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1.	Bjorkegren, JLM, et al. (author) PLASMA CHOLESTEROL-INDUCED REGRESSION OF EARLY, MATURE, AND ADVANCED ATHEROSCLEROSIS 2014 In: ATHEROSCLEROSIS. - 0021-9150. ; 235:2, s. E29-E29 Conference paper (other academic/artistic)
2.	Braenne, I, et al. (author) Prediction of Causal Candidate Genes in Coronary Artery Disease Loci 2015 In: Arteriosclerosis, thrombosis, and vascular biology. - 1524-4636. ; 35:10, s. 2207-2217 Journal article (peer-reviewed)
3.	Grahn, A, et al. (author) Genomic profile - a possible diagnostic and prognostic marker in upper tract urothelial carcinoma 2022 In: BJU international. - : Wiley. - 1464-410X .- 1464-4096. ; 130:1, s. 92-101 Journal article (peer-reviewed)
4.	Haitjema, S, et al. (author) Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization 2017 In: Circulation. Cardiovascular genetics. - 1942-3268. ; 10:2 Journal article (peer-reviewed)
5.	Lempiainen, H, et al. (author) Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets 2018 In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8:1, s. 3434- Journal article (peer-reviewed)abstract Genome-wide association studies (GWAS) have identified over two hundred chromosomal loci that modulate risk of coronary artery disease (CAD). The genes affected by variants at these loci are largely unknown and an untapped resource to improve our understanding of CAD pathophysiology and identify potential therapeutic targets. Here, we prioritized 68 genes as the most likely causal genes at genome-wide significant loci identified by GWAS of CAD and examined their regulatory roles in 286 metabolic and vascular tissue gene-protein sub-networks (“modules”). The modules and genes within were scored for CAD druggability potential. The scoring enriched for targets of cardiometabolic drugs currently in clinical use and in-depth analysis of the top-scoring modules validated established and revealed novel target tissues, biological processes, and druggable targets. This study provides an unprecedented resource of tissue-defined gene–protein interactions directly affected by genetic variance in CAD risk loci.
6.	Meddens, C, et al. (author) Systematic Analyses of Chromatin Interactions at IBD-associated Loci Identify IL10RA and ATG9A as Novel Candidate Genes 2017 In: INFLAMMATORY BOWEL DISEASES. - 1078-0998. ; 23, s. S98-S98 Conference paper (other academic/artistic)
7.	Meddens, CA, et al. (author) Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease 2016 In: Genome biology. - : Springer Science and Business Media LLC. - 1474-760X. ; 17:1, s. 247- Journal article (peer-reviewed)
8.	Pasterkamp, G, et al. (author) Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype 2016 In: Arteriosclerosis, thrombosis, and vascular biology. - 1524-4636. ; 36:6, s. 1240- Journal article (peer-reviewed)
9.	Qi, JL, et al. (author) kruX: matrix-based non-parametric eQTL discovery 2014 In: BMC bioinformatics. - : Springer Science and Business Media LLC. - 1471-2105. ; 15, s. 11- Journal article (peer-reviewed)
10.	Rossignoli, A, et al. (author) Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration 2017 In: Arteriosclerosis, thrombosis, and vascular biology. - 1524-4636. ; 37:3, s. 534- Journal article (peer-reviewed)
11.	Siemelink, MA, et al. (author) Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions 2018 In: Circulation. Genomic and precision medicine. - 2574-8300. ; 11:9, s. e002030- Journal article (peer-reviewed)
12.	Talukdar, HA, et al. (author) Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease 2016 In: Cell systems. - : Elsevier BV. - 2405-4712. ; 2:3, s. 196-208 Journal article (peer-reviewed)
13.	van der Laan, SW, et al. (author) Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques 2018 In: Circulation. Genomic and precision medicine. - 2574-8300. ; 11:9, s. e002115- Journal article (peer-reviewed)
14.	van der Laan, SW, et al. (author) Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study 2015 In: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 239:2, s. 528-538 Journal article (peer-reviewed)
15.	Vilne, B, et al. (author) Evidence That Loss of Nuclear-Encoded Mitochondrial Gene Activity in the Arterial Wall Relates to Atherosclerotic Lesion Development 2016 In: CIRCULATION. - 0009-7322. ; 134 Conference paper (other academic/artistic)
16.	Vilne, B, et al. (author) Network analysis reveals a causal role of mitochondrial gene activity in atherosclerotic lesion formation 2017 In: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 267, s. 39-48 Journal article (peer-reviewed)

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Result 1-16 of 16

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Type of publication: journal article (13); conference paper (3)

Type of content: peer-reviewed (13); other academic/artistic (3)

Author/Editor: Bjorkegren, JLM (11); Asselbergs, FW (7); Michoel, T (7); van der Laan, SW (6); Pasterkamp, G (6); Schunkert, H. (6); show more...; den Ruijter, HM (5); Mokry, M (5); Erdmann, J. (4); Samani, NJ (4); Franzen, O (3); Dichgans, M (2); Civelek, M (2); Malik, R (2); Bjorkegren, J (2); Kessler, T (2); Webb, TR (2); Ruusalepp, A (2); Lusis, AJ (2); Tragante, V (2); de Bakker, PIW (2); de Borst, GJ (2); Yang, X. (1); Yla-Herttuala, S (1); Mueller, S (1); Bis, JC (1); Jukema, JW (1); Hedin, U (1); Paulsson-Berne, G (1); Melander, O. (1); Hamsten, A (1); Cuppen, E (1); Cheng, C (1); Perisic, L. (1); Waltenberger, J (1); Johnson, AD (1); Heijmans, BT (1); Ivert, T (1); Goel, A. (1); Readhead, B (1); Giannarelli, C (1); Tham, E. (1); Kyriakou, T (1); Watkins, H (1); Hagg, S (1); Brehmer, M (1); Moessinger, C (1); Kovacic, JC (1); Zhao, YQ (1); Tregouet, DA (1); show less...

University: Karolinska Institutet (16)

Language: English (16)

Research subject (UKÄ/SCB): Natural sciences (1); Medical and Health Sciences (1)

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