to proceed via the Y(4260), we measure a peak Born cross section sigma(peak)(e(+)e(-) -> gamma eta(c)(1S)) = 2.11 +/- 0.49 (stat.) +/- 0.36 (syst.) pb with a statistical significance of 4.2 sigma.
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7. |
- Ablikim, M., et al.
(author)
-
Improved measurements of X-cJ -> Sigma(+) (Sigma)over-bar(-) and Sigma(0)(Sigma)over-bar(0) decays
- 2018
-
In: Physical Review D. - : American Physical Society. - 2470-0010 .- 2470-0029. ; 97:5
-
Journal article (peer-reviewed)abstract
- Using a data sample of (448.1 +/- 2.9) x 10(6) psi (3686) events collected with the BESIII detector at the BEPCII collider, we present measurements of branching fractions for the decays X-cJ -> Sigma(+) (Sigma) over bar (-) and Sigma(0) (Sigma) over bar (0) The decays X-c1.2 -> Sigma(+) (Sigma) over bar (-) and Sigma (Sigma) over bar (0) are observed for the first time, and the branching fractions for X-c0 -> Sigma(+) (Sigma) over bar (-) and Sigma(0) (Sigma) over bar (0) decays are measured with improved precision. The branching fraction ratios between the charged and neutral modes are consistent with the prediction of isospin symmetry.
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8. |
- Ablikim, M., et al.
(author)
-
Measurement of branching fractions for psi(3686) -> gamma eta ', gamma eta, and gamma pi(0)
- 2017
-
In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 96:5
-
Journal article (peer-reviewed)abstract
- Using a data sample of 448 x 10(6) psi(3686) events collected with the BESIII detector operating at the BEPCII storage ring, the decays psi(3686) -> gamma eta and psi(3686) -> gamma pi(0) are observed with a statistical significance of 7.3 sigma and 6.7 sigma, respectively. The branching fractions are measured to be B(psi(3686) -> gamma eta) = (0.85 +/- 0.18 +/- 0.05) x 10(-6) and B(psi(3686) ->gamma pi(0)) = (0.95 +/- 0.16 +/- 0.05) x 10(-6). In addition, we measure the branching fraction of psi(3686) -> gamma eta' to be B(psi(3686) -> gamma eta') = (125.1 +/- 2.2 +/- 6.2)x10(-6), which represents an improvement of precision over previous results.
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9. |
- Ablikim, M., et al.
(author)
-
Measurement of the matrix elements for the decays eta' -> eta pi(+) pi(-) and eta' -> eta pi(0)pi(0)
- 2018
-
In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:1
-
Journal article (peer-reviewed)abstract
- Based on a sample of 1.31 x 10(9) J/psi events collected with the BESIII detector, the matrix elements for the decays eta' -> eta pi(+) pi(-) and eta' -> eta pi(0)pi(0) are determined using 351,016 eta' -> (eta -> gamma gamma)pi' pi(-) and 56,249 eta' -> (eta -> gamma gamma)pi(0) pi(0) events with background levels less than 1%. Two commonly used representations are used to describe the Dalitz plot density. We find that an assumption of a linear amplitude does not describe the data well. A small deviation of the obtained matrix elements between eta' -> eta pi(+) pi(-) and eta' -> eta pi(0)pi(0) is probably caused by the mass difference between charged and neutral pions or radiative corrections. No cusp structure in eta' -> eta pi(0)pi(0) is observed.
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10. |
- Ablikim, M., et al.
(author)
-
Measurements of the branching fractions for the semileptonic decays D-s(+) -> phi e(+)v(e), phi mu(+)v(mu), eta mu(+)v(mu) and eta 'mu(+)v(mu)
- 2018
-
In: Physical Review D. - : American Physical Society. - 2470-0010 .- 2470-0029. ; 97:1
-
Journal article (peer-reviewed)abstract
- By analyzing 482 pb(-1) of e(+) e(-) collision data collected at the center-of-mass energy root s = 4.009 GeV with the BESIII detector, we measure the branching fractions for the semi-leptonic decays D-s(+) -> phi e(+)v(e), phi mu(+)v(mu), eta mu(+)v(mu) and eta'mu(+)v(mu) to be B(D-s(+) -> phi e(+)v(e)) = (2.26 +/- 0.45 +/- 0.09)%, B(D-s(+) -> phi mu+v(mu)) = (1.94 +/- 0.53 +/- 0.09)%, B(D-s(+) -> eta mu(+)v(mu)) = (2.42 +/- 0.46 +/- 011)% and B(D-s(+) -> eta'mu(+)v(mu)) = (1.06 +/- 0.54 +/- 0.07)%, where the first and second uncertainties are statistical and systematic, respectively. The branching fractions for the three semi-muonic decays D-s(+) -> phi mu(+)v(mu), eta mu(+)v(mu) and eta'mu(+)v(mu) are determined for the first time and that of D-s(+) -> phi e(+)v(e) is consistent with the world average value within uncertainties.
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11. |
- Ablikim, M., et al.
(author)
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Observation of a(0)(0)(980)-f(0)(980) Mixing
- 2018
-
In: Physical Review Letters. - : AMER PHYSICAL SOC. - 0031-9007 .- 1079-7114. ; 121:2
-
Journal article (peer-reviewed)abstract
- We report the first observation of a(0)(0)(980)-f(0)(980) mixing in the decays of J/psi -> phi f(0)(980) -> phi a(0)(0)(980) -> phi eta pi(0) and chi(c1) -> a(0)(0)(980)pi(0) -> f(0)(980)pi(0)->pi(+)pi(-)pi(0), using data samples of 1.31 x 10(9) J/psi events and 4.48 x 10(8) psi (3686) events accumulated with the BESIII detector. The signals of f(0)(980) -> a(0)(0)(980) and a(0)(0)(980) -> f(0)(980) mixing are observed at levels of statistical significance of 7.4 sigma and 5.5 sigma, respectively. The corresponding branching fractions and mixing intensities are measured and the constraint regions on the coupling constants, g(a0K+K-) and g(f0K+K-), are estimated. The results improve the understanding of the nature of a(0)(0)(980) and f(0)(980).
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12. |
- Ablikim, M., et al.
(author)
-
Observation of χc2→η′η′ and χc0,2→ηη′
- 2017
-
In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
-
Journal article (peer-reviewed)abstract
- Using a sample of 448.1×106 ψ(3686) events collected with the BESIII detector in 2009 and 2012, we study the decays χc0,2→η′η′ and ηη′. The decays χc2→η′η′, χc0→ηη′ and χc2→ηη′ are observed for the first time with statistical significances of 9.6σ, 13.4σ and 7.5σ, respectively. The branching fractions are determined to be B(χc0→η′η′)=(2.19±0.03±0.14)×10−3, B(χc2→η′η′)=(4.76±0.56±0.38)×10−5, B(χc0→ηη′)=(8.92±0.84±0.65)×10−5 and B(χc2→ηη′)=(2.27±0.43±0.25)×10−5, where the first uncertainties are statistical and the second are systematic. The precision for the measurement of B(χc0→η′η′) is significantly improved compared to previous measurements. Based on the measured branching fractions, the role played by the doubly and singly Okubo-Zweig-Iizuka disconnected transition amplitudes for χc0,2 decays into pseudoscalar meson pairs can be clarified.
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13. |
- Ablikim, M., et al.
(author)
-
Search for the rare decays J/ψ→D0e+e−+c.c. and ψ(3686)→D0e+e−+c.c.
- 2017
-
In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
-
Journal article (peer-reviewed)abstract
- Using the data samples of (1310.6 +/- 7.2) x 10(6) J/psi events and (448.1 +/- 2.9) x 10(6) psi(3686) events collected with the BESIII detector, we search for the rare decays J/psi -> D(0)e(+) e(-) + c.c. and psi(3686) -> D(0)e(+) e(-) + c.c. No significant signals are observed and the corresponding upper limits on the branching fractions at the 90% confidence level are determined to be B(J/psi -> D(0)e(+) e(-) + c.c.) < 8.5 x 10(-8) and B(psi(3686) -> D(0)e(+) e(-) + c.c.) < 1.4 x 10(-7), respectively. Our limit on B(J/psi -> D(0)e(+) e(-) + c.c.) is more stringent by 2 orders of magnitude than the previous results, and B(psi(3686) -> D(0)e(+) e(-) + c.c.) is measured for the first time.
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14. |
- Ablikim, M., et al.
(author)
-
Search for ψ(3686)→γηc(η(1405))→γπ+π−π0
- 2017
-
In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
-
Journal article (peer-reviewed)abstract
- Using a sample of 448.1×106 ψ(3686) events collected with the BESIII detector, a search for the isospin violating decay ηc→π+π−π0 via ψ(3686)→γηc is presented. No signal is observed, and the upper limit on B(ψ(3686)→γηc)×B(ηc→π+π−π0) is determined to be 1.6×10−6 at the 90% confidence level. In addition, a search for η(1405)→f0(980)π0 in ψ(3686) radiative decays is performed. No signal is observed, and the branching fraction B(ψ(3686)→γη(1405))×B(η(1405)→f0(980)π0)×B(f0(980)→π+π−) is calculated to be less than 5.0×10−7 at the 90% confidence level.
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15. |
- Ablikim, M., et al.
(author)
-
Study of J/ψ and ψ(3686) decays to π+π−η′
- 2017
-
In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:11
-
Journal article (peer-reviewed)abstract
- Using the data samples of 1.31×109 J/ψ events and 4.48×108 ψ(3686) events collected with the BESIII detector, partial wave analyses on the decays J/ψ and ψ(3686)→π+π−η′ are performed with a relativistic covariant tensor amplitude approach. The dominant contribution is found to be J/ψ and ψ(3686) decays to ρη′. In the J/ψ decay, the branching fraction B(J/ψ→ρη′) is determined to be (7.90±0.19(stat)±0.49(sys))×10−5. Two solutions are found in the ψ(3686) decay, and the corresponding branching fraction B(ψ(3686)→ρη′) is (1.02±0.11(stat)±0.24(sys))×10−5 for the case of destructive interference, and (5.69±1.28(stat)±2.36(sys))×10−6 for constructive interference. As a consequence, the ratios of branching fractions between ψ(3686) and J/ψ decays to ρη′ are calculated to be (12.9±1.4(stat)±3.1(sys))% and (7.2±1.6(stat)±3.0(sys))%, respectively. We also determine the inclusive branching fractions of J/ψ and ψ(3686) decays to π+π−η′ to be (1.36±0.02(stat)±0.08(sys))×10−4 and (1.51±0.14(stat)±0.23(sys))×10−5, respectively
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16. |
- de las Fuentes, Lisa, et al.
(author)
-
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
- 2021
-
In: Molecular Psychiatry. - : Springer Nature. - 1359-4184 .- 1476-5578. ; 26:6, s. 2111-2125
-
Journal article (peer-reviewed)abstract
- Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses accounting for gene-educational attainment interactions using two variables, “Some College” (yes/no) and “Graduated College” (yes/no). Interactions were evaluated using both a 1 degree of freedom (DF) interaction term and a 2DF joint test of genetic and interaction effects. Analyses were performed for systolic BP, diastolic BP, mean arterial pressure, and pulse pressure. We pursued genome-wide interrogation in Stage 1 studies (N = 117 438) and follow-up on promising variants in Stage 2 studies (N = 293 787) in five ancestry groups. Through combined meta-analyses of Stages 1 and 2, we identified 84 known and 18 novel BP loci at genome-wide significance level (P < 5 × 10-8). Two novel loci were identified based on the 1DF test of interaction with educational attainment, while the remaining 16 loci were identified through the 2DF joint test of genetic and interaction effects. Ten novel loci were identified in individuals of African ancestry. Several novel loci show strong biological plausibility since they involve physiologic systems implicated in BP regulation. They include genes involved in the central nervous system-adrenal signaling axis (ZDHHC17, CADPS, PIK3C2G), vascular structure and function (GNB3, CDON), and renal function (HAS2 and HAS2-AS1, SLIT3). Collectively, these findings suggest a role of educational attainment or SES in further dissection of the genetic architecture of BP.
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17. |
- Feitosa, Mary F., et al.
(author)
-
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
- 2018
-
In: PLOS ONE. - : Public library science. - 1932-6203. ; 13:6
-
Journal article (peer-reviewed)abstract
- Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcohol consumption interaction for BP might identify additional BP loci and contribute to the understanding of alcohol-related BP regulation. We conducted a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions. In Stage 1, genome-wide discovery meta-analyses in approximate to 131 K individuals across several ancestry groups yielded 3,514 SNVs (245 loci) with suggestive evidence of association (P <1.0 x 10(-5)). In Stage 2, these SNVs were tested for independent external replication in individuals across multiple ancestries. We identified and replicated (at Bonferroni correction threshold) five novel BP loci (380 SNVs in 21 genes) and 49 previously reported BP loci (2,159 SNVs in 109 genes) in European ancestry, and in multi-ancestry meta-analyses (P < 5.0 x 10(-8)). For African ancestry samples, we detected 18 potentially novel BP loci (P< 5.0 x 10(-8)) in Stage 1 that warrant further replication. Additionally, correlated meta-analysis identified eight novel BP loci (11 genes). Several genes in these loci (e.g., PINX1, GATA4, BLK, FTO and GABBR2 have been previously reported to be associated with alcohol consumption. These findings provide insights into the role of alcohol consumption in the genetic architecture of hypertension.
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18. |
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19. |
- Wang, Zhaoming, et al.
(author)
-
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
- 2014
-
In: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 23:24, s. 6616-6633
-
Journal article (peer-reviewed)abstract
- Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play a role in apoptosis. To investigate further the genetic architecture of common susceptibility alleles in this region, we conducted an agnostic subset-based meta-analysis (association analysis based on subsets) across six distinct cancers in 34 248 cases and 45 036 controls. Based on sequential conditional analysis, we identified as many as six independent risk loci marked by common single-nucleotide polymorphisms: five in the TERT gene (Region 1: rs7726159, P = 2.10 × 10(-39); Region 3: rs2853677, P = 3.30 × 10(-36) and PConditional = 2.36 × 10(-8); Region 4: rs2736098, P = 3.87 × 10(-12) and PConditional = 5.19 × 10(-6), Region 5: rs13172201, P = 0.041 and PConditional = 2.04 × 10(-6); and Region 6: rs10069690, P = 7.49 × 10(-15) and PConditional = 5.35 × 10(-7)) and one in the neighboring CLPTM1L gene (Region 2: rs451360; P = 1.90 × 10(-18) and PConditional = 7.06 × 10(-16)). Between three and five cancers mapped to each independent locus with both risk-enhancing and protective effects. Allele-specific effects on DNA methylation were seen for a subset of risk loci, indicating that methylation and subsequent effects on gene expression may contribute to the biology of risk variants on 5p15.33. Our results provide strong support for extensive pleiotropy across this region of 5p15.33, to an extent not previously observed in other cancer susceptibility loci.
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20. |
- Ablikim, M., et al.
(author)
-
Amplitude analysis of D0 → K -π+π+π-
- 2017
-
In: Physical Review D. - 2470-0010 .- 2470-0029. ; 95:7
-
Journal article (peer-reviewed)abstract
- We present an amplitude analysis of the decay D0 → K -π+π+π- based on a data sample of 2.93 fb−1 acquired by the BESIII detector at the ψ(3770) resonance. With a nearly background free sample of about 16000 events, we investigate the substructure of the decay and determine the relative fractions and the phases among the different intermediate processes. Our amplitude model includes the two-body decays D0 → ¯K*0ρ0, D0 → K−a+1(1260) and D0 → K−1(1270)π+, the three-body decays D0 →¯K*0π+π− and D0 → K−π+ρ0, as well as the four-body nonresonant decay D0 → K−π+π+π−. The dominant intermediate process is D0 → K−a+1(1260), accounting for a fit fraction of 54.6%.
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21. |
- Ablikim, M., et al.
(author)
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Amplitude analysis of the D+ -> K-S(0)pi + (0)(pi) Dalitz plot
- 2014
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:5, s. 052001-
-
Journal article (peer-reviewed)abstract
- We perform an analysis of the D+ -> K-S(0)pi + (0)(pi) Dalitz plot using a data set of 2.92 fb(-1) of e(+) e(-) collisions at the (3770) mass accumulated by the BESIII experiment, in which 166694 candidate events are selected with a background of 15.1%. The Dalitz plot is found to be well represented by a combination of six quasitwo- body decay channels [k(SP)(0)(+) (1450)(+,) ] plus a small nonresonant component. Using the fit fractions from this analysis, partial branching ratios are updated with higher precision than previous measurements.
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22. |
- Ablikim, M., et al.
(author)
-
Amplitude analysis of the KSKS system produced in radiative J /psi decays
- 2018
-
In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 98:7
-
Journal article (peer-reviewed)abstract
- An amplitude analysis of the KSKS system produced in radiative J/psi decays is performed using the (1310.6 +/- 7.0) x 10(6) nip decays collected by the BESIII detector. Two approaches are presented. A mass-dependent analysis is performed by parametrizing the KSKS invariant mass spectrum as a sum of Breit-aligner line shapes. Additionally, a mass-independent analysis is performed to extract a piecewise function that describes the dynamics of the KSKS system while making minimal assumptions about the properties and number of poles in the amplitude. The dominant amplitudes in the mass-dependent analysis include the f(0)(1710), f(0)(2200), and f(2)'(1525). The mass-independent results, which are made available as input for further studies, are consistent with those of the mass-dependent analysis and are useful for a systematic study of hadronic interactions. The branching fraction of radiative J/psi decays to KSKS is measured to be (8.1 +/- 0.4) x 10(-4), where the uncertainty is systematic and the statistical uncertainty is negligible.
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23. |
- Ablikim, M., et al.
(author)
-
Amplitude analysis of the pi(0)pi(0) system produced in radiative J/psi decays
- 2015
-
In: Physical Review D. - 1550-7998 .- 1550-2368. ; 92:5
-
Journal article (peer-reviewed)abstract
- An amplitude analysis of the pi(0)pi(0) system produced in radiative J/psi decays is presented. In particular, a piecewise function that describes the dynamics of the pi(0)pi(0) system is determined as a function of M pi(0)pi(0) from an analysis of the (1.311 +/- 0.011) x 10(9) J/psi decays collected by the BESIII detector. The goal of this analysis is to provide a description of the scalar and tensor components of the pi(0)pi(0) system while making minimal assumptions about the properties or number of poles in the amplitude. Such a model-independent description allows one to integrate these results with other related results from complementary reactions in the development of phenomenological models, which can then be used to directly fit experimental data to obtain parameters of interest. The branching fraction of J/psi -> pi(0)pi(0) is determined to be (1.15 +/- 0.05) x 10(-3), where the uncertainty is systematic only and the statistical uncertainty is negligible.
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24. |
- Ablikim, M., et al.
(author)
-
Amplitude analysis of the π$^0$π$^0$ system produced in radiative J/ψ decays
- 2016
-
In: PHYSICAL REVIEW D. - 2470-0010. ; 93:3
-
Journal article (peer-reviewed)abstract
- An amplitude analysis of the π0π0 system produced in radiative J/ψ decays is presented. In particular, a piecewise function that describes the dynamics of the π0π0 system is determined as a function of Mπ0π0 from an analysis of the (1.311±0.011)×109 J/ψ decays collected by the BESIII detector. The goal of this analysis is to provide a description of the scalar and tensor components of the π0π0 system while making minimal assumptions about the properties or number of poles in the amplitude. Such a model-independent description allows one to integrate these results with other related results from complementary reactions in the development of phenomenological models, which can then be used to directly fit experimental data to obtain parameters of interest. The branching fraction of J/ψ→γπ0π0 is determined to be (1.15±0.05)×10-3, where the uncertainty is systematic only and the statistical uncertainty is negligible.
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25. |
- Ablikim, M., et al.
(author)
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An improved limit for Gamma(ee) of X(3872) and Gamma(ee) measurement of psi(3686)
- 2015
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In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 749, s. 414-420
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Journal article (peer-reviewed)abstract
- Using the data sets taken at center-of-mass energies above 4 GeV by the BESIII detector at the BEPCII storage ring, we search for the reaction e(+)e(-) -> gamma(ISR) X(3872) -> gamma(ISR)pi(+)pi(-) J/psi via the Initial State Radiation technique. The production of a resonance with quantum numbers J(PC) = 1(++) such as the X(3872) via single photon e(+)e(-) annihilation is forbidden, but is allowed by a next-to-leading order box diagram. We do not observe a significant signal of X(3872), and therefore give an upper limit for the electronic width times the branching fraction Gamma B-X(3872)(ee)(X(3872) -> pi(+)pi(-) J/psi) < 0.13 eVat the 90% confidence level. This measurement improves upon existing limits by a factor of 46. Using the same final state, we also measure the electronic width of the psi(3686) to be Gamma(psi)(ee)(3686) ee = 2213 +/- 18(stat) +/- 99(sys) eV.
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