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- Thomas, HS, et al.
(author)
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- 2019
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swepub:Mat__t
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- Drake, TM, et al.
(author)
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Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study
- 2020
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In: BMJ global health. - : BMJ. - 2059-7908. ; 5:12
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Journal article (peer-reviewed)abstract
- Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings.MethodsA multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI).ResultsOf 1159 children across 181 hospitals in 51 countries, 523 (45·1%) children were from high HDI, 397 (34·2%) from middle HDI and 239 (20·6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12·8% (51/397) in middle HDI and 24·7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI.ConclusionThe odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.
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- Daum, M., et al.
(author)
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Actions seen through the babies' eyes : A dissociation between looking and predictive gaze
- 2012
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In: Frontiers in Psychology. - : Frontiers Media SA. - 1664-1078. ; 3
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Journal article (peer-reviewed)abstract
- In this study, we explored the relation of two different measures used to investigate infants' expectations about goal-directed actions. In previous studies, expectations about action outcomes have been either measured after the action has been terminated, that is posthoc (e.g., via looking time) or during the action is being performed, that is online (e.g., via predictive gaze). Here, we directly compared both types of measures. Experiment 1 demonstrated a dissociation between looking time and predictive gaze for 9-month-olds. Looking time reflected identity-related expectations whereas predictive gaze did not. If at all, predictive gaze reflected location-related expectations. Experiment 2, including a wider age range, showed that the two measures remain dissociated over the first 3 years of life. It is only after the third birthday that the dissociation turns into an association, with both measures then reflecting identity-related expectations. We discuss these findings in terms of an early dissociation between two mechanisms for action expectation. We speculate that while post-hoc measures primarily tap ventral mechanisms for processing identity-related information (at least at a younger age), online measures primarily tap dorsal mechanisms for processing location-related information.
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