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1.	Bousquet, J, et al. (author) Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015 2016 In: Allergy. - : Wiley. - 1398-9995 .- 0105-4538. ; 71:11, s. 1513-1525 Journal article (peer-reviewed)
2.	Anto, JM, et al. (author) Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes 2017 In: The Journal of allergy and clinical immunology. - : Elsevier BV. - 1097-6825 .- 0091-6749. ; 139:2, s. 388-399 Journal article (peer-reviewed)
3.	Barlind, Jonas G, et al. (author) Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687) 2012 In: Journal of Medicinal Chemistry. - : American Chemical Society (ACS). - 0022-2623 .- 1520-4804. ; 55:23, s. 10610-10629 Journal article (peer-reviewed)abstract A new series of pyrazinecarboxamide DGAT1 inhibitors was designed to address the need for a candidate drug with good potency, selectivity, and physical and DMPK properties combined with a low predicted dose in man. Rational design and optimization of this series led to the discovery of compound 30 (AZD7687), which met the project objectives for potency, selectivity, in particular over ACAT1, solubility, and preclinical PK profiles. This compound showed the anticipated excellent pharmacokinetic properties in human volunteers.
4.	Eccleshall, Sarah V., et al. (author) Constraining the chronology of Pleistocene glaciations on Svalbard: Kapp Ekholm re-visited 2016 In: Boreas. - : Wiley. - 0300-9483 .- 1502-3885. ; 45:4, s. 790-803 Journal article (peer-reviewed)abstract Â© 2016 Collegium Boreas. Published by John Wiley & Sons LtdThe Kapp Ekholm site, in central Spitsbergen, shows alternating units of glaciomarine sandy silt and diamicton representing three glacial cycles and is key in reconstructing the Late Pleistocene glacial history of Svalbard. Part of the site is reinvestigated here by focusing on re-dating two units (B and F) interpreted as interglacial/interstadial glaciomarine deposits, in order to constrain the controversial chronology. A combination of Optical Stimulated Luminescence (OSL) on quartz, infrared stimulated luminescence with a 50ÂÂ°C readout temperature (IRSL50) and post infrared-infrared stimulated luminescence (pIR), both on feldspar, was applied. While Formation B was beyond the dateable range of OSL, IRSL50 and pIR ages lead to the conclusion that this unit represents the Last Interglacial, Marine Isotope Stage (MIS) 5e, and the underlying diamicton the MIS 6 glacial. Formation F yielded ages implying that the formation represents the MIS 5a interstadial and the underlying diamicton is interpreted to represent the MIS 5b stadial. This agrees with conclusions drawn concerning the Pleistocene glaciations elsewhere on Svalbard.
5.	Skrindo, I, et al. (author) The MeDALL-chip, a new diagnostic tool for allergic disease 2014 In: ALLERGY. - 0105-4538. ; 69, s. 8-9 Conference paper (other academic/artistic)
6.	Skrindo, I, et al. (author) The use of the MeDALL-chip to assess IgE sensitization: a new diagnostic tool for allergic disease? 2015 In: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. - : Wiley. - 1399-3038. ; 26:3, s. 239-246 Journal article (peer-reviewed)
7.	Xu, CJ, et al. (author) DNA methylation in childhood asthma: an epigenome-wide meta-analysis 2018 In: The Lancet. Respiratory medicine. - 2213-2619. ; 6:5, s. 379-388 Journal article (peer-reviewed)
8.	Xu, CJ, et al. (author) Shared DNA methylation signatures in childhood allergy: The MeDALL study 2021 In: The Journal of allergy and clinical immunology. - : Elsevier BV. - 1097-6825 .- 0091-6749. ; 147:3, s. 1031-1040 Journal article (peer-reviewed)

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Type of publication: journal article (7); conference paper (1)

Type of content: peer-reviewed (7); other academic/artistic (1)

Author/Editor: Bousquet, J (6); Melen, E (6); Carlsen, KH (6); Anto, JM (5); Mowinckel, P (5); Carlsen, KCL (5); show more...; Sunyer, J (4); Wright, J (4); Valenta, R (4); Koppelman, GH (4); Kogevinas, M (4); Gehring, U (4); Forastiere, F (3); Auffray, C (3); Kull, I (3); Nawijn, MC (3); Ballereau, S (3); Garcia-Aymerich, J (3); Guerra, S (3); Lemonnier, N (3); Wickman, M (3); Brunekreef, B (3); Bergstrom, A (3); Li, Y. (2); Heinrich, J. (2); Bachert, C (2); Postma, DS (2); Demoly, P. (2); Pin, I. (2); Soderhall, C (2); Alenius, H (2); Wijmenga, C (2); Maier, D (2); Akdis, C (2); Akdis, M (2); Pinart, M (2); Saeys, Y (2); Benet, M (2); Keil, T (2); Bustamante, M (2); Gruzieva, O (2); Westman, M (2); Standl, M (2); Bindslev-Jensen, C (2); Zuberbier, T (2); Bedbrook, A (2); Fyhrquist, N (2); Kiss, R (2); Ballester, F (2); Basagana, X. (2); show less...

University: Karolinska Institutet (6); University of Gothenburg (1); Uppsala University (1); Stockholm University (1)

Language: English (8)

Research subject (UKÄ/SCB): Natural sciences (1)

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