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  • Murray, Christopher J. L., et al. (author)
  • Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
  • 2018
  • In: The Lancet. - 1474-547X .- 0140-6736. ; 392:10159, s. 1995-2051
  • Journal article (peer-reviewed)abstract
    • Background: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of population and fertility, although useful, have not been produced with transparent and replicable methods and do not use standardised estimates of mortality. We present single-calendar year and single-year of age estimates of fertility and population by sex with standardised and replicable methods. Methods: We estimated population in 195 locations by single year of age and single calendar year from 1950 to 2017 with standardised and replicable methods. We based the estimates on the demographic balancing equation, with inputs of fertility, mortality, population, and migration data. Fertility data came from 7817 location-years of vital registration data, 429 surveys reporting complete birth histories, and 977 surveys and censuses reporting summary birth histories. We estimated age-specific fertility rates (ASFRs; the annual number of livebirths to women of a specified age group per 1000 women in that age group) by use of spatiotemporal Gaussian process regression and used the ASFRs to estimate total fertility rates (TFRs; the average number of children a woman would bear if she survived through the end of the reproductive age span [age 10–54 years] and experienced at each age a particular set of ASFRs observed in the year of interest). Because of sparse data, fertility at ages 10–14 years and 50–54 years was estimated from data on fertility in women aged 15–19 years and 45–49 years, through use of linear regression. Age-specific mortality data came from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 estimates. Data on population came from 1257 censuses and 761 population registry location-years and were adjusted for underenumeration and age misreporting with standard demographic methods. Migration was estimated with the GBD Bayesian demographic balancing model, after incorporating information about refugee migration into the model prior. Final population estimates used the cohort-component method of population projection, with inputs of fertility, mortality, and migration data. Population uncertainty was estimated by use of out-of-sample predictive validity testing. With these data, we estimated the trends in population by age and sex and in fertility by age between 1950 and 2017 in 195 countries and territories. Findings: From 1950 to 2017, TFRs decreased by 49·4% (95% uncertainty interval [UI] 46·4–52·0). The TFR decreased from 4·7 livebirths (4·5–4·9) to 2·4 livebirths (2·2–2·5), and the ASFR of mothers aged 10–19 years decreased from 37 livebirths (34–40) to 22 livebirths (19–24) per 1000 women. Despite reductions in the TFR, the global population has been increasing by an average of 83·8 million people per year since 1985. The global population increased by 197·2% (193·3–200·8) since 1950, from 2·6 billion (2·5–2·6) to 7·6 billion (7·4–7·9) people in 2017; much of this increase was in the proportion of the global population in south Asia and sub-Saharan Africa. The global annual rate of population growth increased between 1950 and 1964, when it peaked at 2·0%; this rate then remained nearly constant until 1970 and then decreased to 1·1% in 2017. Population growth rates in the southeast Asia, east Asia, and Oceania GBD super-region decreased from 2·5% in 1963 to 0·7% in 2017, whereas in sub-Saharan Africa, population growth rates were almost at the highest reported levels ever in 2017, when they were at 2·7%. The global average age increased from 26·6 years in 1950 to 32·1 years in 2017, and the proportion of the population that is of working age (age 15–64 years) increased from 59·9% to 65·3%. At the national level, the TFR decreased in all countries and territories between 1950 and 2017; in 2017, TFRs ranged from a low of 1·0 livebirths (95% UI 0·9–1·2) in Cyprus to a high of 7·1 livebirths (6·8–7·4) in Niger. The TFR under age 25 years (TFU25; number of livebirths expected by age 25 years for a hypothetical woman who survived the age group and was exposed to current ASFRs) in 2017 ranged from 0·08 livebirths (0·07–0·09) in South Korea to 2·4 livebirths (2·2–2·6) in Niger, and the TFR over age 30 years (TFO30; number of livebirths expected for a hypothetical woman ageing from 30 to 54 years who survived the age group and was exposed to current ASFRs) ranged from a low of 0·3 livebirths (0·3–0·4) in Puerto Rico to a high of 3·1 livebirths (3·0–3·2) in Niger. TFO30 was higher than TFU25 in 145 countries and territories in 2017. 33 countries had a negative population growth rate from 2010 to 2017, most of which were located in central, eastern, and western Europe, whereas population growth rates of more than 2·0% were seen in 33 of 46 countries in sub-Saharan Africa. In 2017, less than 65% of the national population was of working age in 12 of 34 high-income countries, and less than 50% of the national population was of working age in Mali, Chad, and Niger. Interpretation: Population trends create demographic dividends and headwinds (ie, economic benefits and detriments) that affect national economies and determine national planning needs. Although TFRs are decreasing, the global population continues to grow as mortality declines, with diverse patterns at the national level and across age groups. To our knowledge, this is the first study to provide transparent and replicable estimates of population and fertility, which can be used to inform decision making and to monitor progress. Funding: Bill & Melinda Gates Foundation.
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  • Abbafati, Cristiana, et al. (author)
  • 2020
  • Journal article (peer-reviewed)
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  • Abate, Ebba, et al. (author)
  • Effects of albendazole treatment on the clinical outcome and immunological responses in patients with helminth infection and pulmonary tuberculosis : a randomized clinical trial
  • 2013
  • Other publication (other academic/artistic)abstract
    • Background: The impact of helminth infection on the host immune response to tuberculosis (TB) has been characterized in experimental models but less so in the clinical setting. The objective of this study was to investigate the impact of deworming on the clinical outcome and cell mediated immune response in active TB.Methods: Newly diagnosed pulmonary TB patients in Gondar, Ethiopia were examined for helminth infection. Helminth-positive TB patients (W+/TB) were randomized to albendazole (400mg X III per os) or placebo. The primary outcome was change in TB-score after 2 months, and secondary outcomes were sputum smear conversion at the 2nd month, and changes in chest x-ray pattern, CD4+ T-cell count, eosinophil count, IgE-levels and immunological responses after 3 months. In a subset of W+/TB, W-/TB patients and healthy controls, flow cytometry and ELISPOT assays were used to characterize the regulatory T-cell population (Tregs) and the frequency of PPD- stimulated IFN-γ, IL-5 and IL-10 producing peripheral blood mononuclear cells (PBMCs).Results: A total of 140 helminth co-infected TB patients were included with an HIV coinfection rate of 22.8 %. Following albendazole treatment of the W+/TB patients, there was a significant decrease in helminth infection compared to placebo (8% (4/49) vs. 48 % (22/46), p<0.001). No significant effect was observed for albendazole compared to placebo on the primary outcome as evaluated by the TB-score (5.6 ±2.87 vs. 5.87 ±2.54, p=0.59). Eosinophil counts decreased significantly in the albendazole group. In a subgroup analysis of helminthnegative patients following albendazole treatment versus placebo, the albendazole group showed a trend for lower levels of IL-10 producing cells at month three (p=0.08). At baseline, W+/TB patients had a significantly higher mean level of Tregs (% Tregs/CD4+) compared to W-/TB patients and helminth-positive community controls. Additionally, the frequency of IFN-γ, IL-5 and spontaneous IL-10 levels was increased in helminth-positive compared to helminth-negative TB patients.Conclusions: No significant effects on the clinical outcome as measured with the TB-score was detected after albendazole treatment of helminth-positive TB patients compared to placebo. However, significant changes were observed in specific immunological responses such as reduced eosinophil counts and a trend towards lower levels of IL-10 producing cells. At baseline, helminth co-infected TB patients exhibited an increased Treg response as well as an increased IL-5 and spontaneous IL-10 production.
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  • Abate, Ebba, et al. (author)
  • Impact of helminth infection on the clinical presentation 1 of pulmonary tuberculosis
  • 2013
  • Other publication (other academic/artistic)abstract
    • Background: The effects of helminth infection on chronic infectious diseases such as HIV and tuberculosis (TB) merit further characterization. Thus, we assessed the baseline clinical characteristics of helminth infection in patients with active TB in a high endemic area.Methodology: Consecutive, newly diagnosed TB patients were recruited from three health institutions in the north Gondar administrative zone, Ethiopia. Structured questionnaires were used to collect socio-demographic and clinical characteristics. Additionally, the TB score, mid upper arm circumference, body mass index (BMI), BCG vaccination status, stool and sputum microscopy as well as HIV serology and CD4+T cells counts were evaluated.Results: A total of 377 pulmonary TB patients were included in the study. The helminth co infection rate was 33% (123/377) and the most prevalent parasite was Ascaris lumbricoides (53%, 65/123). The HIV co-infection rate was 29% (110/377). Seventy percent (77/110) of the HIV co-infected patients were on anti- retroviral therapy at the time of TB diagnosis. Helminth infection was more prevalent in HIV-negative TB patients compared to HIV-positive TB patients (p=0.025). Smoking and walking bare foot were independently associated to helminth infection in TB patients after adjusting for the influence of HIV. Other than increased eosinophilia, no other significant differences were observed between helminth positive and helminth negative TB patients in the clinical presentation including the TB score, CD4+T-cells, BMI or bacterial load.Conclusion: The clinical presentation of active pulmonary tuberculosis was not affected by helminth infection. Helminth infection was less frequent among HIV-positive TB patients and this finding merits further investigation.
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  • Abate, Ebba, et al. (author)
  • The Impact of Asymptomatic Helminth Co-Infection in Patients with Newly Diagnosed Tuberculosis in North-West Ethiopia
  • 2012
  • In: PLOS ONE. - : Public Library of Science. - 1932-6203. ; 7:8
  • Journal article (peer-reviewed)abstract
    • Background: Areas endemic of helminth infection, tuberculosis (TB) and HIV are to a large extent overlapping. The aim of this study was to assess the impact of asymptomatic helminth infection on the immunological response among TB patients with and without HIV, their house hold contacts and community controls. less thanbrgreater than less thanbrgreater thanMethodology: Consecutive smear positive TB patients (n = 112), their household contacts (n = 71) and community controls (n = 112) were recruited in Gondar town, Ethiopia. Stool microscopy, HIV serology, serum IgE level, eosinophil and CD4 counts were performed and tuberculosis patients were followed up for 3 months after initiation of anti-TB treatment. less thanbrgreater than less thanbrgreater thanResults: Helminth co-infection rate was 29% in TB patients and 21% in both community control and household contacts (p = 0.3) where Ascaris lumbricoides was the most prevalent parasite. In TB patients the seroprevalence of HIV was 47% (53/112). Eosinophilia and elevated IgE level were significantly associated with asymptomatic helminth infection. During TB treatment, the worm infection rate of HIV+/TB patients declined from 31% (10/32) at week 0 to 9% (3/32) at week 2 of TB treatment, whereas HIV2/TB patients showed no change from baseline to week 2, 29% (13/45) vs. 22.2% (10/45). This trend was stable at week 8 and 12 as well. less thanbrgreater than less thanbrgreater thanConclusion: One third of smear positive TB patients were infected with helminths. Eosinophilia and elevated IgE level correlated with asymptomatic worm infection, indicating an effect on host immunity. The rate of worm infection declined during TB treatment in HIV+/TB co-infected patients whereas no decline was seen in HIV2/TB group.
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  • Assefa, Getachew, et al. (author)
  • Environmental assessment of building properties — Where natural and social sciences meet : the case of EcoEffect
  • 2007
  • In: Building and Environment. - : Elsevier BV. - 0360-1323 .- 1873-684X. ; 42:3, s. 1458-1464
  • Journal article (peer-reviewed)abstract
    • The EcoEffect method of assessing external and internal impacts of building properties is briefly described. The external impacts of manufacturing and transport of the building materials, the generation of power and heat consumed during the operation phase are assessed using life-cycle methodology. Emissions and waste; natural resource depletion and toxic substances in building materials are accounted for. Here methodologies from natural sciences are employed. The internal impacts involve the assessment of the risk for discomfort and ill-being due to features and properties of both the indoor environment and outdoor environment within the boundary of the building properties. This risk is calculated based on data and information from questionnaires; measurements and inspection where methodologies mainly from social sciences are used. Life-cycle costs covering investment and utilities costs as well as maintenance costs summed up over the lifetime of the building are also calculated.The result presentation offers extensive layers of diagrams and data tables ranging from an aggregated diagram of environmental efficiency to quantitative indicators of different aspects and factors. Environmental efficiency provides a relative measure of the internal quality of a building property in relation to its external impact vis-à-vis its performance relative to other building properties.
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  • Assefa, Getachew, et al. (author)
  • Kompostering eller förbränning av hushållsavfall i Stockholm : En systemstudie av effekter på miljö, energi och ekonomi
  • 2001
  • Reports (other academic/artistic)abstract
    • En systemanalys som utvärderar potentiella effekter på miljön, energiomsättning och ekonomi har genomförts där storskalig kompostering jämförts med förbränning. Studien har utförts på uppdrag av Birka Värme och är tänkt som en jämförelse av olika former av kapacitetsökning för behandling av avfall i Stockholmsområdet. Förebilder för behandlingsprocesserna är avfallsförbränningsanläggningen Högdalenverket som drivs av Birka Energi och en planerad storskalig komposteringsanläggning i Stora Vika i Rondecos regi. Avfallet samlas in från Stockholm med närområden. Avfallet består till större delen av lättnedbrytbart organiskt avfall och slam från reningsverk. Även rötning har jämförts där en mindre del av totala avfallet, motsvarande ledig kapacitet i rötningsanläggningen, behandlas.Studien visar att det ur de flesta av de betraktade aspekterna är fördelaktigare att förbränna avfallet än att kompostera det. Detta beror på miljöpåverkan (övergödning och höga tungmetallhalter) i hanteringen av kompostpelletsen och inverkan av att förlorad fjärrvärmeproduktion vid kompostering måste ersättas.Kompostering är att föredra ur klimatsynpunkt då dess bidrag till global uppvärmning (växthuseffekten) är totalt sett något lägre än för förbränning. Det beror till största del på att koldioxid från förbränning av plast som finns i avfallet frigörs vid avfallsförbränningen. Skillnaden är dock inom felmarginalen och resultatet bör ej tas för självklart.För den potentiella miljöeffekten försurning är det dött lopp mellan kompostering och förbränning. Förbränningen av avfall ger visserligen högre försurande utsläpp än komposteringen men när hänsyn tas till att förlorad fjärrvärme måste ersättas vid kompostering och att det går åt mer elektricitet vid kompostering, elektricitet som antas framställas från förbränning av kol, jämnar resultatet ut sig.Det finns en hel del svagheter i analysen, bland annat är det inte fullständigt klarlagt vilka materialbalanser som råder i komposteringsprocessen. Även för spridningen av kompostpelletsen råder stora osäkerheter. I dessa fall har antaganden gjorts men det är viktigt att i den fortsatta granskningen använda tillförlitligare data.
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  • Assefa, Getachew, et al. (author)
  • Life Cycle Assessment of Thermal Treatment Technologies : An environmental and financial systems analysis of gasification, incineration and landfilling of waste
  • 2002
  • Reports (other academic/artistic)abstract
    • A technology which is currently developed by researchers at KTH is catalytic combustion which is one component of a gasification system. Instead of performing the combustion in the gas turbine by a flame, a catalyst is used. When the development of a new technology (as catalytic combustion) reaches a certain step where it is possible to quantify material-, energy- and capital flows, the prerequisites for performing a systems analysis is at hand. The systems analysis can be used to expand the know-how about the potential advantages of the catalytic combustion technology by highlighting its function as a component of a larger system. In this way it may be possible to point out weak points which have to be investigated more, but also strong points to emphasise the importance of further development.The aim of this project was to assess the energy turnover as well as the potential environmental impacts and economic costs of thermal treatment technologies in general and catalytic combustion in particular. By using a holistic assessment of the advantages and disadvantages of catalytic combustion of waste it was possible to identify the strengths and weaknesses of the technology under different conditions. Following different treatment scenarios have been studied: (1) Gasification with catalytic combustion, (2) Gasification with flame combustion, (3) Incineration with energy recovery and (4) Landfilling with gas collection. In the study compensatory district heating is produced by combustion of biofuel. The power used for running the processes in the scenarios is supplied by the waste-to-energy technologies themselves while compensatory power is assumed to be produced from natural gas. The emissions from the system studied were classified and characterised using methodology from Life Cycle Assessment into the following environmental impact categories: Global Warming Potential (also called the green house effect), Acidification Potential, Eutrophication Potential and finally Formation of Photochemical Oxidants.It is obvious that a decreased use of landfilling in favour of an increased energy recovery from waste is positive from all considered impact categories. Gasification with energy recovery in a combi cycle using catalytic combustion in the gas turbine is the most competitive technology from primarily an environmental point of view. The financial costs are however a bit higher than for incineration with energy recovery. This conclusion depends, however, on the assumption that the gasification and catalyst technologies work as the researchers presume and that the fuel is of high quality. For this, the pelletising unit is vital in the technology chain.A comparison of the catalytic combustion and the flame combustion shows that all impact categories except acidification, eutrophication and photochemical oxidants remain the same. The gasification process is identical between the two alternatives; it is just the combustion technology in the gas turbine that is different. This explains why the fuel consumption and the financial costs are not changed (a minor extra investment is made for the catalyst but is not noticeable in comparison to the total impact). Emissions of greenhouse gases are also identical. For the other impact categories there are differences for several of the emissions involved in the impact assessment but NOX is clearly the dominating one.Gasification with catalytic combustion is competitive to incineration. The small difference for eutrophication is within the error margin and is strongly dependent on the reduction of NOX in the incineration plant. The explanation to this result is that a combi cycle in combination with natural gas as the alternative power generation is a better system solution than incineration with biofuel as compensatory fuel. Financial costs are somewhat higher than for incineration but could also claimed to be within the error margin since the inventory of costs are more uncertain due to the fact that there is no plant with gasification and catalytic combustion in operation.
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  • Assefa, Getachew, 1972- (author)
  • On sustainability assessment of technical systems : experience from systems analysis with the ORWARE and ecoeffect tools
  • 2005
  • Doctoral thesis (other academic/artistic)abstract
    • Engineering research and development work is undergoing a reorientation from focusing on specific parts of different systems to a broader perspective of systems level, albeit at a slower pace. This reorientation should be further developed and enhanced with the aim of organizing and structuring our technical systems in meeting sustainability requirements in face of global ecological threats that have far-reaching social and economic implications, which can no longer be captured using conventional approach of research. Until a list of universally acceptable, clear, and measurable indicators of sustainable development is developed, the work with sustainability metrics should continue to evolve as a relative measure of ecological, economic, and social performance of human activities in general, and technical systems in particular. This work can be done by comparing the relative performance of alternative technologies of providing the same well-defined function or service; or by characterizing technologies that enjoy different levels of societal priorities using relevant performance indicators. In both cases, concepts and methods of industrial ecology play a vital role. This thesis is about the development and application of a systematic approach for the assessment of the performance of technical systems from the perspective of systems analysis, sustainability, sustainability assessment, and industrial ecology. The systematic approach developed and characterized in this thesis advocates for a simultaneous assessment of the ecological, economic, and social dimensions of performance of technologies in avoiding sub-optimization and problem shifting between dimensions. It gives a holistic picture by taking a life cycle perspective of all important aspects. The systematic assessment of technical systems provides an even-handed assessment resulting in a cumulative knowledge. A modular structure of the approach makes it flexible enough in terms of comparing a number of alternatives at the same time, and carrying out the assessment of the three dimensions independently. It should give way to transparent system where the level of quality of input data can be comprehended. The assessment approach should focus on a selected number of key input data, tested calculation procedures, and comprehensible result presentation. The challenge in developing and applying this approach is the complexity of method integration and information processing. The different parts to be included in the same platform come in with additional uncertainties hampering result interpretations. The hitherto tendency of promoting disciplinary lines will continue to challenge further developments of such interdisciplinary approaches. The thesis draws on the experience from ORWARE, a Swedish technology assessment tool applied in the assessment of waste management systems and energy systems; and from the EcoEffect tool used in the assessment of building properties; all assessed as components of a larger system. The thesis underlines the importance of sustainability considerations beginning from the research and development phase of technical systems. The core message of this thesis is that technical systems should be researched as indivisible parts of a complex whole that includes society and the natural environment. Results from such researches can then be transformed into design codes and specifications for use in the research and development, planning and structuring, and implementation and management of technical systems.
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  • Assefa, Getachew, et al. (author)
  • ORWARE : an aid to Environmental Technology Chain Assessment
  • 2005
  • In: Journal of Cleaner Production. - : Elsevier BV. - 0959-6526 .- 1879-1786. ; 13:3, s. 265-274
  • Journal article (peer-reviewed)abstract
    • This article discusses the ORWARE tool, a model originally developed for environmental systems analysis of waste management systems, and shows its prospect as a tool for environmental technology chain assessment. Different concepts of technology assessment are presented to put ORWARE into context in the discussion that has been going for more than two decades since the establishment of the US Congressional Office of Technology Assessment (OTA). An even-handed assessment is important in different ways such as reproducibility, reliability, credibility, etc. Conventional technology assessment (TA) relied on the judgements and intuition of the assessors. A computer-based tool such as ORWARE provides a basis for transparency and a structured management of input and output data that cover ecological and economic parameters. This permits consistent and coherent technology assessments. Using quantitative analysis as in ORWARE makes comparison and addition of values across chain of technologies easier. We illustrate the application of the model in environmental technology chain assessment through a study of alternative technical systems linking waste management to vehicle fuel production and use. The principles of material and substance flow modelling, life cycle perspective, and graphical modelling featured in ORWARE offer a generic structure for environmentally focused TA of chains and networks of technical processes.
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  • Assefa, Getachew, et al. (author)
  • Quality versus impact : Comparing the environmental efficiency of building properties using the EcoEffect tool
  • 2010
  • In: Building and Environment. - : Elsevier BV. - 0360-1323 .- 1873-684X. ; 45:5, s. 1095-1103
  • Journal article (peer-reviewed)abstract
    • There are tools that are developed for the assessment of the environmental impact of buildings (e.g. ATHENA). Other tools dealing with the indoor and outdoor environmental quality of building properties (referred to as real estates in other literature) are also available (e.g. GBTool). A platform where both the aspects of quality and impact are presented in an integrated fashion are few. The aim of this contribution is to present how the performance of different building properties can be assessed and compared using the concept of environmental efficiency in a Swedish assessment tool called EcoEffect. It presents the quality dimension in the form of users' satisfaction covering indoor and outdoor performance features against the weighted environmental impact covering global and local impacts. The indoor and outdoor values are collected using questionnaires combined with inspection and some measurements. Life cycle methodology is behind the calculation of the weighted external environmental impact. A case study is presented to show the application of EcoEffect using a comparative assessment of Lindas and a Reference property. The results show that Lindas block is better in internal environment quality than the Reference property. It performs slightly worse than the Reference property in the external environmental impact due to emissions and waste from energy and material use. The approach of integrated presentation of quality and impact as in EcoEffect provides with the opportunity of uncovering issues problem shifting and sub-optimisation. This avoids undesirable situations where the indoor quality is improved through measures that result in higher external environmental impact.
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  • Assefa, Getachew, et al. (author)
  • Social Impact Assessment within Life Cycle Technology Assessment
  • 2004
  • In: 4th SETAC World Congress.
  • Conference paper (peer-reviewed)abstract
    • Life cycle technology assessment provides a conceptual structure for different ecological, economic and social impact assessment (SIA) tools for acting together in determining the importance, size, or value of ecological, economic and social impacts of technology - doing and making things with materials and energy. In compatibly incorporating SIA with Material /Substance Flow Analysis, Life Cycle Assessment and Life Cycle Costing, different views of SIA are studied. An important difference between this exercise and conventional SIAs is that in the former case, there is no official plan or intention of implementing the technology in a specific time and place. This poses operational difficulty due to the poor knowledge about the community that will be affected by the technology in question. Besides, compatibility with LCA adds complexity associated with a requirement for the SIA to account for a number of communities associated with each portion of the life cycle. Thorough analysis of the opportunities and challenges involved led to the use of zooming analogy. Based on this analogy, in the absence of knowledge of detailed spatial and temporal coordinates of a specific community that will be affected by the technology, a reasonable level of zooming out is done. This enables identification and characterization of the most important social impact variables for the given technology in the zoomed out area ( e.g. say a country or region of a country). As an illustration, one variable from each of five categories of SIA variables will be used to characterize the social impacts of energy technologies in small municipalities in Sweden. These categories are population impacts; community and institutional arrangements; communities in transition; individual and family impacts; and community infrastructure needs. The knowledge from damage-based weighting of environmental impact categories using concepts such as Disability Adjusted Life Years (DALY) will be tested in characterizing the variables.
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  • Assefa, Getachew, et al. (author)
  • Social sustainability and social acceptance in technology assessment : a case study on energy technologies
  • 2007
  • In: Technology in society. - : Elsevier BV. - 0160-791X .- 1879-3274. ; 29:1, s. 63-78
  • Journal article (peer-reviewed)abstract
    • This paper discusses an approach for assessing indicators for the social sustainability of technical systems developed within a Swedish technology assessment tool called ORWARE. Social sustainability is approached from the perspective of one of its ingredients, namely social acceptance. The research takes the form of a case study on energy technologies conducted in the municipality of Kil in west central Sweden. Three indicators—knowledge, perception, and fear associated with four chains of energy technologies—are assessed using a questionnaire. The questionnaire results indicate that respondents have such a low level of information and knowledge about new energy technologies that they are unable to discriminately rank them. This was found to hamper participation in discussions and decision making about technologies for which public funds would be spent. The importance of assessing social indicators by engaging members of society is discussed, and an assessment approach is developed. The need to present results together with ecological and economic indicators is emphasised in order to avoid suboptimization.
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  • Assefa, Getachew (author)
  • Systems analysis of technology chains for energy recovery from waste
  • 2006
  • In: WMSCI 2006. - ORLANDO : INT INST INFORMATICS & SYSTEMICS. - 9789806560727 ; , s. 183-188
  • Conference paper (peer-reviewed)abstract
    • This contribution is based on the result of a project entitled "Systems Analysis: Energy Recovery from waste, catalytic combustion in comparison with fuel cells and incineration" is financed by The Swedish National Energy Administration. The aim of the project was to assess the energy turnover as well as the potential environmental impacts of biomass/waste-to-energy technologies. Four technology scenarios are be studied: (1) Gasification followed by low temperature fuel cells (i.e. Proton Exchange Membrane (PEM) fuel cells) (2) Gasification followed by high temperature fuel cells (i.e. Solid Oxide fuel cells (SOFC)) (3) Gasification followed by catalytic combustion (CC) and (4) Incineration with energy recovery. Looking at the result of the four technology chains in terms of the impact categories considered with impact per GWh electricity produced as a unit of comparison and from the perspective of the rank each scenario has in all the four impact categories, SOFC appears to be the winner technology followed by PEM and CC as second and third best respectively with incinerations as the least of all. On other hand, looking at the three important emissions (CO,. NOx and SOx) from the total systems (include both the core system and the external system), SOFC is the best technology equally followed PEM and CC as the second best. A comparison of the same emissions from the core systems places CC on equal level with SOFC as the best technologies with PEM as the second best.
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  • Cai, Zhichang (author)
  • From energy efficiency to integrated sustainable urbanism in residential development in China
  • 2010
  • Licentiate thesis (other academic/artistic)abstract
    • China has adopted Sustainable Development as a national strategy for all industries. In civil construction sector, sustainability is regarded as the development of Green Building in China. Since 2000, China has introduced a series of policies and laws to promote Green Building. Green Building was defined as buildings that are “energy-efficient, land-efficient, water-efficient, and material-efficient” and emit “minimal pollution” in during its entire life cycle, and meets a specified standard for indoor environment at the same time. However, energy efficiency is the central issue of current Green Building development in China, while issues of resources and pollution are neglected, which is partly due to China’s energy structure. Social and economic aspects are also always ignored. The main aim of this thesis is to map pathways towards more comprehensive frameworks for how residential areas in China could be constructed in a more sustainable way in hot –summer and cold-winter area. Case study was the main method used to examine the specifications of Green Residential Building in China. This paper offers a general overview of the current green trend in China and presents a specific analysis on three cases to search for the proper approach for China’s unique situation by three specific cases representing three types of Green Building: Modern Vernacular Architecture, Eco-office and Mass-housing, according to their features in scale, location and function. This paper then presents a specific integrated sustainability analysis of the Landsea Housing Project in Nanjing, a hot-summer/cold-winter zone. Hammarby Sjöstad, a cutting edge project in Stockholm, is also discussed as a reference area from which experiences can be drawn for China. The aim was to improve the framework for construction of residential buildings in China in a more sustainable way, from energy efficiency to integrated sustainability. The paper also discusses the relationship between the economic growth and energy consumption in the fast-growing situation, presents several scenarios depicting energy and comfort and makes suggestions for China. The roles of government, developers and residents are also addressed. The paper argues that an adaptive and holistic approach, which must be expanded from both spatial scale and temporal span, should be established for the Green Residential Building development in China, as an effective way to meet the sustainability goal.
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31.
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32.
  • Ekvall, Tomas, et al. (author)
  • What life-cycle assessment does and does not do in assessments of waste management
  • 2007
  • In: Waste Management. - : Elsevier BV. - 0956-053X .- 1879-2456. ; 27:8, s. 989-996
  • Journal article (peer-reviewed)abstract
    • In assessments of the environmental impacts of waste management, life-cycle assessment (LCA) helps expanding the perspective beyond the waste management system. This is important, since the indirect environmental impacts caused by surrounding systems, such as energy and material production, often override the direct impacts of the waste management system itself. However, the applicability of LCA for waste management planning and policy-making is restricted by certain limitations, some of which are characteristics inherent to LCA methodology as such, and some of which are relevant specifically in the context of waste management. Several of them are relevant also for other types of systems analysis. We have identified and discussed such characteristics with regard to how they may restrict the applicability of LCA in the context of waste management. Efforts to improve LCA with regard to these aspects are also described. We also identify what other tools are available for investigating issues that cannot be adequately dealt with by traditional LCA models, and discuss whether LCA methodology should be expanded rather than complemented by other tools to increase its scope and applicability.
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33.
  • Eriksson, Ola, et al. (author)
  • Municipal Solid Waste Management from a Systems Perspective
  • 2005
  • In: Journal of Cleaner Production. - : Elsevier BV. - 0959-6526 .- 1879-1786. ; 13:3, s. 241-252
  • Journal article (peer-reviewed)abstract
    • Different waste treatment options for municipal solid waste have been studied in a systems analysis. Different combinations of incineration, materials recycling of separated plastic and cardboard containers, and biological treatment (anaerobic digestion and composting) of biodegradable waste, were studied and compared to landfilling. The evaluation covered use of energy resources, environmental impact and financial and environmental costs. In the study, a calculation model ( ) based on methodology from life cycle assessment (LCA) was used. Case studies were performed in three Swedish municipalities: Uppsala, Stockholm, and Älvdalen. The study shows that reduced landfilling in favour of increased recycling of energy and materials lead to lower environmental impact, lower consumption of energy resources, and lower economic costs. Landfilling of energy-rich waste should be avoided as far as possible, partly because of the negative environmental impacts from landfilling, but mainly because of the low recovery of resources when landfilling. Differences between materials recycling, nutrient recycling and incineration are small but in general recycling of plastic is somewhat better than incineration and biological treatment somewhat worse. When planning waste management, it is important to know that the choice of waste treatment method affects processes outside the waste management system, such as generation of district heating, electricity, vehicle fuel, plastic, cardboard, and fertiliser.
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34.
  • Eriksson, Ola, et al. (author)
  • ORWARE : a simulation tool for waste management
  • 2002
  • In: Resources, Conservation and Recycling. - 0921-3449 .- 1879-0658. ; 36:4, s. 287-307
  • Journal article (peer-reviewed)abstract
    • A simulation model, ORWARE (ORganic WAste REsearch) is described. The model is mainly used as a tool for researchers in environmental systems analysis of waste management. It is a computer-based model for calculation of substance flows, environmental impacts, and costs of waste management. The model covers, despite the name, both organic and inorganic fractions in municipal waste. The model consists of a number of separate submodels, which describes a process in a real waste management system. The submodels may be combined to design a complete waste management system. Based on principles from life cycle assessment the model also comprises compensatory processes for conventional production of e.g. electricity, district heating and fertiliser. The compensatory system is included in order to fulfil the functional units, i.e. benefits from the waste management that are kept constant in the evaluation of different scenarios. ORWARE generates data on emissions, which are aggregated into different environmental impact categories, e.g. the greenhouse effect, acidification and eutrophication. Throughout the model all physical flows are described by the same variable vector, consisting of up to 50 substances. The extensive vector facilitates a thorough analysis of the results, but involves some difficulties in acquiring relevant data. Scientists have used ORWARE for 8 years in different case studies for model testing and practical application in the society. The aims have e.g. been to evaluate waste management plans and to optimise energy recovery from waste.
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35.
  • Frostell, Björn M., et al. (author)
  • Modeling both direct and indirect environmental load of purchase decisions : a web-based tool addressing household metabolism
  • 2015
  • In: Environmental Modelling & Software. - : Elsevier BV. - 1364-8152 .- 1873-6726. ; 71, s. 138-147
  • Journal article (peer-reviewed)abstract
    • Consumer awareness is continuously increasing towards pro-environmental behavior. Thus, we developed a web-based environmental feedback tool EcoRunner, which is designed for Swedish households aiming at increasing the awareness in a more pro-environmental direction. The conceptual model of EcoRunner has been developed based on top-down and bottom-up approaches connecting economic activities within a household to environmental pressures (both direct and indirect). In addition, the development of the tool includes a multi-level model aiming at better tailor-made advice to consumers. In this paper, we examine the EcoRunner tool with average single Swedish household expenditures as well as explore options for reductions and systems effects. Analysis shows that food and non-alcoholic beverages, fuel for personal transport (e.g. car) and air transports have significant environmental pressures. In addition, this study suggests that EcoRunner could be used in education systems as an environmental feedback tool to enlighten consumers motivation and change consumption patterns.
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36.
  • Glaumann, Mauritz, 1942-, et al. (author)
  • Basic LCA Application : Residential Building Case study - Gronskar, Sweden
  • 2008
  • In: Sustainability of Constructions. - Cost Action C25 : Addprint AG, Possendorf. - 9783867800945 ; , s. 5:18-5:29
  • Book chapter (other academic/artistic)abstract
    • The aim of this study is to provide a basic introduction to the application of life cycle thinking in building design. This is achieved through the development of a basic MS Excel tool, and applying it to a specific case study. The application of the tool to a new building is intended to illustrate its practical application and its potential as a basis for the choice of energy system and building technology with low environmental impact. The building, Gronskar, referred to in the case study was built by Skanska in Sweden, and is based on the “Moderna hus” concept, with the underlying principle of designing and constructing new efficient residential buildings. The tool is also intended to offer the necessary flexibility in view of the specific circumstances of different countries and available data.  Furthermore the platform chosen allows for potential further development by users.
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37.
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38.
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39.
  • Glaumann, Mauritz, et al. (author)
  • Miljövärdering av bebyggelse : extern miljöpåverkan, beskrivning av olika miljöpåverkanskategorier
  • 2009
  • Reports (other academic/artistic)abstract
    • Den här skriften utgör till största delen en översiktlig beskrivning av de miljöproblem som den moderna människans livsföring bidrar till att skapa i sin omgivning och hur samhället arbetar för att motverka dessa. Syftet är att ge en allmän förståelse för dessa miljöproblem och vad de orsakas av samt peka på vilka förändringar som krävs för att undvika eller eliminera dem. Varje kapitel är disponerat på samma sätt med problembeskrivning, mekanismer, den historiska utvecklingen, problemets omfattning, påverkan på människor samt underlag för EcoEffect-beräkningar. Denna allmänna bild har varit nödvändig att ta fram för att utveckla EcoEffect-metoden, som används för att analysera miljöpåverkan från byggande och användning av byggnader. Miljöproblemen som beskrivs är emellertid inte unika för byggsektorn utan gäller i olika grad också alla andra verksamheter i samhället. Därför bör beskrivningarna i rapporten även kunna vara av intresse för andra som vill tillägna sig en grundläggande förståelse för dagens stora miljöproblem. Rapporten utgör samtidigt en redovisning av det beräkningsunderlag som används för att göra miljöbedömningar i EcoEffect. Dessa uppgifter sammanfattas i slutet av varje kapitel och behöver således inte läsas av personer som inte är intresserade av EcoEffect metoden. Dataredovisningen är disponerad efter beräkningarna i EcoEffect som därför sammanfattas här.
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40.
  • Gu, Zhenhong, et al. (author)
  • A study of Chinese strategies for energy-efficient housing developments from an architect's perspective, combined with Swedish experiences and game theory
  • 2009
  • In: Civil engineering and environmental systems (Print). - : Informa UK Limited. - 1028-6608 .- 1029-0249. ; 26:4, s. 323-338
  • Journal article (peer-reviewed)abstract
    • The energy issue is always an important factor in sustainable housing developments. Over the years, a number of energy-saving techniques have been developed to reduce consumption of primary energy and utilise renewable energy in architectural designs. However, the real situation regarding energy-efficient buildings has improved rather slowly during the recent decades, both in the developing and developed countries. Hammarby Sjostad is one of the largest urban housing developments in Europe but is built to standards twice as strict as those currently being applied for new housing, including energy consumption. Eco-villages are small-scale housing developments, usually in the suburbs, where residents also try to create highly specific ecological environments. There are two basic paradigms to solve the current housing problem: top-down (provider paradigm) or bottom-up (support paradigm). This paper analyses the differences between these, especially from an energy efficiency perspective. Housing development is a gaming process between diverse stakeholders. All the stakeholders try to choose different actions in an attempt to maximise their returns. If the proposals made by the architects and engineers are not consistent with the interests of other stakeholders, they have little chance of being applied in actual projects. This paper describes systematic development strategies for the energy-efficient housing project Jun Lin Zijin, a Chinese residential and commercial project furthering the progress of design and construction.
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41.
  • Gu, Zhenhong, et al. (author)
  • Analysis of the most widely used building environmental assessment methods
  • 2006
  • In: Journal of Environmental Sciences(China). - : Informa UK Limited. - 1001-0742 .- 1878-7320. ; 3:3, s. 175-192
  • Journal article (peer-reviewed)abstract
    • Building Environmental Assessment (BEA) is a term used for several methods for environmental assessment of the building environment. Generally, Life Cycle Assessment (LCA) is an important foundation and part of the BEA method, but current BEA methods form more comprehensive tools than LCA. Indicators and weight assignments are the two most important factors characterizing BEA. From the comparison of the three most widely used BEA methods, EcoHomes (BREEAM for residential buildings), LEED-NC and GBTool, it can be seen that BEA methods are shifting from ecological, indicator-based scientific systems to more integrated systems covering ecological, social and economic categories. Being relatively new methods, current BEA systems are far from perfect and are under continuous development. The further development of BEA methods will focus more on non-ecological indicators and how to promote implementation. Most BEA methods are developed based on regional regulations and LCA methods, but they do not attempt to replace these regulations. On the contrary, they try to extend implementation by incentive programmes. There are several ways to enhance BEA in the future: expand the studied scope from design levels to whole life-cycle levels of constructions, enhance international cooperation, accelerate legislation and standardize and develop user-oriented assessment systems.
  •  
42.
  • Idh, Jonna, et al. (author)
  • Kinetics of the QuantiFERON((R))-TB Gold In-Tube test during treatment of patients with sputum smear-positive tuberculosis in relation to initial TST result and severity of disease
  • 2010
  • In: Scandinavian journal of infectious diseases. - : Informa UK Limited. - 1651-1980 .- 0036-5548. ; 42:9, s. 650-657
  • Journal article (peer-reviewed)abstract
    • Abstract The QuantiFERON((R))-TB Gold In-Tube test (QFN) measures interferon-gamma production in response to Mycobacterium tuberculosis antigens. Our aim was to assess the kinetics of the QFN and initial tuberculin skin test (TST) result in relation to severity of disease in a tuberculosis (TB) endemic area. Smear-positive TB patients (n = 71) were recruited at Gondar University Hospital, Ethiopia. The TST, QFN, CD4+ cell count and clinical symptoms (TB score) were assessed and followed up during treatment. From baseline to 7 months after treatment, there was a significant decrease in QFN reactivity (93.8% to 62.5% in HIV-negative/TB; 70.3% to 33.3% in HIV-positive/TB patients) down to a level comparable to a control group of blood donors (51.2%). The agreement between TST and QFN was poor in TB patients compared to healthy controls. A negative TST correlated to more advanced TB in contrast to a negative QFN test. We conclude that the QFN reactivity is significantly reduced at the end of treatment against active TB to the background level of healthy blood donors, and that the agreement between TST and QFN is poor including correlation to the severity of disease.
  •  
43.
  • Idh, Jonna, et al. (author)
  • Nitric oxide production in the exhaled air of patients with pulmonary tuberculosis in relation to HIV co-infection
  • 2008
  • In: BMC Infectious Diseases. - : Springer Science and Business Media LLC. - 1471-2334. ; 8:146
  • Journal article (peer-reviewed)abstract
    • Background: Nitric oxide (NO) is essential for host defense in rodents, but the role of NO during tuberculosis (TB) in man remains controversial. However, earlier observations that arginine supplementation facilitates anti-TB treatment, supports the hypothesis that NO is important in the host defense against TB. Local production of NO measured in fractional exhaled air (FeNO) in TB patients with and without HIV co-infection has not been reported previously. Thus, our aim was to investigate levels of FeNO in relation to clinical symptoms and urinary NO metabolites (uNO). Methods: In a cross sectional study, FeNO and uNO were measured and clinical symptoms, chest x-ray, together with serum levels of arginine, tumor necrosis factor alpha (TNF-alpha) and interleukin 12 (IL-12) were evaluated in sputum smear positive TB patients (HIV+/TB, n = 36, HIV-/TB, n = 59), their household contacts (n = 17) and blood donors (n = 46) from Gondar University Hospital, Ethiopia. Results: The proportion of HIV-/TB patients with an increased FeNO level (> 25 ppb) was significantly higher as compared to HIV+/TB patients, but HIV+/TB patients had significantly higher uNO than HIV-/TB patients. HIV+ and HIV-/TB patients both had lower levels of FeNO compared to blood donors and household contacts. The highest levels of both uNO and FeNO were found in household contacts. Less advanced findings on chest x-ray, as well as higher sedimentation rate were observed in HIV+/TB patients as compared to HIV-/TB patients. However, no significant correlation was found between FeNO and uNO, chest x-ray grading, clinical symptoms, TNF-alpha, IL-12, arginine levels or sedimentation rate. Conclusion: In both HIV negative and HIV co infected TB patients, low levels of exhaled NO compared to blood donors and household were observed. Future studies are needed to confirm whether low levels of exhaled NO could be a risk factor in acquiring TB and the relative importance of NO in human TB.
  •  
44.
  • Norrman Eriksson, Ola, et al. (author)
  • Life cycle impact assessment - damage based weighting method for environmental impact assessment
  • 2005
  • In: Action for Sustainability: Proceedings of the 2005 World Sustainable Building Conference in Tokyo.
  • Conference paper (peer-reviewed)abstract
    • This paper describes the conceptual framework for a damage value-oriented weighting method for endpoint problems. It is developed with the aim to be transparent, and with a minimum of subjective features. Calculations of external environmental impacts are based on data for material- and energy flows, emission factors, and characterisation of emissions into contribution to environmental impact categories. These environmental impact values are then weighted by using damage values (total number of DALY (Disability Adjusted Life Years)) for each type of problem. Estimations of the number of persons possibly affected by a problem caused by emissions have been made and multiplied by the severity for each affected person. The category weight is the sum of all damage values in an impact category. This approach has several advantages: (1) A clear distinction between the characterization step and valuation step of the LCA, (2) A knowledge driven method where an improvement in quality and reliability of information and data used can be easily introduced to the framework. The method also suffers from some disadvantages: (1) As in other weighting methods, forecasts about the future in terms of scenarios do always mean an uncertainty and (2) Local and regional environmental problems are extrapolated to global effects, which means that uncertainties are introduced.
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45.
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46.
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47.
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48.
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49.
  • Stanaway, Jeffrey D., et al. (author)
  • Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017
  • 2018
  • In: The Lancet. - 1474-547X .- 0140-6736. ; 392:10159, s. 1923-1994
  • Journal article (peer-reviewed)abstract
    • Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk-outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk-outcome pairs, and new data on risk exposure levels and risk- outcome associations. Methods We used the CRA framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017. This study included 476 risk-outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. We explored the relationship between development and risk exposure by modelling the relationship between the Socio-demographic Index (SDI) and risk-weighted exposure prevalence and estimated expected levels of exposure and risk-attributable burden by SDI. Finally, we explored temporal changes in risk-attributable DALYs by decomposing those changes into six main component drivers of change as follows: (1) population growth; (2) changes in population age structures; (3) changes in exposure to environmental and occupational risks; (4) changes in exposure to behavioural risks; (5) changes in exposure to metabolic risks; and (6) changes due to all other factors, approximated as the risk-deleted death and DALY rates, where the risk-deleted rate is the rate that would be observed had we reduced the exposure levels to the TMREL for all risk factors included in GBD 2017.
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