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Search: WFRF:(Rich K)

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4.
  • Aaltonen, T., et al. (author)
  • Combination of Tevatron Searches for the Standard Model Higgs Boson in the W+W- Decay Mode
  • 2010
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 104:6, s. 061802-
  • Journal article (peer-reviewed)abstract
    • We combine searches by the CDF and D0 Collaborations for a Higgs boson decaying to W+W-. The data correspond to an integrated total luminosity of 4.8 (CDF) and 5.4 (D0) fb(-1) of p (p) over bar collisions at root s = 1.96 TeV at the Fermilab Tevatron collider. No excess is observed above background expectation, and resulting limits on Higgs boson production exclude a standard model Higgs boson in the mass range 162-166 GeV at the 95% C.L.
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5.
  • Mishra, A., et al. (author)
  • Stroke genetics informs drug discovery and risk prediction across ancestries
  • 2022
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 611, s. 115-123
  • Journal article (peer-reviewed)abstract
    • Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry(1,2). Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and 1,013,843 control individuals, 87% of the primary stroke risk loci and 60% of the secondary stroke risk loci were replicated (P < 0.05). Effect sizes were highly correlated across ancestries. Cross-ancestry fine-mapping, in silico mutagenesis analysis(3), and transcriptome-wide and proteome-wide association analyses revealed putative causal genes (such as SH3PXD2A and FURIN) and variants (such as at GRK5 and NOS3). Using a three-pronged approach(4), we provide genetic evidence for putative drug effects, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as possible targets, with drugs already under investigation for stroke for F11 and PROC. A polygenic score integrating cross-ancestry and ancestry-specific stroke GWASs with vascular-risk factor GWASs (integrative polygenic scores) strongly predicted ischaemic stroke in populations of European, East Asian and African ancestry(5). Stroke genetic risk scores were predictive of ischaemic stroke independent of clinical risk factors in 52,600 clinical-trial participants with cardiometabolic disease. Our results provide insights to inform biology, reveal potential drug targets and derive genetic risk prediction tools across ancestries.
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6.
  • Abazov, V. M., et al. (author)
  • Direct observation of the strange b baryon Xi(-)(b)
  • 2007
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:5, s. 052001-
  • Journal article (peer-reviewed)abstract
    • We report the first direct observation of the strange b baryon Xi(-)(b)(Xi) over bar (+)(b)). We reconstruct the decay Xi(-)(b)-->J/psi Xi(-), with J/psi-->mu(+)mu(-), and Xi(-)-->Lambda pi(-)-->p pi(-)pi(-) in p (p) over bar collisions at root s = 1.96 TeV. Using 1.3 fb(-1) of data collected by the D0 detector, we observe 15.2 +/- 4.4(stat)(-0.4)(+1.9)(syst) Xi(-)(b) candidates at a mass of 5.774 +/- 0.011(stat) +/- 0.015(syst) GeV. The significance of the observed signal is 5.5 sigma, equivalent to a probability of 3.3 x 10(-8) of it arising from a background fluctuation. Normalizing to the decay Lambda(b)-->J/psi Lambda, we measure the relative rate sigma(Xi(-)(b))xB(Xi(-)(b)-->J/psi Xi)/ sigma(Lambda(b))xB(Lambda(b)-->J/psi Lambda) = 0.28 +/- 0.09(stat)(-0.08)(+0.09)(syst).
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7.
  • Abazov, V. M., et al. (author)
  • Measurement of the Lambda(0)(b) lifetime using semileptonic decays
  • 2007
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:18, s. 182001-
  • Journal article (peer-reviewed)abstract
    • We report a measurement of the Lambda(0)(b) lifetime using a sample corresponding to 1.3 fb(-1) of data collected by the D0 experiment in 2002-2006 during run II of the Fermilab Tevatron collider. The Lambda(0)(b) baryon is reconstructed via the decay Lambda(0)(b)->mu(nu) over bar Lambda X-+(c). Using 4437 +/- 329 signal candidates, we measure the Lambda(0)(b) lifetime to be tau(Lambda(0)(b))=1.290(-0.110)(+0.119)(stat)(-0.091)(+0.087)(syst) ps, which is among the most precise measurements in semileptonic Lambda(0)(b) decays. This result is in good agreement with the world average value.
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8.
  • Abazov, V. M., et al. (author)
  • Measurement of the Lambda(b) lifetime in the exclusive decay Lambda(b)-> J/psi Lambda
  • 2007
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:14, s. 142001-
  • Journal article (peer-reviewed)abstract
    • We have measured the Lambda(b) lifetime using the exclusive decay Lambda(b)-> J/psi Lambda, based on 1.2 fb(-1) of data collected with the D0 detector during 2002-2006. From 171 reconstructed Lambda(b) decays, where the J/psi and Lambda are identified via the decays J/psi ->mu(+)mu(-) and Lambda -> p pi, we measured the Lambda(b) lifetime to be tau(Lambda(b))=1.218(-0.115)(+0.130)(stat)+/- 0.042(syst) ps. We also measured the B-0 lifetime in the decay B-0 -> J/psi(mu(+)mu(-))K-S(0)(pi(+)pi(-)) to be tau(B-0)=1.501(-0.074)(+0.078)(stat)+/- 0.050(syst) ps, yielding a lifetime ratio of tau(Lambda(b))/tau(B-0)=0.811(-0.087)(+0.096)(stat)+/- 0.034(syst).
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9.
  • Abazov, V. M., et al. (author)
  • Measurement of the t(t)over-bar production cross section in p(p)over-bar collisions at root s=1.96 TeV using kinematic characteristics of lepton plus jets events
  • 2007
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 76:9
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the top quark pair production cross section in p (p) over bar collisions at root s=1.96 TeV utilizing 425 pb(-1) of data collected with the D0 detector at the Fermilab Tevatron Collider. We consider the final state of the top quark pair containing one high-p(T) electron or muon and at least four jets. We exploit specific kinematic features of t (t) over bar events to extract the cross section. For a top quark mass of 175 GeV, we measure sigma(t (t) over bar)=6.4(-1.2)(+1.3)(stat)+/- 0.7(syst)+/- 0.4(lum) pb, in good agreement with the standard model prediction.
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10.
  • Abazov, V. M., et al. (author)
  • Measurement of the t(t)over-bar production cross section in p(p)over-bar collisions using dilepton events
  • 2007
  • In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998. ; 76:5, s. 052006-
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the t (t) over bar pair production cross section in p (p) over bar collisions at root s=1.96 TeV utilizing approximately 425 pb(-1) of data collected with the D0 detector. We consider decay channels containing two high p(T) charged leptons (either e or mu) from leptonic decays of both top-daughter W bosons. These were gathered using four sets of selection criteria, three of which required that a pair of fully identified leptons (i.e., e mu, ee, or mu mu) be found. The fourth approach imposed less restrictive criteria on one of the lepton candidates and required that at least one hadronic jet in each event be tagged as containing a b quark. For a top quark mass of 175 GeV, the measured cross section is 7.4 +/- 1.4(stat)+/- 1.0(syst) pb and for the current Tevatron average top quark mass of 170.9 GeV, the resulting value of the cross section is 7.8 +/- 1.8(stat+syst) pb.
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11.
  • Abazov, V. M., et al. (author)
  • Properties of l=1 B-1 and B*(2) Mesons
  • 2007
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:17, s. 172001-
  • Journal article (peer-reviewed)abstract
    • This Letter presents the first strong evidence for the resolution of the excited B mesons B-1 and B-2(*) as two separate states in fully reconstructed decays to B+(*())pi(-). The mass of B-1 is measured to be 5720.6 +/- 2.4 +/- 1.4 MeV/c(2) and the mass difference Delta M between B-2* and B-1 is 26.2 +/- 3.1 +/- 0: 9 MeV/c(2), giving the mass of the B-2* as 5746.8 +/- 2.4 +/- 1.7 MeV/c(2). The production rate for B-1 and B-2* mesons is determined to be a fraction (13.9 +/- 1.9 +/- 3.2)% of the production rate of the B+ meson.
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12.
  • Abazov, V. M., et al. (author)
  • Search for a Higgs boson produced in association with a Z boson in p(p)over-bar collisions
  • 2007
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 655:5-6, s. 209-216
  • Journal article (peer-reviewed)abstract
    • We describe a search for the Standard Model Higgs boson with a mass of 105 GeV/c(2) to 145 GeV/c(2) in data corresponding to an integrated luminosity of approximately 450 pb(-1) collected with the D phi detector at the Fermilab Tevatron p (p) over bar collider at a center-of-mass energy of 1.96 TeV. The Higgs boson is required to be produced in association with a Z boson, and the Z boson is required to decay to either electrons or muons with the Higgs boson decaying to a b (b) over bar pair. The data are well described by the expected background, leading to 95% confidence level cross section upper limits sigma (p (p) over bar -> ZH) x B(H -> b (b) over bar) in the range of 3.1 pb to 4.4 pb.
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13.
  • Abazov, V. M., et al. (author)
  • Search for stopped gluinos from p(p)over-bar collisions at root s=1.96 TeV
  • 2007
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:13, s. 131801-
  • Journal article (peer-reviewed)abstract
    • Long-lived, heavy particles are predicted in a number of models beyond the standard model of particle physics. We present the first direct search for such particles' decays, occurring up to 100 h after their production and not synchronized with an accelerator bunch crossing. We apply the analysis to the gluino (g), predicted in split supersymmetry, which after hadronization can become charged and lose enough momentum through ionization to come to rest in dense particle detectors. Approximately 410 pb(-1) of p (p) over bar collisions at root s = 1.96 TeV collected with the D0 detector during Run II of the Fermilab Tevatron collider are analyzed in search of such "stopped gluinos" decaying into a gluon and a neutralino ((chi) over tilde (0)(1)). Limits are placed on the (gluino cross section) x (probability to stop) x [BR((g) over tilde -> g (chi) over tilde (0)(1))] as a function of the gluino and (chi) over tilde (0)(1) masses, for gluino lifetimes from 30 mu s-100 h.
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14.
  • Abazov, V. M., et al. (author)
  • Search for third-generation scalar leptoquarks in p(p)over-bar collisions at root s=1.96 TeV
  • 2007
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 99:6, s. 061801-
  • Journal article (peer-reviewed)abstract
    • We report on a search for charge-1/3 third-generation leptoquarks (LQ) produced in p (p) over bar collisions at root s =1.96 TeV using the D0 detector at Fermilab. Third-generation leptoquarks are assumed to be produced in pairs and to decay to a tau neutrino and a b quark with branching fraction B. We place upper limits on sigma(p (p) over bar -> LQ (LQ) over bar )B-2 as a function of the leptoquark mass M-LQ. Assuming B=1, we exclude at the 95% confidence level third-generation scalar leptoquarks with M-LQ < 229 GeV.
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15.
  • Abazov, V. M., et al. (author)
  • Z gamma production and limits on anomalous ZZ gamma and Z gamma gamma couplings in pp collisions at root s=1.96 TeV
  • 2007
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 653:5-6, s. 378-386
  • Journal article (peer-reviewed)abstract
    • We present a study of eey and mu mu gamma events using 1109 (1009) pb-(1) of data in the electron (muon) channel, respectively. These data were collected with the DO detector at the Fermilab Tevatron pp collider at Is = 1.96 TeV. Having observed 453 (515) candidates in the eey (jtAy) final state, we measure the Z gamma production cross section for a photon with transverse energy ET > 7 GeV, separation between the photon and leptons Delta Rey > 0.7, and invariant mass of the di-lepton pair Mee > 30 GeV/(2)(c), to be 4.96 0.30(stat. + syst.) zE 0.30(lumi.) pb, in agreement with the Standard Model prediction of 4.74 0.22 pb. This is the most precise Zy cross section measurement at a hadron collider. We set limits on anomalous trilinear Zyy and ZZy gauge boson couplings of -0.085 < h(30)(y) < 0.084, -0.0053 < h(40)(y) < 0.0054 and -0.083 < h(30)(Z) < 0.082, 30 40 30 -0.0053 < h(40)(Z) < 0.0054 at the 95% C.L. for the form-factor scale A = 1.2 TeV. 40 .
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16.
  • Pulit, S. L., et al. (author)
  • Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes
  • 2018
  • In: Neurology-Genetics. - : Ovid Technologies (Wolters Kluwer Health). - 2376-7839. ; 4:6
  • Journal article (peer-reviewed)abstract
    • Objective We sought to assess whether genetic risk factors for atrial fibrillation (AF) can explain cardioembolic stroke risk. We evaluated genetic correlations between a previous genetic study of AF and AF in the presence of cardioembolic stroke using genome-wide genotypes from the Stroke Genetics Network (N = 3,190 AF cases, 3,000 cardioembolic stroke cases, and 28,026 referents). We tested whether a previously validated AF polygenic risk score (PRS) associated with cardioembolic and other stroke subtypes after accounting for AF clinical risk factors. We observed a strong correlation between previously reported genetic risk for AF, AF in the presence of stroke, and cardioembolic stroke (Pearson r = 0.77 and 0.76, respectively, across SNPs with p < 4.4 x 10(-4) in the previous AF meta-analysis). An AF PRS, adjusted for clinical AF risk factors, was associated with cardioembolic stroke (odds ratio [OR] per SD = 1.40, p = 1.45 x 10(-48)), explaining similar to 20% of the heritable component of cardioembolic stroke risk. The AF PRS was also associated with stroke of undetermined cause (OR per SD = 1.07,p = 0.004), but no other primary stroke subtypes (all p > 0.1). Genetic risk of AF is associated with cardioembolic stroke, independent of clinical risk factors. Studies are warranted to determine whether AF genetic risk can serve as a biomarker for strokes caused by AF.
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17.
  • Abazov, V. M., et al. (author)
  • Search for B0s → μ+μ− decays at D0
  • 2007
  • In: Physical Review D. - : American Physical Society. - 1550-7998 .- 1550-2368. ; 76:9
  • Journal article (peer-reviewed)abstract
    • We report results from a search for the decay B0s → μ+μ− using 1.3  fb−1 of p¯p collisions at √s=1.96  TeV collected by the D0 experiment at the Fermilab Tevatron Collider. We find two candidate events, consistent with the expected background of 1.24±0.99, and set an upper limit on the branching fraction of B(B0s → μ+μ−)<1.2×10−7 at the 95% C.L.
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18.
  • Abazov, V. M., et al. (author)
  • Search for flavor-changing-neutral-current D meson decays
  • 2008
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:10, s. 101801-:100, s. 101801-
  • Journal article (peer-reviewed)abstract
    • We study the flavor-changing-neutral-current process c -> u mu(+)mu(-) using 1.3 fb(-1) of p (p) over bar collisions at root s = 1.96 TeV recorded by the D0 detector operating at the Fermilab Tevatron Collider. We see clear indications of the charged-current mediated D-s(+) and D+->phi pi(+)->mu(+)mu(-)pi(+) final states with significance greater than 4 standard deviations above background for the D+ state. We search for the continuum neutral-current decay of D+->pi(+)mu(+)mu(-) in the dimuon invariant mass spectrum away from the phi resonance. We see no evidence of signal above background and set a limit of B(D+->pi(+)mu(+)mu(-))< 3.9 x 10(-6) at the 90% C.L. This limit places the most stringent constraint on new phenomena in the c -> u mu(+)mu(-) transition.
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19.
  • Abazov, V. M., et al. (author)
  • Search for the lightest scalar top quark in events with two leptons in p(p)over-bar collisions at root s=1.96 TeV
  • 2008
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 659:3, s. 500-508
  • Journal article (peer-reviewed)abstract
    • Data collected by the DO detector at a p (p) over bar center-of-mass energy of 1.96 TeV at the Fermilab Tevatron Collider have been used to search for pair production of the lightest supersymmetric partner of the top quark decaying into bl (nu) over tilde. The search is performed in the ll' = e mu and mu mu final states. No evidence for this process has been found in data samples of approximately 400 pb(-1). The domain in the [M((t) over tilde (1)), M((nu) over tilde)] plane excluded at the 95% C.L. is substantially extended by this search.
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20.
  • Abazov, V. M., et al. (author)
  • A combined search for the standard model Higgs boson at root S=1.96 TeV
  • 2008
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 663:1-2, s. 26-36
  • Journal article (peer-reviewed)abstract
    • We present new results of the search for WH --> lvb (b) over bar production in p (p) over bar collisions at a center-of-mass energy of root S = 1.96 TeV, based on a dataset with integrated luminosity of 0.44 fb(-1). We combine these new results with previously published searches by the DO collaboration, for WH and ZH production analyzed in the E(T)b (b) over bar final state, for ZH (--> l(+)l(-)b (b) over bar) production, for WH (-->. WWW) production, and for H (--> W W) direct production. No signal-like excess is observed either in the W H analysis or in the combination of all D0 Higgs boson analyses. We set 95% C.L. (expected) upper limits on sigma(p (p) over bar --> WH) x B(H --> b (b) over bar) ranging from 1.6 (2.2) ph to 1.9 (3.3) pb for Higgs boson masses between 105 and 145 GeV, to be compared to the theoretical prediction of 0.13 pb for a Standard Model (SM) Higgs boson with mass in m(H) = 115 GeV. After combination with the other DO Higgs boson searches, we obtain for in H = 115 GeV an observed (expected) limit 8.5 (12.1) times higher than the SM predicted Higgs boson production cross section. For m(H) = 160 GeV, the corresponding observed (expected) ratio is 10.2 (9.0).
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21.
  • Abazov, V. M., et al. (author)
  • Evidence for the Decay B-s(0)->(DsDs(*))-D-(*) and a Measurement of Delta Gamma(CP)(s)/Gamma(s)
  • 2009
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:9, s. 091801-
  • Journal article (peer-reviewed)abstract
    • We search for the semi-inclusive process B-s(0)->(DsDs(*))-D-(*) using 2.8 fb(-1) of pp collisions at s=1.96 TeV recorded by the D0 detector operating at the Fermilab Tevatron Collider. We observe 26.6 +/- 8.4 signal events with a significance above background of 3.2 standard deviations yielding a branching ratio of B(B-s(0)->(DsDs(*))-D-(*))=0.035 +/- 0.010(stat.)+/- 0.011(syst.). Under certain theoretical assumptions, these double-charm final states saturate CP-even eigenstates in the B-s(0) decays resulting in a width difference of Delta Gamma(CP)(s)/Gamma(s)=0.072 +/- 0.021(stat.)+/- 0.022(syst.).
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22.
  • Abazov, V. M., et al. (author)
  • Measurement of sigma(p(p)over-bar -> Z plus X)Br(Z -> tau(+)tau(-)) at root s=1.96 TeV
  • 2009
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 670:4-5, s. 292-299
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the cross section for Z boson production times the branching fraction to tau lepton pairs sigma(p (p) over bar -> Z + X)Br(Z -> tau(+)tau(-)) in p (p) over bar collisions at root s = 1.96 TeV. The measurement is performed in the channel in which one tau lepton decays into a muon and neutrinos. and the other tau lepton decays hadronically or into an electron and neutrinos. The data sample corresponds to an integrated luminosity of 1.0 fb(-1) collected with the DO detector at the Fermilab Tevatron Collider. The sample contains 1511 candidate events with an estimated 20% background from jets or muons misidentified as tau leptons. We obtain sigma . Br = 240 +/- 8 (star) +/- 12 (sys) +/- 15 (lum) pb, which is consistent with the standard model prediction.
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23.
  • Abazov, V. M., et al. (author)
  • Measurement of the Angular and Lifetime Parameters of the Decays B-d(0) -> J/psi K*(0) and B-s(0) -> J/psi phi
  • 2009
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:3, s. 032001-:102, s. 032001-
  • Journal article (peer-reviewed)abstract
    • We present measurements of the linear polarization amplitudes and the strong relative phases that describe the flavor-untagged decays B-d(0) --> J/psi K*(0) and B-s(0) --> J/psi phi in the transversity basis. We also measure the mean lifetime (tau) over bar (s) of the B-s(0) mass eigenstates and the lifetime ratio (tau) over bar (s)/tau(d). The analyses are based on approximately 2.8 fb(-1) of data recorded with the D0 detector. From our measurements of the angular parameters we conclude that there is no evidence for a deviation from flavor SU( 3) symmetry for these decays and that the factorization assumption is not valid for the B-d(0) --> J/psi K*(0) decay.
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24.
  • Abazov, V. M., et al. (author)
  • Measurement of the forward-backward charge asymmetry in top-quark pair production
  • 2008
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 100:14:100, s. 142002-
  • Journal article (peer-reviewed)abstract
    • We present the first measurement of the integrated forward-backward charge asymmetry in top-quark-top-antiquark pair (t (t) over bar) production in proton-antiproton (p (p) over bar) collisions in the lepton+jets final state. Using a b-jet tagging algorithm and kinematic reconstruction assuming t (t) over bar +X production and decay, a sample of 0.9 fb(-1) of data, collected by the D0 experiment at the Fermilab Tevatron Collider, is used to measure the asymmetry for different jet multiplicities. The result is also used to set upper limits on t (t) over bar +X production via a Z' resonance.
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25.
  • Abazov, V. M., et al. (author)
  • Measurement of the muon charge asymmetry from W boson decays
  • 2008
  • In: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998. ; D:77, s. 011106-
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the muon charge asymmetry from W boson decays using 0.3 fb(-1) of data collected at root s =1.96 GeV between 2002 and 2004 with the D0 detector at the Fermilab Tevatron (p) over bar Collider. We compare our findings with expectations from next-to-leading-order calculations performed using the CTEQ6.1M and MRST04 NLO parton distribution functions. Our findings can be used to constrain future parton distribution function fits.
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