↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Badji R) "

Search: WFRF:(Badji R)

Result 1-8 of 8

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Niemi, MEK, et al. (author) 2021 swepub:Mat__t
2.	Kanai, M, et al. (author) 2023 swepub:Mat__t
3.	Shrine, N, et al. (author) Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk 2023 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 55:3, s. 410- Journal article (peer-reviewed)abstract Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 participants, we identified 1,020 independent association signals implicating 559 genes supported by ≥2 criteria from a systematic variant-to-gene mapping framework. These genes were enriched in 29 pathways. Individual variants showed heterogeneity across ancestries, age and smoking groups, and collectively as a genetic risk score showed strong association with COPD across ancestry groups. We undertook phenome-wide association studies for selected associated variants as well as trait and pathway-specific genetic risk scores to infer possible consequences of intervening in pathways underlying lung function. We highlight new putative causal variants, genes, proteins and pathways, including those targeted by existing drugs. These findings bring us closer to understanding the mechanisms underlying lung function and COPD, and should inform functional genomics experiments and potentially future COPD therapies.
4.	Kerbrat, A, et al. (author) Multiple sclerosis lesions in motor tracts from the brain to the cervical cord: spatial distribution and correlation with functional deficits 2019 In: MULTIPLE SCLEROSIS JOURNAL. - 1352-4585. ; 25, s. 922-923 Conference paper (other academic/artistic)
5.	Eden, D, et al. (author) Spatial distribution of multiple sclerosis lesions in the cervical spinal cord 2019 In: Brain : a journal of neurology. - : Oxford University Press (OUP). - 1460-2156. ; 142:3, s. 633-646 Journal article (peer-reviewed)
6.	Gros, C, et al. (author) Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks 2019 In: NeuroImage. - : Elsevier BV. - 1095-9572 .- 1053-8119. ; 184, s. 901-915 Journal article (peer-reviewed)
7.	Ferreira, Pamela C. L., et al. (author) Endocannabinoid System Biomarkers in Alzheimer's Disease 2023 In: CANNABIS AND CANNABINOID RESEARCH. - : Mary Ann Liebert Inc. - 2578-5125 .- 2378-8763. ; 8:1, s. 77-91 Journal article (peer-reviewed)abstract Background: Alterations in the endocannabinoid system (ES) have been described in Alzheimer's disease (AD) pathophysiology. In the past years, multiple ES biomarkers have been developed, promising to advance our understanding of ES changes in AD.Discussion: ES biomarkers, including positron emission tomography with cannabinoid receptors tracers and biofluid-based endocannabinoids, are associated with AD disease progression and pathological features.Conclusion: Although not specific enough for AD diagnosis, ES biomarkers hold promise for prognosis, drug-target engagement, and a better understanding of the disease. Here, we summarize currently available ES biomarker findings and discuss their potential applications in the AD research field.
8.	Mangeat, G, et al. (author) Changes in structural network are associated with cortical demyelination in early multiple sclerosis 2018 In: Human brain mapping. - : Wiley. - 1097-0193 .- 1065-9471. ; 39:5, s. 2133-2146 Journal article (peer-reviewed)

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-8 of 8

Refine your search

Type of publication: journal article (5); conference paper (1)

Type of content: peer-reviewed (5); other academic/artistic (1)

Author/Editor: Mbarek, H (3); Brown, J. (2); Clark, A. (2); Cole, S. (2); Davies, M. (2); Endo, M. (2); show more...; Erdmann, J. (2); Fox, H. (2); Hasegawa, Y. (2); Hughes, G. (2); Jackson, M. (2); Jackson, P. (2); Karthik, K. (2); Lee, H. (2); Lewis, A. (2); Maeno, T. (2); Saleem, M. (2); Suzuki, Y. (2); Walker, R. (2); White, S. (2); Williams, S. (2); Wilson, A. (2); Wright, M. (2); Wu, Y. (2); Yamada, M. (2); Nagata, K. (2); Davidson, N. (2); Dobson, E. (2); Harvey, A. (2); Lange, C. (2); Oliveira, M. (2); Rose, A. (2); Grau, N. (2); Haider, S. (2); Tokunaga, K. (2); Davies, E (2); Suzuki, S (2); Gupta, A. (2); Robinson, M. (2); Dennis, C. (2); Marshall, R. (2); Smith, M. (2); Martin, J. (2); Davies, G (2); Harris, C (2); Kumar, S (2); Brown, A. (2); Brown, E. (2); Clark, M. (2); Hays, C. (2); show less...

University: Karolinska Institutet (7); University of Gothenburg (1); Uppsala University (1); Lund University (1)

Language: English (8)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view