↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Ayora S) "

Search: WFRF:(Ayora S)

Result 1-2 of 2

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Malago, M, et al. (author) Outcomes of elective liver surgery worldwide: a global, prospective, multicenter, cross-sectional study 2023 In: International journal of surgery (London, England). - 1743-9159. ; 109:12, s. 3954-3966 Journal article (peer-reviewed)
2.	Corvaisier, Matthieu, et al. (author) The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cells 2021 In: Communications biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 4:1, s. 767- Journal article (peer-reviewed)abstract Changes in the location of γ-tubulin ensure cell survival and preserve genome integrity. We investigated whether the nuclear accumulation of γ-tubulin facilitates the transport of proliferating cell nuclear antigen (PCNA) between the cytosolic and the nuclear compartment in mammalian cells. We found that the γ-tubulin meshwork assists in the recruitment of PCNA to chromatin. Also, decreased levels of γ-tubulin reduce the nuclear pool of PCNA. In addition, the γ-tubulin C terminus encodes a PCNA-interacting peptide (PIP) motif, and a γ-tubulin–PIP-mutant affects the nuclear accumulation of PCNA. In a cell-free system, PCNA and γ-tubulin formed a complex. In tumors, there is a significant positive correlation between TUBG1 and PCNA expression. Thus, we report a novel mechanism that constitutes the basis for tumor growth by which the γ-tubulin meshwork maintains indefinite proliferation by acting as an opportune scaffold for the transport of PCNA from the cytosol to the chromatin.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-2 of 2

Refine your search

Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Erdmann, J. (1); Gomes, A. (1); Zhang, F. (1); Zhang, R. (1); Liu, C. (1); Ahmed, H. (1); show more...; Li, J. (1); Petric, M. (1); Verhoef, C (1); Kumar, A. (1); Marino, C. (1); Masetti, M. (1); Sandstrom, P. (1); Zhang, B. (1); Castro, E (1); Negoi, I (1); Abbassi, F (1); Hernandez-Alejandro, ... (1); Sapisochin, G (1); Zieniewicz, K (1); Armstrong, T. (1); Ferrero, A. (1); Di Martino, M. (1); Monaco, A. (1); Lee, B. (1); Sherif, A. (1); Hidalgo, C (1); Line, PD (1); Grat, M (1); Lodge, P (1); Reese, T (1); Romano, F (1); Abu Hilal, M (1); Vivarelli, M (1); Hoti, E (1); Lang, H (1); Strupas, K (1); Varghese, C (1); Robertson, F (1); Elhadi, M (1); Schnitzbauer, AA (1); Tsoulfas, G (1); Fuks, D (1); Konstadoulakis, M (1); Arkadopoulos, N (1); Kokoropoulos, P (1); Sidiropoulos, T (1); Diamantis, A (1); Perivoliotis, K (1); Schizas, D (1); show less...

University: Karolinska Institutet (2); Lund University (1)

Language: English (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view