| 1. |
- Thomas, HS, et al.
(author)
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- 2019
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swepub:Mat__t
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| 2. |
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| 3. |
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| 4. |
- Ferreira, Mjv, et al.
(author)
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Poster Session 3 : Tuesday 5 May 2015, 08
- 2015
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In: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 16 Suppl 1
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Journal article (peer-reviewed)
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| 5. |
- Medema, M. H., et al.
(author)
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Minimum Information about a Biosynthetic Gene cluster
- 2015
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In: Nature Chemical Biology. - : Springer Science and Business Media LLC. - 1552-4450 .- 1552-4469. ; 11:9, s. 625-631
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Research review (peer-reviewed)abstract
- A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.
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| 8. |
- Ademuyiwa, Adesoji O., et al.
(author)
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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
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In: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
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Journal article (peer-reviewed)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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| 9. |
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| 10. |
- Hakim, M. A., et al.
(author)
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Dilution of the magnetic moment of Fe by Cr for Fe73.5-xCrxCu1Nb3Si13.5B9 and the field-cooled and zero-field-cooled behavior for higher Cr content
- 2008
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In: Journal of the Korean Physical Society. - 0374-4884 .- 1976-8524. ; 53:2, s. 766-771
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Journal article (peer-reviewed)abstract
- The temperature and the field dependences of the magnetization have been measured for Fe73.5-xCrxCu1Nb3Si13.5B9 (0 < ;= x < ;= 17.5) prepared by using a melt spin technique. The temperature dependence of the magnetization in the range of 5 to 300 K with an applied field of I Tesla for all the compositions follows the relaxation M(T) = M-0(1 - BT3/2 - CT5/2), which is indicative of the presence of a spin wave excitation. The saturation magnetizations at 5 and 300 K decrease linearly with Cr concentration for the entire composition range, which indicates that a simple dilution of the Fe moment takes place due to Cr substitution. The field-cooled (FC) and the zero-field-cooled (ZFC) magnetizations measured with an applied field of 1 Oe show divergences for x = 10, 12.5, 15 and 17.5, which may be attributed to the magnetic hardening at low temperatures.
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| 11. |
- Injamul Hoq, Mohammad, et al.
(author)
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Trends in the Prevalence of Hypertension and Type 2 Diabetes in Bangladesh (2010-2020): A Systematic Review and Meta-Analysis
- 2023
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In: Current Diabetes Reviews. - : Bentham Science Publishers Ltd.. - 1573-3998. ; 19:6
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Journal article (peer-reviewed)abstract
- Background The prevalence of cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM) has increased in Bangladesh. This paper has reviewed published studies on hypertension and T2DM from 2010 to 2020 in Bangladesh and conducted a meta-analysis. Methods The PubMed database was used for systematic search. Hypertension and T2DM were considered for measuring pooled prevalence by meta-analysis. The random-effects model was used to calculate the pooled prevalence of hypertension (n = 30) and T2DM (n = 21) in relevant studies. The quality of the reviewed studies was determined by sampling strategy, sample size, and outcome assessment. The meta-analysis protocol was registered at PROSPERO (CRD42020206315). Results The pooled hypertension and T2DM prevalence was 21.6% (95% CI: 18.8%-24.4%) and 13.6% (95% CI: 10.8%-16.5%), respectively. Females were more hypertensive than males (M vs. F: 18.6% vs. 24.8%), and T2DM was higher in females (M vs. F: 12.4% vs. 13.3%). Urban dwellers were more hypertensive and diabetic than rural people (urban vs. rural: 28.5% vs. 20.3% and 18.8% vs. 14.2%, respectively). An 8% increase in the prevalence of hypertension and T2DM became more than double compared to the 1995-2010 period. Conclusion Future research should focus on the underlying factors that increase the prevalence of these diseases and prevention strategies to reduce the trend of increasing prevalence.
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| 15. |
- Jiang, Mingkai, et al.
(author)
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The fate of carbon in a mature forest under carbon dioxide enrichment
- 2020
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In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 580:7802, s. 227-231
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Journal article (peer-reviewed)abstract
- Atmospheric carbon dioxide enrichment (eCO2) can enhance plant carbon uptake and growth1–5, thereby providing an important negative feedback to climate change by slowing the rate of increase of the atmospheric CO2 concentration6. Although evidence gathered from young aggrading forests has generally indicated a strong CO2 fertilization effect on biomass growth3–5, it is unclear whether mature forests respond to eCO2 in a similar way. In mature trees and forest stands7–10, photosynthetic uptake has been found to increase under eCO2 without any apparent accompanying growth response, leaving the fate of additional carbon fixed under eCO2 unclear4,5,7–11. Here using data from the first ecosystem-scale Free-Air CO2 Enrichment (FACE) experiment in a mature forest, we constructed a comprehensive ecosystem carbon budget to track the fate of carbon as the forest responded to four years of eCO2 exposure. We show that, although the eCO2 treatment of +150 parts per million (+38 per cent) above ambient levels induced a 12 per cent (+247 grams of carbon per square metre per year) increase in carbon uptake through gross primary production, this additional carbon uptake did not lead to increased carbon sequestration at the ecosystem level. Instead, the majority of the extra carbon was emitted back into the atmosphere via several respiratory fluxes, with increased soil respiration alone accounting for half of the total uptake surplus. Our results call into question the predominant thinking that the capacity of forests to act as carbon sinks will be generally enhanced under eCO2, and challenge the efficacy of climate mitigation strategies that rely on ubiquitous CO2 fertilization as a driver of increased carbon sinks in global forests.
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| 16. |
- Mahmud, Shadman, et al.
(author)
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Bioethanol and biodiesel blended fuels : Feasibility analysis of biofuel feedstocks in Bangladesh
- 2022
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In: Energy Reports. - Oxford, United Kingdom : John Wiley & Sons. - 2352-4847. ; 8, s. 1741-1756
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Research review (peer-reviewed)abstract
- In 2019–2020, Bangladesh imported 5.2 million metric tonnes of petroleum products, worth 2.5 billion USD, and 50% of the imports were consumed by the transportation sector. Having limited natural oil reserves and being heavily dependent on oil imports, the country is vulnerable to shocks in the international oil market, which can jeopardize its consistent economic growth. The Government announced a 5% blending of bioethanol with gasoline in 2017, with broken rice, maize, and molasses as the feedstocks, but sourcing biofuel from food crops can hamper the country’s food security. This study explores second and third generation feedstocks e.g., organic plants, seeds, agricultural residues, and waste animal fat or skin that can be collected and processed for the extraction of biofuels. Technical potential of biofuel from the feedstocks is analysed which shows that Bangladesh has a potential to extract 44.4 million metric tonnes of bioethanol in a year from agricultural residues with rice residue having the highest potential (71%). Ground nut and rubber seeds can be major feedstocks for biodiesel production having a potential of 61,000 and 42,000 metric tonnes per year, respectively. Waste chicken skin can be another promising feedstock for the extraction of biodiesel. Biofuels extracted from these non-edible feedstocks and blended with existing transport fuels can lessen Bangladesh’s import bills through a sustainable, environmentally friendly manner.
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| 17. |
- Raihan Uddin, M., et al.
(author)
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Energy analysis of a solar driven vaccine refrigerator using environment-friendly refrigerants for off-grid locations
- 2021
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In: Energy Conversion and Management. - : Elsevier Ltd. - 2590-1745. ; 11
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Journal article (peer-reviewed)abstract
- In many remote localities, one of the underlying reasons for not receiving life-saving vaccines is the lack of electricity to store the vaccines in the required refrigerated conditions. Solar Photovoltaic (PV) refrigerators have been considered as a viable and green solution to store the vaccines in remote localities having no access to electricity. In this paper, a detailed methodology has been presented for the performance evaluation of a solar PV powered vaccine refrigerator for remote locations. Thermal modelling with hourly cooling load calculations and refrigeration cycle simulations were carried out. The performance parameters for three environment-friendly refrigerants: R152a, R1234yf, and R1234ze(E) has been compared against the commonly used R134a for two remote, off-grid locations in Bangladesh and South Sudan. The energy systems comprising of solar PV panels and batteries to run the refrigerator were modelled in HOMER software for techno-economic optimizations. For both the locations, R152a was found to be the best performing refrigerant exhibiting higher COP (2%−5.29%) as compared to the other refrigerants throughout the year, while R1234ze(E) exhibited COPs on par with R134a, and R1234yf had the least performance. Techno-economic analysis showed an energy system providing electricity to the refrigerator with R152a also had lower levelized cost of electricity (0.48%−2.54%) than the systems having other refrigerants in these locations.
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| 18. |
- Saba, Luca, et al.
(author)
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Carotid plaque-RADS : a novel stroke risk classification system
- 2024
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In: JACC Cardiovascular Imaging. - : Elsevier. - 1936-878X .- 1876-7591. ; 17:1, s. 62-75
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Journal article (peer-reviewed)abstract
- Background: Carotid artery atherosclerosis is highly prevalent in the general population and is a well-established risk factor for acute ischemic stroke. Although the morphological characteristics of vulnerable plaques are well recognized, there is a lack of consensus in reporting and interpreting carotid plaque features.Objectives: The aim of this document is to establish a consistent and comprehensive approach for imaging and reporting carotid plaque by introducing the Plaque–Reporting and Data System (RADS) score.Methods: A panel of experts recognized the necessity to develop a classification system for carotid plaque and its defining characteristics. Using a multimodality analysis approach, the Plaque-RADS categories were established through consensus, drawing on existing published reports.Results: The authors present a universal classification that is applicable to both researchers and clinicians. The Plaque-RADS score offers a morphological assessment in addition to the prevailing quantitative parameter of “stenosis.” The Plaque-RADS score spans from grade 1 (indicating complete absence of plaque) to grade 4 (representing complicated plaque). Accompanying visual examples are included to facilitate a clear understanding of the Plaque-RADS categories.Conclusions: Plaque-RADS is a standardized and reliable system of reporting carotid plaque composition and morphology via different imaging modalities, such as ultrasound, computed tomography, and magnetic resonance imaging. This scoring system has the potential to help in the precise identification of patients who may benefit from exclusive medical intervention and those who require alternative treatments, thereby enhancing patient care. A standardized lexicon and structured reporting promise to enhance communication between radiologists, referring clinicians, and scientists.
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| 19. |
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| 20. |
- Begum, Ruhena, et al.
(author)
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Heavy metal contamination in retailed food in Bangladesh : a dietary public health risk assessment
- 2023
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In: Frontiers in Sustainable Food Systems. - : Frontiers Media S.A.. - 2571-581X. ; 7
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Journal article (peer-reviewed)abstract
- IntroductionContamination with heavy and toxic metals along the food value chain is a public health concern in Bangladesh. MethodsIn this study, 608 fish and chicken samples from traditional and modern retail outlets in urban, peri-urban, and rural areas were collected and analyzed for chromium (Cr), cadmium (Cd), and lead (Pb) contamination, using atomic absorption spectrometry method. The daily intake, target hazard quotient and the target carcinogenic risk (for lead only) as a result of fish and chicken consumption was calculated based on mean results, and by Monte Carlo simulation in @Risk with 100,000 iterations (quantitative risk assessment). ResultsCr and Cd were detected in 80-86% of both chicken meat and fish samples, while Pb positivity found in chicken meat and fish was 54.9 and 23.3%, respectively. The mean concentration (+/- SD) of Cr, Cd, and Pb in chicken meat were 0.66 +/- 0.93, 0.02 +/- 0.03, and 0.09 +/- 0.10 mg/kg, respectively; and in fish were 0.49 +/- 0.62, 0.02 +/- 0.03, and 0.06 +/- 0.09 mg/kg, respectively. The estimated daily intakes of Cr, Cd, and Pb from chicken and fish were lower than the maximum tolerable daily intake in all studied areas. In addition, the target carcinogenic risk for Pb in chicken was lower than the negligible range, which indicated the risk of cancer due to exposure to Pb through chicken meat and fish consumption was very low. DiscussionThe present study concludes that consumption of chicken meat and fish in Bangladesh, currently at very low levels, is unlikely to constitute a major health risk for humans in respect to these metals. However, continuous market surveillance for heavy metals in food stuff is recommended, especially since consumers may increase their meat intake.
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| 21. |
- Bile, Ahmed S., et al.
(author)
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Rethinking (local) integration: domains of integration and their durability in Kismayo and Garowe, Somalia
- 2024
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In: Frontiers in Human Dynamics. - : Frontiers Media S.A.. - 2673-2726. ; 5
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Journal article (peer-reviewed)abstract
- Amidst the ever-expanding debates in various academic and policy fields around migrant and refugee integration and local integration, we bring these two concepts in conversation with one another. Until very recently, theories of integration have had a state-centric focus in the Global North. This article expands and complicates this literature to focus on displaced Somalis within Somalia and its borderlands living in the cities of Kismayo and Garowe using mixed qualitative and quantitative methods in five displacement settlements. Toward this end, we use the often- engaged term “domains of integration” to frame integration. In our conceptualization, however, we incorporate the concept of “local integration” as a durable solution. In brief, we see the domains of integration as a productive concept in the Somali context. However, in Somalia, where clans are interwoven into the state, which lacks resources and power, clan affiliation represents social connections domains, yet also influences the state's role in the foundational domain of rights and citizenship and makers and means (employment, housing, education, health). International donors and NGOs, as well as international capitalist urban expansion also have a large role in these processes. As such, we argue that the ten domains of integration (discussed in detail below) intersect and blur to an even greater extent than in European and North American contexts, particularly around crucial issues such as housing, land, and property; a key factor in people's decisions to remain or leave.
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| 22. |
- Di Falco, S., et al.
(author)
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Estimating the Impact of Climate Change on Agriculture in Low-Income Countries: Household Level Evidence from the Nile Basin, Ethiopia
- 2012
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In: Environmental & Resource Economics. - : Springer Science and Business Media LLC. - 0924-6460 .- 1573-1502. ; 52:4, s. 457-478
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Journal article (peer-reviewed)abstract
- This paper presents an empirical analysis of the impact of climate change on agriculture in a typical developing country. The economic implications of climate change are estimated by using both a farm productivity and a Ricardian framework. Data are drawn from about 1,000 farms producing cereal crops in the Nile Basin of Ethiopia. The thin plate spline method of spatial interpolation was used to predict household specific rainfall and temperature values using meteorological station data collected for 30 years across the regions. We found that climate change adaptation has a significant impact on both farm productivity and farm net revenues. We complement the analysis by providing an estimation of the determinants of adaptation. Extension services (both formal and farmer to farmer), as well as access to credit and information on future climate changes are key drivers of adaptation.
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| 23. |
- Elahe, M. F., et al.
(author)
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Factors Impacting Short-Term Load Forecasting of Charging Station to Electric Vehicle
- 2023
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In: Electronics. - : MDPI. - 2079-9292. ; 12:1
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Journal article (peer-reviewed)abstract
- The rapid growth of electric vehicles (EVs) is likely to endanger the current power system. Forecasting the demand for charging stations is one of the critical issues while mitigating challenges caused by the increased penetration of EVs. Uncovering load-affecting features of the charging station can be beneficial for improving forecasting accuracy. Existing studies mostly forecast electricity demand of charging stations based on load profiling. It is difficult for public EV charging stations to obtain features for load profiling. This paper examines the power demand of two workplace charging stations to address the above-mentioned issue. Eight different types of load-affecting features are discussed in this study without compromising user privacy. We found that the workplace EV charging station exhibits opposite characteristics to the public EV charging station for some factors. Later, the features are used to design the forecasting model. The average accuracy improvement with these features is 42.73% in terms of RMSE. Moreover, the experiments found that summer days are more predictable than winter days. Finally, a state-of-the-art interpretable machine learning technique has been used to identify top contributing features. As the study is conducted on a publicly available dataset and analyzes the root cause of demand change, it can be used as baseline for future research.
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| 24. |
- Karlsborn, Tony, et al.
(author)
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Elongator, a conserved complex required for wobble uridine modifications in Eukaryotes
- 2014
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In: RNA Biology. - : Taylor & Francis. - 1547-6286 .- 1555-8584. ; 11:12, s. 1519-1528
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Journal article (peer-reviewed)abstract
- Elongator is a 6 subunit protein complex highly conserved in eukaryotes. The role of this complex has been controversial as the pleiotropic phenotypes of Elongator mutants have implicated the complex in several cellular processes. However, in yeast there is convincing evidence that the primary and probably only role of this complex is in formation of the 5-methoxycarbonylmethyl (mcm(5)) and 5-carbamoylmethyl (ncm(5)) side chains on uridines at wobble position in tRNA. In this review we summarize the cellular processes that have been linked to the Elongator complex and discuss its role in tRNA modification and regulation of translation. We also describe additional gene products essential for formation of ncm(5) and mcm(5) side chains at U-34 and their influence on Elongator activity.
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| 25. |
- Karlsborn, Tony, 1987-, et al.
(author)
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Loss of ncm5 and mcm5 wobble uridine side chains results in an altered metabolic profile
- 2016
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In: Metabolomics. - : Springer. - 1573-3882 .- 1573-3890. ; 12:12
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Journal article (peer-reviewed)abstract
- Introduction: The Elongator complex, comprising six subunits (Elp1p-Elp6p), is required for formation of 5-carbamoylmethyl (ncm(5)) and 5-methoxycarbonylmethyl (mcm(5)) side chains on wobble uridines in 11 out of 42 tRNA species in Saccharomyces cerevisiae. Loss of these side chains reduces the efficiency of tRNA decoding during translation, resulting in pleiotropic phenotypes. Overexpression of hypomodified tRNA(s2UUU)(Lys); tRNA(s2UUG)(Gln) and tRNA(s2UUC)(Glu), which in wild-type strains are modified with mcm(5)s(2)U, partially suppress phenotypes of an elp3 Delta strain. Objectives: To identify metabolic alterations in an elp3 Delta strain and elucidate whether these metabolic alterations are suppressed by overexpression of hypomodified tRNA(s2UUU)(Lys); tRNA(s2UUG)(Gln) and tRNA(s2UUC)(Glu). Method: Metabolic profiles were obtained using untargeted GC-TOF-MS of a temperature-sensitive elp3 Delta strain carrying either an empty low-copy vector, an empty high-copy vector, a low-copy vector harboring the wild-type ELP3 gene, or a high-copy vector overexpressing tRNA(s2UUU)(Lys); tRNA(s2UUG)(Gln) and tRNA(s2UUC)(Glu). The temperature sensitive elp3 Delta strain derivatives were cultivated at permissive (30 degrees C) or semi-permissive (34 degrees C) growth conditions. Results: Culturing an elp3 Delta strain at 30 or 34 degrees C resulted in altered metabolism of 36 and 46 %, respectively, of all metabolites detected when compared to an elp3D strain carrying the wild-type ELP3 gene. Overexpression of hypomodified tRNA(s2UUU)(Lys); tRNA(s2UUG)(Gln) and tRNA(s2UUC)(Glu) suppressed a subset of the metabolic alterations observed in the elp3 Delta strain. Conclusion: Our results suggest that the presence of ncm(5)- and mcm(5)-side chains on wobble uridines in tRNA are important for metabolic homeostasis.
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