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1.	Gonzalez, CA, et al. (author) Smoking and the risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 2003 In: International Journal of Cancer. - : Wiley. - 0020-7136. ; 107:4, s. 629-634 Journal article (peer-reviewed)abstract Smoking has recently been recognised as causally associated with the development of gastric cancer (GC). However, evidence on the effect by sex, duration and intensity of smoking, anatomic subsite and cessation of smoking is limited. Our objective was to assess the relation between tobacco use and GC incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC). We studied data from 521,468 individuals recruited from 10 European countries taking part in the EPIC study. Participants completed lifestyle questionnaires that included questions on lifetime consumption of tobacco and diet in 1991-1998. Participants were followed until September 2002, and during that period 305 cases of stomach cancer were identified. After exclusions, 274 were eligible for the analysis, using the Cox proportional hazard model. After adjustment for educational level, consumption of fresh fruit, vegetables and preserved meat, alcohol intake and body mass index (BMI), there was a significant association between cigarette smoking and gastric cancer risk: the hazard ratio (HR) for ever smokers was 1.45 (95% confidence interval [CI] = 1.08-1.94). The HR of current cigarette smoking was 1.73 (95% CI = 1.06-2.83) in males and 1.87 (95% CI = 1.12-3.12) in females. Hazard ratios increased with intensity and duration of cigarette smoked. A significant decrease of risk was observed after 10 years of quitting smoking. A preliminary analysis of 121 cases with identified anatomic site showed that current cigarette smokers had a higher HR of GC in the cardia (HR = 4.10) than in the distal part of the stomach (HR = 1.94). In this cohort, 17.6 % (95% CI = 10.5-29.5 %) of GC cases may be attributable to smoking. Findings from this large study support the causal relation between smoking and gastric cancer in this European population. Stomach cancer should be added to the burden of diseases caused by smoking. (C) 2003 Wiley-Liss, Inc.
2.	Hyvonen, R., et al. (author) The likely impact of elevated [CO2], nitrogen deposition, increased temperature and management on carbon sequestration in temperate and boreal forest ecosystems: a literature review 2007 In: New Phytologist. - Cambridge : Wiley. - 0028-646X .- 1469-8137. ; 173:3, s. 463-480 Research review (peer-reviewed)abstract Temperate and boreal forest ecosystems contain a large part of the carbon stored on land, in the form of both biomass and soil organic matter. Increasing atmospheric [CO2], increasing temperature, elevated nitrogen deposition and intensified management will change this C store. Well documented single-factor responses of net primary production are: higher photosynthetic rate (the main [CO2] response); increasing length of growing season (the main temperature response); and higher leaf-area index (the main N deposition and partly [CO2] response). Soil organic matter will increase with increasing litter input, although priming may decrease the soil C stock initially, but litter quality effects should be minimal (response to [CO2], N deposition, and temperature); will decrease because of increasing temperature; and will increase because of retardation of decomposition with N deposition, although the rate of decomposition of high-quality litter can be increased and that of low-quality litter decreased. Single-factor responses can be misleading because of interactions between factors, in particular those between N and other factors, and indirect effects such as increased N availability from temperature-induced decomposition. In the long term the strength of feedbacks, for example the increasing demand for N from increased growth, will dominate over short-term responses to single factors. However, management has considerable potential for controlling the C store.
3.	Manjer, Jonas, et al. (author) Postmenopausal breast cancer risk in relation to sex steroid hormones, prolactin and SHBG (Sweden) 2003 In: Cancer Causes and Control. - 1573-7225. ; 14:7, s. 599-607 Journal article (peer-reviewed)abstract Objective: High levels of sex steroid hormones and prolactin have been suggested to enhance breast cancer development. Low levels of SHBG may indicate high levels of (bio-available) steroid hormones. The present study investigates whether high levels of sex steroid hormones and prolactin, and/or low levels of SHBG, are associated with high breast cancer risk. Methods: Blood samples were collected in about 65,000 women participating in two population-based prospective cohort studies in Sweden. Follow-up yielded 173 postmenopausal breast cancer cases who had not been exposed to HRT. Levels of estrone, estradiol, SHBG, FSH, prolactin, testosterone, androstenedione and DHEAs were analysed in cases and 438 controls. Logistic regression analysis yielded odds ratios (ORs), with 95% confidence intervals, adjusted for potential confounders. Results: The risk of breast cancer was associated with the highest versus lowest quartiles of estrone, OR: 2.58 (1.50 - 4.44), estradiol (dichotomised: high versus low) (1.73: 1.04 - 2.88), and testosterone (1.87: 1.08 - 3.25). High risks, although not statistically significant, were seen for androstenedione (1.58: 0.92 - 2.72) and DHEAs ( 1.62: 0.89 - 2.72). No strong associations were seen between SHBG or prolactin and risk of breast cancer. Conclusions: High levels of estrone, estradiol, testosterone, and possibly androstenedione and DHEAs, in postmenopausal women are associated with a high risk of subsequent breast cancer.
4.	Mirastschijski, U, et al. (author) Epithelial regeneration from bioengineered skin explants in culture. 2006 In: The British journal of dermatology. - : Oxford University Press (OUP). - 0007-0963. ; 154:1, s. 42-9 Journal article (peer-reviewed)abstract BACKGROUND: Artificial skin substitutes are beneficial in the treatment of chronic wounds although their performance relative to authentic human skin is unclear. OBJECTIVES: We compared the rate of outgrowth and morphology of neoepidermis from a bioengineered skin construct (Apligraf) with normal adult human skin explants on de-epidermized human dermal growth substrate with or without intact epidermal basement membrane zone. METHODS: Epithelial outgrowth of air-exposed cultures in serum-supplemented keratinocyte medium was quantified by fluorescence imaging, morphology by light microscopy, biomarkers of keratinocyte activation, proliferation and migration by immunohistochemical analysis, and gelatinases by zymography. RESULTS: Resurfacing from bioengineereed skin explants started earlier than from normal skin but subsequently, from day 3 to day 9, the rate of epidermalization from bioengineered skin was only 40% (206 +/- 23 microm day(-1), mean +/- SEM) of that of authentic skin (521 +/- 17 microm day(-1), P < 0.001). At culture termination at day 11, normal human skin had formed a multilayered and well-structured neoepidermis covering 41.0 +/- 1.2 mm2 of the dermal substrate while bioengineered skin produced a thinner, less organized epithelium covering 20.4 +/- 3.0 mm2. At this later stage, a higher expression of beta-defensin-2, keratin 16, Ki67 and matrix metalloproteinase (MMP)-9 was found in neoepidermis formed from authentic skin than from bioengineered skin. Activated MMP-2 was elevated in bioengineered skin-derived neoepidermis. Minor epithelial outgrowth was noted with either skin type on the dermal substrate devoid of basement membrane zone. CONCLUSIONS: Cultured normal skin explants produced a more uniform and expansive in vivo-like neoepidermis than bioengineered skin explants.
5.	Agren Bolmsjö, I, et al. (author) From cure to palliation: agreement, timing, and decision making within the staff 2007 In: The American journal of hospice & palliative care. - : SAGE Publications. - 1049-9091 .- 1938-2715. ; 24:5, s. 366-70 Journal article (peer-reviewed)abstract Important issues in the transition From curative treatment to palliative care are agreement, timing, and decision making. A survey oF 309 nurses and 415 physicians in Sweden showed that 61% oF the nurses and 83% oF the physicians thought agreement was current practice. None said that the decisions were made too early, but 19% oF the nurses and 14% oF the physicians thought that they oFten were made too late. Very Few respondents stated that such decisions are changed, 0% and 1%, respectively. More than halF oF the inFormants made detailed comments on such transitions indicating that awareness and Flexibility are desirable to make well-inFormed decisions. Three themes that emerged From the analysis concerning the decision to stop curative treatment and Focus on palliative care were that the staFF members should (iF possible) make such decisions in agreement and should sometimes make the decisions earlier and that well-based reasons are required to make changes.
6.	Agren, D, et al. (author) Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria 2008 In: The Journal of biological chemistry. - 0021-9258. ; 283:46, s. 31567-31574 Journal article (peer-reviewed)
7.	Agren, D, et al. (author) The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity 2009 In: FEBS letters. - : Wiley. - 1873-3468 .- 0014-5793. ; 583:2, s. 330-336 Journal article (peer-reviewed)
8.	Agren, M, et al. (author) Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site 2004 In: Gene. - : Elsevier BV. - 0378-1119. ; 330, s. 101-114 Journal article (peer-reviewed)
9.	Agren, R, et al. (author) Low-Resistance silver bromide electrodes for recording fast ion channel kinetics under voltage clamp conditions 2021 In: Journal of neuroscience methods. - : Elsevier BV. - 1872-678X .- 0165-0270. ; 348, s. 108984- Journal article (peer-reviewed)
10.	Agren, R, et al. (author) Point mutation of a conserved aspartate, D69, in the muscarinic M2 receptor does not modify voltage-sensitive agonist potency 2018 In: Biochemical and biophysical research communications. - : Elsevier BV. - 1090-2104 .- 0006-291X. ; 496:1, s. 101-104 Journal article (peer-reviewed)
11.	Agren, R, et al. (author) The Beta-Arrestin-Biased Dopamine D2 Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation 2018 In: The international journal of neuropsychopharmacology. - : Oxford University Press (OUP). - 1469-5111 .- 1461-1457. ; 21:12, s. 1102-1108 Journal article (peer-reviewed)
12.	Agren, R (author) Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data 2021 In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 11:1, s. 13136- Journal article (peer-reviewed)abstract Prescription patterns of antipsychotic drugs (APDs) are typically sourced from country-specific data. In this study, a digital pharmacoepidemiological approach was used to investigate APD preferences globally. Publicly available data on worldwide web search intensities in Google for 19 typical and 22 atypical APDs were temporally and spatially normalized and correlated with reported prescription data. The results demonstrated an increasing global preference for atypical over typical APDs since 2007, with quetiapine, olanzapine, risperidone, and aripiprazole showing the largest search intensities in 2020. Cross-sectional analysis of 122 countries in 2020 showed pronounced differences in atypical/typical APD preferences that correlated with gross domestic product per capita. In conclusion, the investigation provides temporal and spatial assessments of global APD preferences and shows a trend towards atypical APDs, although with a relative preference for typical APDs in low-income countries. Similar data-sourcing methodologies allow for prospective studies of other prescription drugs.
13.	Beskow, C, et al. (author) Pathologic complete remission after preoperative intracavitary radiotherapy of cervical cancer stage Ib and IIa is a strong prognostic factor for long-term survival: analysis of the Radiumhemmet data 1989-1991 2002 In: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. - : BMJ. - 1048-891X. ; 12:2, s. 158-170 Journal article (peer-reviewed)
14.	Danielsson, R, et al. (author) Comparison of planar and SPECT scintimammography with 99mTc-sestamibi in the diagnosis of breast carcinoma 1999 In: Acta radiologica (Stockholm, Sweden : 1987). - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 40:2, s. 176-180 Journal article (peer-reviewed)abstract Purpose: To compare results of planar and SPECT breast imaging with 99mTc-MIBI in detecting primary breast cancer. Material and Methods: Twenty-six consecutive patients with 34 suspected breast lesions underwent both planar and SPECT scintimammography. Ten minutes after injection of 700 MBq 99mTc-MIBI, 2 prone lateral projections were obtained, followed by a supine anterior projection. Forty minutes after injection, a SPECT study was done. All lesions were operated upon and verified with histopathology. Results: A sensitivity of 85% and specificity of 88% of planar scintimammography in diagnosis of primary breast lesions were achieved. The corresponding values for SPECT were 61% and 64%. Conclusion: The diagnostic accuracy of planar scintimammography was not improved by using SPECT imaging.
15.	Engelmark, O., et al. (author) Ecological effects and management aspects of an exotic tree species : the case of lodgepole pine in Sweden 2001 In: Forest Ecology and Management. - 0378-1127 .- 1872-7042. ; 141:02-jan, s. 3-13 Journal article (peer-reviewed)abstract The North American tree Pinus contorta var, latifolia was experimentally introduced in Sweden already in the 1920s, and has been used in Swedish forestry on a large scale since the 1970s. These plantations now cover 565,000 ha, mainly in the northern area. In this paper we summarize and discuss existing ecological knowledge of this species introduction. With regard to longterm sustainability we suggest management means to minimize harmful effects of the introduction on ecosystems. These include aspects of self dispersal, pests, ecosystem and landscape structures, and also ecological processes and biodiversity. We also focus on observed and possible interactions in the ecosystems. As Pinus contorta seeds are disseminated and trees regenerated outside initial plantations, this may have future bearings on biodiversity. We suggest a strategy which takes account of the uncertainty in predicting future ecological effects. The strategy includes areal restrictions and zones without Pinus contorta, but also to set up a monitoring program. Observations of adverse effects from the plantations would then give the possibility to adjust P. contorta management.
16.	Fast, L, et al. (author) Fluorescence-Based Measurements of Membrane-Bound Angiotensin Converting Enzyme 2 Activity Using Xenopus Laevis Oocytes 2022 In: Biosensors. - : MDPI AG. - 2079-6374. ; 12:8 Journal article (peer-reviewed)abstract Functional investigations of enzymes involving cellular expression systems are important for pharmacological studies. The precise control of expression is challenging in transiently transfected mammalian cell lines. Here, we explored the ability of Xenopus laevis oocytes to express a membrane-bound enzyme for functional characterization using standard 96-well plates and a fluorescence-based plate reader assay. We microinjected oocytes with cRNA encoding the angiotensin converting enzyme 2 (ACE2) and measured the enzymatic activity in single oocytes using a commercial fluorescence-based assay. The injected oocytes showed up to a 50-fold increase in fluorescence compared to uninjected oocytes. This fluorescence intensity was dose-dependent on the amount of ACE2 cRNA. These results suggest that Xenopus oocytes can be used for the functional evaluation of membrane-bound enzymes, decreasing the experimental workload.
17.	Feifel, R, et al. (author) Observation of a continuum-continuum interference hole in ultrafast dissociating core-excited molecules 2000 In: PHYSICAL REVIEW LETTERS. - : AMERICAN PHYSICAL SOC. - 0031-9007. ; 85:15, s. 3133-3136 Journal article (peer-reviewed)abstract The femtosecond dissociation of HCl after core excitation has been studied through the resonant Auger decay. The spectra contain contributions from decay occurring at both "molecular" and "atomic" internuclear distances. We have observed a new interferenc
18.	Guo, JH, et al. (author) Resonant and nonresonant x-ray scattering spectra of some poly(phenylenevinylene)s 1998 In: JOURNAL OF CHEMICAL PHYSICS. - 0021-9606. ; 108:14, s. 5990-5996 Journal article (other academic/artistic)abstract The electronic structure of some poly(phenylenevinylene)s have been investigated by resonant and nonresonant x-ray inelastic scattering spectroscopies. The nonresonant as well as all resonant spectra for each polymer demonstrate benzene-like features, ind
19.	Hyvonen, R, et al. (author) Predicting long-term soil carbon storage from short-term information 1998 In: SOIL SCIENCE SOCIETY OF AMERICA JOURNAL. - : SOIL SCI SOC AMER. - 0361-5995. ; 62:4, s. 1000-1005 Journal article (other academic/artistic)abstract Changes in land use and in climate may induce changes in soil organic matter storage in different ecosystems, Predictions of future soil organic matter storage are based on extrapolations from shortterm observations. Certain errors in the extrapolation pr
20.	Komisopoulos, G, et al. (author) Comparison of dose-response relations of anal sphincter and anal canal regarding the radiation effects of faecal leakage and blood or phlegm in stools from prostate cancer radiotherapy 2006 In: RADIOTHERAPY AND ONCOLOGY. - 0167-8140. ; 81, s. S441-S442 Conference paper (other academic/artistic)
21.	Lindeman, E, et al. (author) Neuropathy with Cerebral Features Induced by Nitrous Oxide Abuse-A Case Report 2023 In: Toxics. - 2305-6304. ; 11:12 Journal article (other academic/artistic)
22.	Mavroidis, P., et al. (author) Dose-Response Relations for Anal Sphincter Regarding Fecal Leakage and Blood or Phlegm in Stools after Radiotherapy for Prostate Cancer Radiobiological Study of 65 Consecutive Patients 2005 In: Strahlenther Onkol. - 0179-7158. ; 181:5, s. 293-306 Journal article (peer-reviewed)abstract BACKGROUND: : The estimation of the parameters that describe the dose-response relations of anal sphincter regarding the clinical endpoints of fecal leakage and blood or phlegm in stools is important in the optimization of prostate cancer radiotherapy. Also, the validity of the relative seriality model for this clinical case needs to be examined by associating the clinical follow-up results with the predicted complication rates. PATIENTS AND METHODS: : In this study, 65 patients who received radiation therapy for clinically localized prostate adenocarcinoma are analyzed. The clinical treatment outcome and the three-dimensional dose distribution delivered to anal sphincter were available for each patient. A questionnaire was used for assessing the clinical bowel and urinary symptoms. A maximum likelihood fitting was performed to calculate the best estimates of the parameters used by the relative seriality model. The clinical utilization of the calculated parameters in predicting anal sphincter complication probabilities was illustrated by applying the best estimate of the parameters to a subset of the patient population. RESULTS: : The estimated values of the parameters for the two clinical endpoints are D (50) = 70.2 Gy, gamma = 1.22, s = 0.35 for fecal leakage and D (50) = 74.0 Gy, gamma = 0.75, s approximately 0 for blood or phlegm in stools. The standard deviations of the parameters were also calculated together with the confidence intervals of the dose-response curves. The analysis proved that the treatment outcome pattern of the patient material can suitably be reproduced by the relative seriality model (probability of finding a worse fit = 60.2%, the area under the receiver operating characteristic curve = 0.72 and 0.69 and chi(2)-test = 0.97 and 0.86, respectively). CONCLUSION: : Fecal leakage is characterized by a medium relative seriality whereas blood or phlegm in stools was found to have strong volume dependence (low relative seriality). Diminishing the biologically effective uniform dose to anal sphincter < 40-45 Gy may significantly reduce the risk of fecal leakage or blood or phlegm in stools for patients irradiated for prostate cancer.
23.	Paucar, M, et al. (author) Novel KCND3 mutation associated with paroxysmal motor exacerbations in spinocerebellar ataxia 19 2020 In: MOVEMENT DISORDERS. - 0885-3185. ; 35, s. S21-S22 Conference paper (other academic/artistic)
24.	Paucar, M, et al. (author) V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations 2021 In: Neurology. Genetics. - 2376-7839. ; 7:2, s. e567- Journal article (peer-reviewed)
25.	Piancastelli, MN, et al. (author) Bond-distance-dependent decay probability of the N 1s -> pi* core-excited state in N-2 2000 In: JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS. - : IOP PUBLISHING LTD. - 0953-4075. ; 33:9, s. 1819-1826 Journal article (peer-reviewed)abstract We report the observation of the unusually weak decay of the N 1s --> pi* core-excited N-2 molecule to the (B) over tilde (2)Sigma(u)(+) final state of N-2(+), which is only detectable in an experiment with high sensitivity. The resonant Auger spectra exh
26.	Rimondini, R, et al. (author) Persistent behavioral and autonomic supersensitivity to stress following prenatal stress exposure in rats 2003 In: Behavioural brain research. - : Elsevier BV. - 0166-4328. ; 140:1-2, s. 75-80 Journal article (peer-reviewed)
27.	Rääf, Christopher, et al. (author) Transfer of (137)Cs from Chernobyl debris and nuclear weapons fallout to different Swedish population groups. 2006 In: Science of the Total Environment. - : Elsevier BV. - 1879-1026 .- 0048-9697. ; 367:Feb 24, s. 324-340 Journal article (peer-reviewed)abstract Data from measurements on the body burden Of (CS)-C-134, Cs-137 and K-40 in various Swedish populations between 1959 and 2001 has been compiled into a national database. The compilation is a co-operation between the Departments of Radiation Physics in Malmo and Goteborg, the National Radiation Protection Authority (SSI) and the Swedish Defense Research Agency (FOI). In a previous study the effective ecological half time and the associated effective dose to various Swedish populations due to internal contamination of Cs-134 and Cs-137 have been assessed using the database. In this study values of human body burden have been combined with data on the local and regional ground deposition of fallout from nuclear weapons tests (only Cs-137) and Chernobyl debris (both Cs-134 and (CS)-C-137), which have enabled estimates of the radioecological transfer in the studied populations. The assessment of the database shows that the transfer of radiocesium from Chernobyl fallout to humans varies considerably between various populations in Sweden. In terms of committed effective dose over a 70 y period from internal contamination per unit activity deposition, the general (predominantly urban) Swedish population obtains 20-30 mu Sv/kBq m(-2). Four categories of populations exhibit higher radioecological transfer than the general population; i.) reindeer herders (similar to 700 mu Sv/kBq m(-2)), ii.) hunters in the counties dominated by forest vegetation (similar to 100 mu Sv/kBq m(-2)), iii.) rural non-farming populations living in sub-arctic areas (40-150 mu Sv/kBq m(-2)), and iv.) farmers (similar to 50 mu Sv/kBq m(-2)). Two important factors determine the aggregate transfer from ground deposition to man; i.) dietary habits (intakes of foodstuff originating from natural and semi-natural ecosystems), and ii.) inclination to follow the recommended food restriction by the authorities. The transfer to the general population is considerably lower (similar to a factor of 3) for the Chernobyl fallout than during the 1960s and 70s, which is partly explained by a higher awareness of the pathways of radiocaesium to man both by the public and by the regulating authorities, and by the time-pattern of the nuclear weapons fallout during the growth season in Sweden. (c) 2005 Elsevier B.V. All rights reserved.
28.	Saarinen, M, et al. (author) Correction To: TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP- 363856 2023 In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. - : Springer Science and Business Media LLC. - 1740-634X. ; 48:35, s. 846-846 Journal article (other academic/artistic)
29.	Saarinen, M, et al. (author) Pharmacological Characterization of Potent Human Trace Amine-Associated Receptor 1 (TAAR1) Agonists 2023 In: NEUROPSYCHOPHARMACOLOGY. - 0893-133X. ; 48, s. 391-391 Conference paper (other academic/artistic)
30.	Salek, P, et al. (author) Dynamical suppression of atomic peaks in resonant dissociative photoemission 2001 In: CHEMICAL PHYSICS LETTERS. - : ELSEVIER SCIENCE BV. - 0009-2614. ; 343:3-4, s. 332-338 Language: English Journal article (peer-reviewed)abstract Resonant excitation to the F1s-sigma* dissociative state in hydrogen fluoride gives a photoelectron spectrum where the spectator part contains strong atomic lines but a participator part where such lines are lacking. We demonstrate that this contrasting b
31.	Salek, P, et al. (author) Resonant x-ray Raman scattering involving avoided crossings in the final-state potential-energy curves - art. no. 062506 2000 In: PHYSICAL REVIEW A. - : AMERICAN PHYSICAL SOC. - 1050-2947. ; 6206:6, s. 2506- Journal article (peer-reviewed)abstract The role of avoided crossings for resonant x-ray Raman scattering is explored. The strong dependence of the electronic transition amplitudes on internuclear distance at avoided crossings causes new, and even anomalous, spectral features, and can bring abo
32.	Schmidt, DE, et al. (author) Correlation of thromboelastography and thrombin generation assays in warfarin-treated patients 2019 In: Thrombosis research. - : Elsevier BV. - 1879-2472 .- 0049-3848. ; 178, s. 34-40 Journal article (peer-reviewed)
33.	Schnell, R, et al. (author) 1.9 A structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis 2008 In: Acta crystallographica. Section F, Structural biology and crystallization communications. - 1744-3091. ; 64:Pt 12, s. 1096-1100 Journal article (peer-reviewed)
34.	Skeppholm, M, et al. (author) Effects of new oral anticoagulants on fibrin-network permeability and thrombin generation 2015 In: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. - 1538-7933. ; 13, s. 396-396 Conference paper (other academic/artistic)
35.	Slotte, Tanja, et al. (author) The Capsella rubella genome and the genomic consequences of rapid mating system evolution 2013 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:7, s. 831-U165 Journal article (peer-reviewed)abstract The shift from outcrossing to selfing is common in flowering plants(1,2), but the genomic consequences and the speed at which they emerge remain poorly understood. An excellent model for understanding the evolution of self fertilization is provided by Capsella rubella, which became self compatible <200,000 years ago. We report a C. rubella reference genome sequence and compare RNA expression and polymorphism patterns between C. rubella and its outcrossing progenitor Capsella grandiflora. We found a clear shift in the expression of genes associated with flowering phenotypes, similar to that seen in Arabidopsis, in which self fertilization evolved about 1 million years ago. Comparisons of the two Capsella species showed evidence of rapid genome-wide relaxation of purifying selection in C. rubella without a concomitant change in transposable element abundance. Overall we document that the transition to selfing may be typified by parallel shifts in gene expression, along with a measurable reduction of purifying selection.
36.	Stahlberg, D, et al. (author) Instant technetium 99m hexamethyl propylenamine oxime-labeled leukocyte scan compared with colonoscopy in early assessment of disease extent and activity in acute colitis 1996 In: Diseases of the colon and rectum. - 0012-3706. ; 39:10, s. 1146-1152 Journal article (peer-reviewed)
37.	Stahlberg, D, et al. (author) Leukocyte migration in acute colonic inflammatory bowel disease: comparison of histological assessment and Tc-99m-HMPAO labeled leukocyte scan 1997 In: The American journal of gastroenterology. - 0002-9270. ; 92:2, s. 283-288 Journal article (peer-reviewed)
38.	Sun, Hao, et al. (author) Engineering Tunable Ratiometric Dual Emission in Single Emitter-based Amorphous Systems 2024 In: Angewandte Chemie International Edition. - : WILEY-V C H VERLAG GMBH. - 1433-7851 .- 1521-3773. Journal article (peer-reviewed)abstract Molecular emitters with multi-emissive properties are in high demand in numerous fields, while these properties basically depend on specific molecular conformation and packing. For amorphous systems, special molecular arrangement is unnecessary, but it remains challenging to achieve such luminescent behaviors. Herein, we present a general strategy that takes advantage of molecular rigidity and S1-T1 energy gap balance for emitter design, which enables fluorescence-phosphorescence dual-emission properties in various solid forms, whether crystalline or amorphous. Subsequently, the amorphism of the emitters based polymethyl methacrylate films endowed an in situ regulation of the dual-emissive characteristics. With the ratiometric regulation of phosphorescence by external stimuli and stable fluorescence as internal reference, highly controllable luminescent color tuning (yellow to blue including white emission) was achieved. There properties together with a persistent luminous behavior is of benefit for an irreplaceable set of optical information combination, featuring an ultrahigh-security anti-counterfeiting ability. Our research introduces a concept of eliminating the crystal-form and molecular-conformational dependence of complex luminescent properties through emitter molecular design. This has profound implications for the development of functional materials. A molecular structural strategy enabling single emitter based dual-emission properties in various solid forms is presented. The developed amorphous films endow in situ regulation of the dual-emissive characteristics to show highly controllable multiple luminescent color tuning (yellow to blue including white emission), which benefits to the construction of an irreplaceable set of optical information combination.image
39.	Svenningson, P, et al. (author) TAAR1 Dependent and Independent Actions of the Potential Antipsychotic and Dual TAAR1/5HT1A Receptor Agonist SEP-383856 2022 In: NEUROPSYCHOPHARMACOLOGY. - 0893-133X. ; 47, s. 391-391 Conference paper (other academic/artistic)
40.	Torkvist, L, et al. (author) Low molecular weight heparin as adjuvant therapy in active ulcerative colitis 1999 In: Alimentary pharmacology & therapeutics. - : Wiley. - 0269-2813. ; 13:10, s. 1323-1328 Journal article (peer-reviewed)
41.	Torkvist, L, et al. (author) Low molecular weight heparin as adjuvant therapy in ulcerative colitis. 1998 In: GASTROENTEROLOGY. - 0016-5085. ; 114:4, s. A1100-A1101 Conference paper (other academic/artistic)
42.	Zachrisson, OCG, et al. (author) No evident neuronal damage after electroconvulsive therapy 2000 In: Psychiatry research. - 0165-1781. ; 96:2, s. 157-165 Journal article (peer-reviewed)
43.	Zenlander, R, et al. (author) Markers of neutrophil extracellular traps are elevated in patients with Child-Pugh B and C liver cirrhosis or large hepatocellular carcinomas 2021 In: JOURNAL OF HEPATOLOGY. - 0168-8278. ; 75, s. S339-S339 Conference paper (other academic/artistic)
44.	Zenlander, R, et al. (author) Neutrophil extracellular traps in patients with liver cirrhosis and hepatocellular carcinoma 2021 In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 11:1, s. 18025- Journal article (peer-reviewed)abstract Neutrophil extracellular traps (NETs) are web-like structures consisting of DNA, histones and granule proteins, released from neutrophils in thrombus formation, inflammation, and cancer. We asked if plasma levels of the NET markers myeloperoxidase (MPO)-DNA and citrullinated histone H3 (H3Cit)-DNA, are elevated in liver cirrhosis and hepatocellular carcinoma (HCC) and if the levels correlate with clinical parameters. MPO-DNA, H3Cit-DNA, and thrombin–antithrombin (TAT) complex, as a marker of coagulation activity, were measured using ELISA in plasma from 82 patients with HCC, 95 patients with cirrhosis and 50 healthy controls. Correlations were made to clinical parameters and laboratory data and patients were followed for a median of 22.5 months regarding thrombosis development. H3Cit-DNA was significantly (p < 0.01) elevated in plasma from cirrhosis (66.4 ng/mL) and HCC (63.8 ng/mL) patients compared to healthy controls (31.8 ng/mL). TAT levels showed similar pattern (3.1, 3.7, and 0.0 µg/mL respectively, p < 0.01). MPO-DNA was significantly (p < 0.01) elevated in cirrhosis patients (0.53 O.D.) as compared to controls (0.33 O.D.). Levels of MPO-DNA and H3Cit-DNA correlated positively with Child–Pugh and MELD score. TAT was increased in all Child–Pugh and MELD groups. In multivariable logistic regression, Child B and C liver cirrhosis were independent predictors of elevated H3Cit-DNA in plasma. Levels of MPO-DNA and H3Cit-DNA were similar in patients with or without history of thrombosis, or thrombus formation during follow-up. In conclusion, plasma markers of NET formation are elevated in liver cirrhosis and correlate to the degree of liver dysfunction in patients with liver cirrhosis and/or HCC. The presence of HCC did not further increase the plasma levels of NET markers as compared to patients with cirrhosis only.

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