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Sökning: WFRF:(Sejersten M.)

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1.
  • Billgren, T, et al. (författare)
  • Detailed definition and interobserver agreement for the electrocardiographic Sclarovsky-Birnbaum ischemia grading system
  • 2002
  • Ingår i: Journal of Electrocardiology. - : Elsevier BV. - 1532-8430 .- 0022-0736. ; 35, s. 201-202
  • Tidskriftsartikel (refereegranskat)abstract
    • A generally implementable method for predicting salvageability on the presenting electrocardiogram (ECG) in patients with acute myocardial infarction (AMI) would be of great clinical importance. ECG-derived Grades of Ischemia (1) have been proven useful in predicting the extent and severity of left ventricular dysfunction after anterior MI, estimating short and long-term prognosis, final infarct size, and salvageability by reperfusion therapy (2).
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2.
  • Billgren, T, et al. (författare)
  • Refinement and interobserver agreement for the electrocardiographic Sclarovsky-Birnbaum Ischemia Grading System
  • 2004
  • Ingår i: Journal of Electrocardiology. - : Elsevier BV. - 1532-8430 .- 0022-0736. ; 37:3, s. 149-156
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Electrocardiogram-derived grades of ischemia at the time of patient presentation with acute myocardial infarction have proved useful in predicting the salvageability by reperfusion therapy, final infarct size, severity of left ventricular dysfunction, and short- and long-term prognosis. Subjects and Methods: The Sclarovsky-Birnbaum Ischemia Grading System based on the relation between the acute appearances of the T wave, the ST segment, and the QRS complex was considered as a means of enhanced ECG analysis in this group of patients. The evaluation of a training population (n = 46) resulted in refinement of the published description of the Sclarovsky-Birnbaum Ischemia Grading System, and a test population (n = 50) was utilized for investigating the interobserver agreement among 5 observers in determining the grade of ischemia. Results: The agreement among the observers applying the "refined" Sclarovsky-Birnbaum Ischemia Grading System was 0.89. Complete agreement was found for the ECGs of 80% of the patients, and the most common reason for disagreement was the application of the terminal T-negativity criterion. Conclusions: The refined Sclarovsky-Birnbaum Ischemia Grading System can be performed manually with low interobserver variability. It has potential for support of the acute myocardial infarction triage decision as an electrocardiographic method for evaluating the level of ischemic protection at the time of either pre-hospital or emergency-department presentation.
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4.
  • Hallén, Jonas, et al. (författare)
  • Influence of ST-segment recovery on infarct size and ejection fraction in patients with ST-segment elevation myocardial infarction receiving primary percutaneous coronary intervention.
  • 2010
  • Ingår i: The American journal of cardiology. - : Elsevier BV. - 1879-1913 .- 0002-9149. ; 105:9, s. 1223-8
  • Tidskriftsartikel (refereegranskat)abstract
    • In patients with ST-segment elevation myocardial infarction treated with fibrinolytics, electrocardiogram-derived measures of ST-segment recovery guide therapy decisions and predict infarct size. The comprehension of these relationships in patients undergoing mechanical reperfusion is limited. We studied 144 patients treated with primary percutaneous coronary intervention. We aimed to define the association between infarct size as determined by cardiac magnetic resonance imaging and different metrics of ST-segment recovery. Electrocardiograms were assessed at baseline and 90 minutes after primary percutaneous coronary intervention. Three methods for calculating and categorizing ST-segment recovery were used: (1) summed ST-segment deviation (STD) resolution analyzed in 3 categories (> or = 70%, > or = 30% to <70%, and <30%); (2) single-lead STD resolution analyzed in the same 3 categories; (3) worst-lead residual STD analyzed in 3 categories (<1 mm, 1 to <2 mm, and > or = 2 mm). Infarct size and ejection fraction were assessed at 4 months by cardiac magnetic resonance imaging. All 3 ST-segment recovery algorithms predicted the final infarct size and cardiac function. Worst-lead residual STD performed the same as, or better than, the more complex methods and identified large subgroups at either end of the risk spectrum (median infarct size from the lowest to highest risk category (percentage of left ventricle: 7.7% [interquartile range 10.8], 13.1% [interquartile range 13.6]; 24.6% [interquartile range 21.1]); with adjusted odds ratios for infarct size greater than the median (reference <1 mm): 1 to <2 mm, odds ratio 2.3 (95% confidence interval 0.8 to 5.9); > or = 2 mm, odds ratio 6.3 (95% confidence interval 1.7 to 23.7; c-index 0.781). In conclusion, an electrocardiogram obtained early after primary percutaneous coronary intervention analyzed by a simple algorithm provided prognostic information on the final infarct size and cardiac function.
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5.
  • Sejersten, M, et al. (författare)
  • Comparison of EASI-derived 12-lead electrocardiograms versus paramedic-acquired 12-lead electrocardiograms using Mason-Likar limb lead configuration in patients with chest pain
  • 2006
  • Ingår i: Journal of Electrocardiology. - : Elsevier BV. - 1532-8430 .- 0022-0736. ; 39:1, s. 13-21
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: Monitoring of serial 12-lead electrocardiogram (ECG) recordings is the accepted requirement for prehospital data acquisition in patients with chest pain. The purpose of this study was to determine whether waveforms and clinical triage decisions are similar for EASI-derived ECGs and paramedic-acquired 12-lead ECGs using Mason-Likar limb lead configuration when compared with standard 12-lead ECGs (stdECG). Method: Twenty patients with chest pain had a prehospital 12-lead ECG recorded in the ambulance, and paramedic-applied electrodes retained in place at hospital arrival. An ECG technician applied standard precordial and EASI electrodes in their Correct positions. Twelve-lead ECGs were obtained from the paramedic-applied electrodes using their Mason-Likar limb lead configuration, and derived from the EASI leads for comparison with the stdECG. Three computer-measured QRS-T waveform parameters were considered, and differences in waveform measurement between EASI and stdECG (EASI Delta stdECG) versus differences in waveform measurements between paramedic Mason-Likar and stdECG (PML Delta stdECG) were calculated. Two emergency physicians determined whether the EASI-derived or the paramedic Mason-Likar ECG contained information that would change their clinical triage decision from that indicated by the stdECG. Results: EASI Delta stdECG and PML Delta stdECG were identical in 28%, whereas EASI Delta stdECG was more than PML Delta stdECG in 35%, and PML Delta stdECG was accurate (both times) than EASI Delta stdECG in 37% (P = .62). The physicians were more likely to change the level of patient care based on the EASI-derived ECGs compared with the paramedic ECGs; however, this difference was not statistically significant (P = .27), but this may only be caused by the small study population. Conclusions: There are similar differences from stdECG waveforms in EASI-derived ECGs and those acquired via paramedic-applied precordial electrodes using Mason-Likar limb lead configuration. Either method can be used as a substitute for monitoring, but neither should be considered equivalent to the stdECG for diagnostic purposes. (c) 2006 Elsevier Inc. All rights reserved.
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6.
  • Sejersten, M, et al. (författare)
  • The relative accuracies of ECG precordial lead waveforms derived from EASI leads and those acquired from paramedic applied standard leads
  • 2003
  • Ingår i: Journal of Electrocardiology. - 1532-8430. ; 36:3, s. 179-185
  • Tidskriftsartikel (refereegranskat)abstract
    • Accurate precordial electrode placement can be difficult in emergency situations leading either to loss of time or diminished accuracy. A possible solution is the quasi-orthogonal EASI lead system, with only five electrodes and easily defined landmarks to provide a derived 12-lead electrocardiogram (ECG). The purpose of this study was to test the hypothesis that precordial waveforms in EASI-derived ECGs have no greater deviation from those in gold standard ECGs, than do the precordial waveforms in paramedic acquired standard ECGs. Twenty paramedics applied the standard precordial electrodes employing the routine procedure. A certified ECG technician applied the 6 standard precordial electrodes in their correct gold standard positions, and the EASI electrodes. 12-lead ECGs were obtained from the paramedics' standard leads, and derived from the EASI leads, for comparison with the gold standard ECG. In each precordial lead recording, 6 computer-measured QRS-T waveform parameters were considered. Differences between DeltaEASI-gold standard versus Deltaparamedic-gold standard were calculated for every waveform in every lead resulting in 720 comparisons. EASI and paramedic results were "equally accurate" in 47%, the paramedic was more accurate in 31%, and EASI was more accurate in the remaining 22%. The differences from gold standard recording of precordial waveforms in ECGs derived from the EASI leads and those acquired via paramedic-applied standard electrodes are similar. The results suggest that the EASI lead system may provide an alternative,to the standard ECG precordial leads to facilitate data acquisition and possibly save valuable time in emergency situations.
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