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- Clark, Andrew G., et al.
(author)
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Evolution of genes and genomes on the Drosophila phylogeny
- 2007
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In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 450:7167, s. 203-218
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Journal article (peer-reviewed)abstract
- Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
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11. |
- Margutti, R., et al.
(author)
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A PANCHROMATIC VIEW OF THE RESTLESS SN 2009ip REVEALS THE EXPLOSIVE EJECTION OF A MASSIVE STAR ENVELOPE
- 2014
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In: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 780:1
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Journal article (peer-reviewed)abstract
- The double explosion of SN 2009ip in 2012 raises questions about our understanding of the late stages of massive star evolution. Here we present a comprehensive study of SN 2009ip during its remarkable rebrightenings. High-cadence photometric and spectroscopic observations from the GeV to the radio band obtained from a variety of ground-based and space facilities (including the Very Large Array, Swift, Fermi, Hubble Space Telescope, and XMM) constrain SN 2009ip to be a low energy (E similar to 1050 erg for an ejecta mass similar to 0.5 M-circle dot) and asymmetric explosion in a complex medium shaped by multiple eruptions of the restless progenitor star. Most of the energy is radiated as a result of the shock breaking out through a dense shell of material located at similar to 5 x 10(14) cm with M similar to 0.1 M-circle dot, ejected by the precursor outburst similar to 40 days before the major explosion. We interpret the NIR excess of emission as signature of material located further out, the origin of which has to be connected with documented mass-loss episodes in the previous years. Our modeling predicts bright neutrino emission associated with the shock break-out if the cosmic-ray energy is comparable to the radiated energy. We connect this phenomenology with the explosive ejection of the outer layers of the massive progenitor star, which later interacted with material deposited in the surroundings by previous eruptions. Future observations will reveal if the massive luminous progenitor star survived. Irrespective of whether the explosion was terminal, SN 2009ip brought to light the existence of new channels for sustained episodic mass loss, the physical origin of which has yet to be identified.
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12. |
- Andrews, Jennifer E., et al.
(author)
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SN 2017gmr : An Energetic Type II-P Supernova with Asymmetries
- 2019
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In: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 885:1
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Journal article (peer-reviewed)abstract
- We present high-cadence UV, optical, and near-infrared data on the luminous Type II-P supernova SN;2017gmr from hours after discovery through the first 180 days. SN;2017gmr does not show signs of narrow, high-ionization emission lines in the early optical spectra, yet the optical light-curve evolution suggests that an extra energy source from circumstellar medium (CSM) interaction must be present for at least 2 days after explosion. Modeling of the early light curve indicates a ?500 R progenitor radius, consistent with a rather compact red supergiant, and late-time luminosities indicate that up to 0.130;;0.026 M of Ni-56 are present, if the light curve is solely powered by radioactive decay, although the Ni-56 mass may be lower if CSM interaction contributes to the post-plateau luminosity. Prominent multipeaked emission lines of H? and [O i] emerge after day 154, as a result of either an asymmetric explosion or asymmetries in the CSM. The lack of narrow lines within the first 2 days of explosion in the likely presence of CSM interaction may be an example of close, dense, asymmetric CSM that is quickly enveloped by the spherical supernova ejecta.
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13. |
- Tartaglia, Leonardo, et al.
(author)
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The Early Discovery of SN 2017ahn : Signatures of Persistent Interaction in a Fast-declining Type II Supernova
- 2021
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In: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 907:1
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Journal article (peer-reviewed)abstract
- We present high-cadence, comprehensive data on the nearby (D 33 Mpc) Type II supernova (SN II) 2017ahn, discovered within about one day of the explosion, from the very early phases after explosion to the nebular phase. The observables of SN 2017ahn show a significant evolution over the 470 days of our follow-up campaign, first showing prominent, narrow Balmer lines and other high-ionization features purely in emission (i.e., flash spectroscopy features), which progressively fade and lead to a spectroscopic evolution similar to that of more canonical SNe II. Over the same period, the decline of the light curves in all bands is fast, resembling the photometric evolution of linearly declining H-rich core-collapse SNe. The modeling of the light curves and early flash spectra suggests that a complex circumstellar medium surrounds the progenitor star at the time of explosion, with a first dense shell produced during the very late stages of its evolution that is swept up by the rapidly expanding ejecta within the first ~6 days of the SN evolution, while signatures of interaction are observed also at later phases. Hydrodynamical models support the scenario in which linearly declining SNe II are predicted to arise from massive yellow super- or hypergiants depleted of most of their hydrogen layers.
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14. |
- Tetarenko, B. E., et al.
(author)
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The First Low-Mass Black Hole X-Ray Binary Identified in Quiscence Outside of a Globular Cluster
- 2016
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In: Astrophysical Journal. - 1538-4357 .- 0004-637X. ; 825:1
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Journal article (peer-reviewed)abstract
- The observed relation between the X-ray and radio properties of low-luminosity accreting black holes (BHs) has enabled the identification of multiple candidate black hole X-ray binaries (BHXBs) in globular clusters (GCs). Here, we report an identification of the radio source VLA J213002.08+120904 (aka M15 S2), recently reported in Kirsten et al., as a BHXB candidate. They showed that the parallax of this flat-spectrum variable radio source indicates a - + 2.2 0.30.5 kpc distance, which identifies it as lying in the foreground of the GC M15. We determine the radio characteristics of this source and place a deep limit on the X-ray luminosity of ∼4 × 1029 erg s.1. Furthermore, we astrometrically identify a faint red stellar counterpart in archival Hubble images with colors consistent with a foreground star; at 2.2 kpc, its inferred mass is 0.1-0.2Me. We rule out that this object is a pulsar, neutron star X-ray binary, cataclysmic variable, or planetary nebula, concluding that VLA J213002.08+120904 is the first accreting BHXB candidate discovered in quiescence outside of a GC. Given the relatively small area over which parallax studies of radio sources have been performed, this discovery suggests a much larger population of quiescent BHXBs in our Galaxy, 2.6 ± 104-1.7 × 108 BHXBs at 3× confidence, than has been previously estimated (∼102-104) through population synthesis.The observed relation between the X-ray and radio properties of low-luminosity accreting black holes (BHs) has enabled the identification of multiple candidate black hole X-ray binaries (BHXBs) in globular clusters (GCs). Here, we report an identification of the radio source VLA J213002.08+120904 (aka M15 S2), recently reported in Kirsten et al., as a BHXB candidate. They showed that the parallax of this flat-spectrum variable radio source indicates a - + 2.2 0.30.5 kpc distance, which identifies it as lying in the foreground of the GC M15. We determine the radio characteristics of this source and place a deep limit on the X-ray luminosity of ∼4 × 1029 erg s.1. Furthermore, we astrometrically identify a faint red stellar counterpart in archival Hubble images with colors consistent with a foreground star; at 2.2 kpc, its inferred mass is 0.1-0.2Me. We rule out that this object is a pulsar, neutron star X-ray binary, cataclysmic variable, or planetary nebula, concluding that VLA J213002.08+120904 is the first accreting BHXB candidate discovered in quiescence outside of a GC. Given the relatively small area over which parallax studies of radio sources have been performed, this discovery suggests a much larger population of quiescent BHXBs in our Galaxy, 2.6 ± 104-1.7 × 108 BHXBs at 3× confidence, than has been previously estimated (∼102-104) through population synthesis.
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15. |
- Bianco, Federica B., et al.
(author)
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Optimization of the Observing Cadence for the Rubin Observatory Legacy Survey of Space and Time : A Pioneering Process of Community-focused Experimental Design
- 2022
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In: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 258:1
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Journal article (peer-reviewed)abstract
- Vera C. Rubin Observatory is a ground-based astronomical facility under construction, a joint project of the National Science Foundation and the U.S. Department of Energy, designed to conduct a multipurpose 10 yr optical survey of the Southern Hemisphere sky: the Legacy Survey of Space and Time. Significant flexibility in survey strategy remains within the constraints imposed by the core science goals of probing dark energy and dark matter, cataloging the solar system, exploring the transient optical sky, and mapping the Milky Way. The survey's massive data throughput will be transformational for many other astrophysics domains and Rubin's data access policy sets the stage for a huge community of potential users. To ensure that the survey science potential is maximized while serving as broad a community as possible, Rubin Observatory has involved the scientific community at large in the process of setting and refining the details of the observing strategy. The motivation, history, and decision-making process of this strategy optimization are detailed in this paper, giving context to the science-driven proposals and recommendations for the survey strategy included in this Focus Issue.
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16. |
- Chomiuk, Laura, et al.
(author)
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Classical Novae at Radio Wavelengths
- 2021
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In: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 257:2
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Journal article (peer-reviewed)abstract
- We present radio observations (1-40 GHz) for 36 classical novae, representing data from over five decades compiled from the literature, telescope archives, and our own programs. Our targets display a striking diversity in their optical parameters (e.g., spanning optical fading timescales, t (2) = 1-263 days), and we find a similar diversity in the radio light curves. Using a brightness temperature analysis, we find that radio emission from novae is a mixture of thermal and synchrotron emission, with nonthermal emission observed at earlier times. We identify high brightness temperature emission (T ( B ) > 5 x 10(4) K) as an indication of synchrotron emission in at least nine (25%) of the novae. We find a class of synchrotron-dominated novae with mildly evolved companions, exemplified by V5589 Sgr and V392 Per, that appear to be a bridge between classical novae with dwarf companions and symbiotic binaries with giant companions. Four of the novae in our sample have two distinct radio maxima (the first dominated by synchrotron and the later by thermal emission), and in four cases the early synchrotron peak is temporally coincident with a dramatic dip in the optical light curve, hinting at a common site for particle acceleration and dust formation. We publish the light curves in a machine-readable table and encourage the use of these data by the broader community in multiwavelength studies and modeling efforts.
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17. |
- Chomiuk, Laura, et al.
(author)
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A DEEP SEARCH FOR PROMPT RADIO EMISSION FROM THERMONUCLEAR SUPERNOVAE WITH THE VERY LARGE ARRAY
- 2016
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In: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 821:2
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Journal article (peer-reviewed)abstract
- Searches for circumstellar material around Type Ia supernovae (SNe Ia) are some of the most powerful tests of the nature of SN Ia progenitors, and radio observations provide a particularly sensitive probe of this material. Here, we report radio observations for SNe. Ia and their lower-luminosity thermonuclear cousins. We present the largest, most sensitive, and spectroscopically diverse study of prompt (Delta t less than or similar to 1 years) radio observations of 85 thermonuclear SNe, including 25 obtained by our team with the unprecedented depth of the Karl G. Jansky Very Large Array. With these observations, SN 2012cg joins SN 2011fe and SN 2014J as an SN. Ia with remarkably deep radio limits and excellent temporal coverage (six epochs, spanning 5-216 days after explosion, implying <(M)over dot>/v(w) less than or similar to 5 x 10(-9) M-circle dot yr(-1)/100 km s(-1), assuming epsilon(B) = 0.1 and epsilon(e) = 0.1). All observations yield non-detections, placing strong constraints on the presence of circumstellar material. We present analytical models for the temporal and spectral evolution of prompt radio emission from thermonuclear SNe as expected from interaction with either wind-stratified or uniform density media. These models allow us to constrain the progenitor mass loss rates, with limits in the range of <(M)over dot> less than or similar to 10(-9) - 10(-4) M-circle dot yr(-1), assuming a wind velocity of v(w) = 100 km s(-1). We compare our radio constraints with measurements of Galactic symbiotic binaries to conclude that less than or similar to 10% of thermonuclear SNe have red giant companions.
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18. |
- Hosseinzadeh, Griffin, et al.
(author)
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Constraining the Progenitor System of the Type Ia Supernova 2021aefx
- 2022
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In: Astrophysical Journal Letters. - : American Astronomical Society. - 2041-8205 .- 2041-8213. ; 933:2
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Journal article (peer-reviewed)abstract
- We present high-cadence optical and ultraviolet light curves of the normal Type Ia supernova (SN) 2021aefx, which shows an early bump during the first two days of observation. This bump may be a signature of interaction between the exploding white dwarf and a nondegenerate binary companion, or it may be intrinsic to the white dwarf explosion mechanism. In the case of the former, the short duration of the bump implies a relatively compact main-sequence companion star, although this conclusion is viewing-angle dependent. Our best-fit companion-shocking and double-detonation models both overpredict the UV luminosity during the bump, and existing nickel-shell models do not match the strength and timescale of the bump. We also present nebular spectra of SN 2021aefx, which do not show the hydrogen or helium emission expected from a nondegenerate companion, as well as a radio nondetection that rules out all symbiotic progenitor systems and most accretion disk winds. Our analysis places strong but conflicting constraints on the progenitor of SN 2021aefx; no current model can explain all of our observations.
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19. |
- Simons, Michelle, et al.
(author)
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Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin : implications for the design of hemoglobin-based oxygen carriers
- 2018
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In: Bioscience Reports. - 0144-8463. ; 38:4
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Journal article (peer-reviewed)abstract
- Hemoglobin (Hb)-based oxygen carriers (HBOCs) have been engineered to replace or augment the oxygen carrying capacity of erythrocytes. However, clinical results have generally been disappointing, in part due to the intrinsic oxidative toxicity of Hb. The most common HBOC starting material is adult human or bovine Hb. However, it has been suggested that fetal Hb may offer advantages due to decreased oxidative reactivity. Large-scale manufacturing of HBOC will likely and ultimately require recombinant sources of human proteins. We, therefore, directly compared the functional properties and oxidative reactivity of recombinant fetal (rHbF) and recombinant adult (rHbA) Hb. rHbA and rHbF produced similar yields of purified functional protein. No differences were seen in the two proteins in: autoxidation rate; the rate of hydrogen peroxide reaction; NO scavenging dioxygenase activity; and the NO producing nitrite reductase activity. The rHbF protein was: less damaged by low levels of hydrogen peroxide; less damaging when added to human umbilical vein endothelial cells (HUVEC) in the ferric form; and had a slower rate of intrinsic heme loss. The rHbA protein was: more readily reducible by plasma antioxidants such as ascorbate in both the reactive ferryl and ferric states; less readily damaged by lipid peroxides; and less damaging to phosphatidylcholine liposomes. In conclusion in terms of oxidative reactivity, there are advantages and disadvantages to the use of rHbA or rHbF as the basis for an effective HBOC.
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